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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Clear lenses Clear all
Completed Not applicable Interventional Results available

The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses

NCT05766787
View directory record Official record
Conditions
Refractive Ametropia
Interventions
Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
15
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Light Sleep: Screen Use and Sleep Health

NCT05342662
View directory record Official record
Conditions
Glasses
Interventions
Blue light-blocking glasses, Glasses with clear lenses
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 29 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients

NCT00799422
View directory record Official record
Conditions
Conjunctival Staining
Interventions
Complete Easy Rub, ReNu MultiPlus, Clear Care, Contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2012 · Synced Sep 29, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Blue Light Intraocular Lenses (IOLs) and Photostress

NCT00710996
View directory record Official record
Conditions
Cataract
Interventions
Not listed
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2010 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

NCT01250925
View directory record Official record
Conditions
Myopia, Refractive Error
Interventions
ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Iowa City, Iowa • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of A New Contact Lens Cleaning and Disinfecting Solution

NCT01318577
View directory record Official record
Conditions
Vision Disorders
Interventions
Investigational Cleaning & Disinfecting Solution, Clear Care Solution
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses

NCT05959200
View directory record Official record
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens

NCT05765227
View directory record Official record
Conditions
Refractive Ametropia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses

NCT06165627
View directory record Official record
Conditions
Ametropia, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 45 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
5
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens

NCT05211739
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of a HYDRAGLYDE® Regimen

NCT03026257
View directory record Official record
Conditions
Refractive Errors, Myopia, Hypermetropia
Interventions
Lotrafilcon B contact lenses with added wetting agent, Samfilcon A contact lenses, POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent, Hydrogen peroxide-based contact lens solution with added wetting agent, Senofilcon C contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Habitual Multi-Purpose Solution (HMPS)
Device
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
5
States / cities
Birmingham, Alabama • Cleveland, Ohio • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

NCT05338333
View directory record Official record
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
8
States / cities
Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification

NCT01454063
View directory record Official record
Conditions
Intraocular Lens Replacement
Interventions
OMS302, Placebo
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
18 Years and older
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
16
States / cities
Chandler, Arizona • Glendale, Arizona • Los Angeles, California + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Sep 29, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity

NCT07223086
View directory record Official record
Conditions
Concussion, Mild, Photophobia, Contact Lens
Interventions
Narrow band (tinted) contact lenses, broad band (clear) contact lenses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of 3 Contact Lens Materials With 3 Solution Types

NCT03466060
View directory record Official record
Conditions
Visual Acuity, Slit Lamp Biomicroscopy (Corneal Staining Assessment)
Interventions
Opti-Free : RevitaLens / Clear Care : RevitaLens, Opti-Free : RevitaLens / RevitaLens : Clear Care, Clear Care : RevitaLens/ Opti-Free : RevitaLens, Clear Care : RevitaLens / RevitaLens : Opti-Free, RevitaLens : Clear Care/ Opti-Free : RevitaLens, RevitaLens : Clear Care / RevitaLens : Opti-Free, RevitaLens : Opti-Free / Clear Care : RevitaLens, RevitaLens : Opit-Free / RevitaLens : Clear Care
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
5
States / cities
Anaheim, California • Berkeley, California • Jacksonville, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Daily Wear Corneal Infiltrative Event Study

NCT00937105
View directory record Official record
Conditions
Myopia, Hyperopia, Corneal Infiltrative Events
Interventions
lotrafilcon A contact lenses, Renu Multiplus, Clear Care
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
15 Years and older
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2014 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Clinical Outcomes Following Implantation of Tecnis Synergy and Symfony Intraocular Lens

NCT05541796
View directory record Official record
Conditions
Cataract
Interventions
Intraocular lens
Device
Lead sponsor
George O. Waring IV
Other
Eligibility
40 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

NCT06469242
View directory record Official record
Conditions
Presbyopia
Interventions
Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
8
States / cities
Los Angeles, California • Oakland, California • Maitland, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure

NCT00804999
View directory record Official record
Conditions
Normal Contact Lens Wear
Interventions
Clear Care, ReNu, OPTI-FREE
Drug
Lead sponsor
Christine Sindt
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blue Blockers at Night and Insomnia Symptoms

NCT02698800
View directory record Official record
Conditions
Insomnia, Sleep
Interventions
Blue blocking (BB) lenses, Clear lenses
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Phase 3 Interventional Results available

Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification

NCT01579565
View directory record Official record
Conditions
Intraocular Lens Replacement
Interventions
OMS302, Placebo
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
13
States / cities
Chandler, Arizona • Los Angeles, California • Fort Myers, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Performance of Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution in a New Packaging Configuration

NCT00659815
View directory record Official record
Conditions
Comfort
Interventions
Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in the Currently Marketed Resin Bottle., Bausch & Lomb ReNu MultiPlus Multi-Purpose Solution Packaged in a Clear Resin Bottle.
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2011 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of Two Reusable Silicone Hydrogel Contact Lenses

NCT05050578
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
10
States / cities
Oakland, California • San Francisco, California • Longwood, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2023 · Synced Sep 29, 2026, 5:15 AM EDT
Completed Not applicable Interventional Results available

Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses

NCT05702541
View directory record Official record
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 29, 2026, 5:15 AM EDT