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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Study of Home-Embedded Palliative Care for Hemodialysis-Dependent End-Stage Renal Disease

NCT05471622
View directory record Official record
Conditions
End-Stage Renal Disease
Interventions
Nudge for PHPC Referral
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Improving Inpatient Screening for Hepatitis C

NCT04525690
View directory record Official record
Conditions
Hepatitis C
Interventions
Nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
7,634 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Sep 4, 2026, 6:22 PM EDT
Enrolling by invitation Not applicable Interventional

Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters

NCT07636187
View directory record Official record
Conditions
Behavior, Health
Interventions
Pre-visit and post-visit patient messaging, Default pended order, EHR communication
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
16,416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Advanced Heart Care at Home

NCT03724695
View directory record Official record
Conditions
Palliative Care, Heart Failure, Health Care Utilization, Quality Improvement
Interventions
Clinician nudge or opt out approach for AHCAH liaison visit
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
709 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Effect of Behavioral Nudges on Serious Illness Conversation Documentation

NCT04867850
View directory record Official record
Conditions
Cancer
Interventions
Usual Care, Clinician Nudge, Patient Nudge
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
4,450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional

A Pragmatic Trial of an Active Choice Nudge for Generalist or Specialist Palliative Care for Seriously Ill Inpatients

NCT05502861
View directory record Official record
Conditions
Palliative Care
Interventions
Generalist + Specialist palliative care, Pre-Intervention phase
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
18,884 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Active, not recruiting Not applicable Interventional

Nudge to Gynecologic Oncology

NCT06451263
View directory record Official record
Conditions
Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
Interventions
Nudge
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Recruiting Not applicable Interventional

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT06377033
View directory record Official record
Conditions
Genetic Predisposition, Paraganglioma, Pheochromocytoma, ALS, Parkinson Disease, Polyneuropathies, Frontotemporal Dementia, Alzheimer Disease, Cardiomyopathy Non-ischemic, Thoracic Aortic Aneurysm
Interventions
Behavioral nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Increasing Screening for Cancer Using EHR-Nudges

NCT06177795
View directory record Official record
Conditions
Breast Cancer
Interventions
Post-visit patient text messaging, Default pended order, High risk bidirectional post-visit text messaging
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
40 Years to 74 Years · Female only
Enrollment
21,123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Cleveland, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Recruiting Not applicable Interventional

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention

NCT06436157
View directory record Official record
Conditions
Solid Tumor, Adult
Interventions
Enhanced education, Usual care education
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Chico, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Behavioral Economics to Improve Flu Vaccination Using EHR Nudges

NCT06057727
View directory record Official record
Conditions
Behavior, Health, Flu, Flu Vaccination
Interventions
Pre-visit patient text messaging, Default pended order, Monthly peer comparison feedback, High risk bidirectional pre-visit text messaging
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
80,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Current Opioid-User Population

NCT04601480
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Abuse
Interventions
Choice Architecture Nudge, PMP Integration & Nudge
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Increasing Adherence to Lung Cancer Screening

NCT05832008
View directory record Official record
Conditions
Lung Cancer, Adherence, Patient
Interventions
Patient Nudge, Clinician Nudge
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 80 Years
Enrollment
825 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Active, not recruiting Not applicable Interventional

Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC)

NCT05629065
View directory record Official record
Conditions
Breast Cancer, Gastrointestinal Cancer, Gynecologic Cancer, Thoracic Cancer, Genitourinary Cancer
Interventions
Clinician Nudge Email, Patient Nudge Letter and Share questionaire
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Improving Tobacco Treatment Rates for Outpatient Cancer Patients Who Smoke

NCT04737031
View directory record Official record
Conditions
Cancer, Smoking, Tobacco Use, Nicotine Dependence
Interventions
Clinician Nudge, Patient Nudge
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
Not listed
Enrollment
2,146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Lancaster, Pennsylvania • Philadelphia, Pennsylvania • West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Machine-Generated Mortality Estimates and Nudges to Promote Advance Care Planning Discussion Among Cancer Patients

NCT03984773
View directory record Official record
Conditions
Oncology
Interventions
Nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 4, 2026, 6:22 PM EDT
Terminated Not applicable Interventional

Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease

NCT06144281
View directory record Official record
Conditions
End-Stage Renal Disease
Interventions
Nudge for PHPC NP Referral
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
315 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Active, not recruiting Not applicable Interventional

Testing a Brief Reassurance Message Before a Musculoskeletal Clinic Visit

NCT07330492
View directory record Official record
Conditions
Any Non-traumatic Musculoskeletal Condition
Interventions
Nudge intervention
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges

NCT04477304
View directory record Official record
Conditions
Opioid Abuse, Unspecified
Interventions
Opioid Naive, OR, At-risk for long-term use, OR, Long-term opioid recipient
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
555 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Enrolling by invitation Not applicable Interventional

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

NCT05852860
View directory record Official record
Conditions
HIV, Smoking, Tobacco Use, Nicotine Dependence
Interventions
Clinician Nudge, Patient Nudge
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Withdrawn Not applicable Interventional

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase

NCT03791580
View directory record Official record
Conditions
Fall, Congestive Heart Failure, Chronic Kidney Failure, Adverse Drug Event
Interventions
Commitment nudge, Justification nudge
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Active, not recruiting Not applicable Interventional

Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening

NCT05693649
View directory record Official record
Conditions
Colorectal Cancer
Interventions
No Direct Patient Outreach, Direct Patient Outreach: Colonoscopy Only, Direct Patient Outreach: Sequential Choice, Visit-Based Nudge/Text, No Nudge/Text
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
50 Years to 72 Years
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

Behavioral Economics to Improve Flu Vaccination Using EHR Nudges Replication

NCT06626321
View directory record Official record
Conditions
Behavior, Health, Flu, Flu Vaccination
Interventions
Pre-visit patient text messaging, Default pended order, Monthly peer comparison feedback, High risk bidirectional pre-visit text messaging
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
26,248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 4, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers

NCT04601506
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Abuse
Interventions
Choice Architecture Nudge, PMP Integration & Nudge
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 4, 2026, 6:22 PM EDT