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ClinicalTrials.gov public records Last synced Oct 17, 2026, 7:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–39 of 39 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Clonidine Injection Clear all

Conditions: Opioid-use Disorder, Mental Health Disorder
Interventions: Collaborative Care for Mental Health Symptoms, Collaborative Care for Opioid Use Disorder and Mental Health Symptoms; Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 254 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 33
States / cities: Washington D.C., District of Columbia • Atlanta, Georgia • Dunwoody, Georgia + 22 more

Conditions: Osteoarthritis, Post-traumatic; Arthrosis
Interventions: methylprednisolone acetate, active comparator; Drug
Lead sponsor: New Lexington Clinic; Other
Eligibility: 18 Years to 95 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions: Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo; Drug · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Osteoarthritis, Hip
Interventions: Periarticular injection (Deep injection), Periarticular injection (Superficial injection), Bupivacaine, Placebo; Procedure · Drug
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 50 Years to 75 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Lumbosacral Radiculopathy
Interventions: Clonidine Micropellets, Sham; Combination Product · Other
Lead sponsor: Sollis Therapeutics, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 207 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 33
States / cities: Mobile, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 28 more

Conditions: Ankle Fractures
Interventions: Long-Acting Local Anesthesia, Regional Anesthesia; Drug
Lead sponsor: Lahey Clinic; Other
Eligibility: 18 Years to 89 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Burlington, Massachusetts

Conditions: Postoperative Pain
Interventions: lidocaine (1%) + bupivacaine (0.5%), Normal saline, Lidocaine (1%) + Bupivacaine (0.5%) + Clonidine (25mcg); Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 3 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Musculoskeletal Diseases, Soft Tissue Mass
Interventions: Exparel Injectable Product, Multi-Drug Cocktail (Ropivicaine, Epinephrine, Ketolorac, Clonidine); Drug
Lead sponsor: Atlantic Health System; Other
Eligibility: 18 Years and older
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Morristown, New Jersey

Conditions: Malignant Neoplasms of Male Genital Organs
Interventions: Caudal Nerve Block (CNB), Ropivacaine, Epinephrine, Decadron, Clonidine, Propofol, Phone Call; Procedure · Drug · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Femoracetabular Impingement, Pain, Postoperative
Interventions: Morphine with clonidine, Normal saline; Drug · Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Interventions: Clonidine, Triamcinolone hexacetonide, Lidocaine HCl; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Hip Dysplasia, Femoroacetabular Impingement, Acetabular Labrum Tear
Interventions: ropivicaine, clonidine, Epinephrine, Noropin; Drug
Lead sponsor: The Hawkins Foundation; Other
Eligibility: 18 Years to 65 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Pain Management
Interventions: ACB Control - 20 ml saline injection for ACB, ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block, Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline; Other · Drug
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Orange, California

Conditions: Pain
Interventions: clonidine; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 2
States / cities: Winston-Salem, North Carolina

Conditions: Breast Cancer
Interventions: Liposomal bupivacaine, Bupivacaine, epinephrine, dexamethasone, and clonidine; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

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Collaborating to Heal Addiction and Mental Health in Primary Care

Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?

Effect of RECK in Posterior Spinal Fusion

Minimal Opioid Use After Total Hip Replacement (THR)

Treatment of Pain Associated With Lumbosacral Radiculopathy in Adults

Randomized Controlled Trial for Ankle Fracture Pain Control

Pediatric Tonsillectomy Pain Reduction Study

"The Efficacy of Exparel Versus a Multidrug Cocktail in Soft Tissue Tumors"

Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis

Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy

Epidural Clonidine for Lumbosacral Radiculopathy

Hip Scope Fascia-iliaca (FI) Block Study

Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?

Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic Pain

RCT Comparing ESPB Solutions in Breast Surgery