Search | Clinical Trials Finder

Independent directory Public ClinicalTrials.gov records United States

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 352 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Closed-loop Clear all

Conditions: Type 1 Diabetes Mellitus
Interventions: Fiasp®, Novolog®, 670G hybrid closed loop continuous subcutaneous insulin infusion system; Drug · Device
Lead sponsor: Texas Diabetes & Endocrinology, P.A.; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Type 1 Diabetes Mellitus
Interventions: Closed-loop Insulin Pump therapy, Standard Insulin Pump Therapy; Device
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 6 Months to 7 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Diabetes Mellitus, Type 1
Interventions: CGM and Insulin Pump, Closed-Loop Control System; Device
Lead sponsor: Sansum Diabetes Research Institute; Other
Eligibility: 21 Years to 65 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 3
States / cities: Santa Barbara, California • Rochester, Minnesota • Charlottesville, Virginia

Conditions: Type 1 Diabetes
Interventions: Automated Insulin Delivery Adaptive NETwork (AIDANET), AIDANET+ BPS_RL→AIDANET; Device
Lead sponsor: Sue Brown; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Diabetes Mellitus, Type 1
Interventions: Placebo and Insulin monotherapy via CL, Sitagliptin and insulin/novolog via CL; Drug
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 14 Years to 30 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Type 1 Diabetes Mellitus, Autoimmune Diabetes, Juvenile-Onset Diabetes, Diabetes, Mellitus, Type 1
Interventions: Hybrid Closed-loop System, Sensor-augmented pump; Device
Lead sponsor: Bruce A. Buckingham; Other
Eligibility: 10 Years to 35 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: Stanford, California

Conditions: Hypertension, Rheumatoid Arthritis
Interventions: Blood pressure intervention arm; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Spinal Cord Injuries
Interventions: hand movements (signals from thumb muscle) triggered PNS and TMS; Device
Lead sponsor: Bronx VA Medical Center; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Post-bariatric Hypoglycemia
Interventions: glucagon, Closed loop glucagon pump; Drug · Device
Lead sponsor: Joslin Diabetes Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Parkinson Disease
Interventions: STN alone, GPi alone, STN + GPi, Closed-loop stimulation; Device
Lead sponsor: Dennis Turner, M.D.; Other
Eligibility: 18 Years to 75 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Type 1 Diabetes Mellitus, Pregnancy in Diabetes
Interventions: Hybrid closed-loop therapy, Sensor-augmented pump therapy; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: Aurora, Colorado • Columbus, Ohio

Conditions: Diabetes Mellitus, Type 1
Interventions: Diabetes Navigator; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 5 Years to 75 Years
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Glucose, Low Blood, Glucose, High Blood
Interventions: Dose Safety AP system; Device
Lead sponsor: Dose Safety Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Redmond, Washington

Conditions: Parkinson Disease
Interventions: Open Loop DBS, Adaptive (Closed Loop) DBS, Intermittent Open Loop DBS; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Stanford, California

Conditions: MCI, Subjective Cognitive Decline (SCD), Mild Behavioral Impairment
Interventions: Cognitive Remediation, Cognitive Remediation II; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 60 Years to 89 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Anesthesia, General
Interventions: ReinLoop control software for patient-specific induction and maintenance of anesthesia, Propofol; Device · Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Stanford, California

Conditions: Type 1 Diabetes Mellitus
Interventions: AID System, Insulin Lispro; Device · Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Walnut Creek, California

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Telehealth Integrated Primary Care (TIPC); Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Type 1 Diabetes
Interventions: Medtronic MiniMed Closed Loop (CL) System, Snacking; Device · Other
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 44 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Type 1 Diabetes Mellitus
Interventions: Closed-Loop Control, Sensor Augmented Pump Therapy; Device · Other
Lead sponsor: Daniel Chernavvsky, MD, CRC; Other
Eligibility: 10 Years to 25 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 2
States / cities: Aurora, Colorado • Charlottesville, Virginia

Conditions: Diabetes Mellitus, Type 1
Interventions: Closed-loop session; Device
Lead sponsor: Sansum Diabetes Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Santa Barbara, California

Conditions: Type 1 Diabetes
Interventions: Glucagon-only Bionic Pancreas; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 21 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Type 1 Diabetes
Interventions: Multiplex pharmacokinetic profiling, Continuous insulin monitoring; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Epilepsy in Children, Epilepsy
Interventions: Attention Intervention using a customized BCI decoder, Attention Intervention without using a customized BCI decoder; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 8 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Austin, Texas