Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 144 matching trials from the live ClinicalTrials.gov search.
Not listed Not applicable Interventional Accepts healthy volunteers

Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure

NCT04359082
Conditions
Cold Exposure, Manual Dexterity, Gut Microbiome
Interventions
CocoaVia supplement, Placebo Pill
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 49 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Natick, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

An Evaluation of the Effects of a Non-Caffeinated Energy Dietary Supplement

NCT04895800
Conditions
Health Behavior
Interventions
Phytovive, Placebo, Caffeine
Dietary Supplement
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Davie, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Modulation of Neuroinflammation in Age-Related Memory Disorders

NCT03723694
Conditions
Memory Loss, Inflammation
Interventions
650 mg of Cocoapro flavanols, 0 mg of Cocoapro flavanols
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
50 Years to 69 Years
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Phase 2 Interventional Results available

CHOCOlate MeLatonin for AdolescenT MigrainE

NCT03597529
Conditions
Migraine
Interventions
Melatonin
Drug
Lead sponsor
Amy Gelfand
Other
Eligibility
3 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Flavanols In Cardiovascular Function in Healthy Aging

NCT01395277
Conditions
Aging
Interventions
High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Austin, Texas
Completed Phase 1 Interventional Accepts healthy volunteers

Cocoa and Endothelial Function in Adults With Elevated BMI

NCT00538083
Conditions
Cardioprotection
Interventions
Chocolate
Other
Lead sponsor
Griffin Hospital
Other
Eligibility
30 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Derby, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Validating the "Foods for Health" Portfolio of Functional Food Products

NCT02341924
Conditions
Hypercholesterolemia
Interventions
Portfolio of functional foods, Control foods
Other
Lead sponsor
University of Manitoba
Other
Eligibility
21 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Healthy
Interventions
CF Control, CF-Theobromine, CF-Caffeine
Other
Lead sponsor
University of California, Davis
Other
Eligibility
25 Years to 60 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
2
States / cities
Davis, California
Conditions
Anesthesia, Pediatrics
Interventions
Inhalation induction with parosmia
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years to 13 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nighttime Feeding and Morning Endurance Performance

NCT02160873
Conditions
Poor Performance Status
Interventions
chocolate milk, flavor-matched placebo
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Tallahassee, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Nutrient Timing Following Resistance Exercise

NCT01674049
Conditions
Type 2 Diabetes
Interventions
Immediate Nutrition, Nutrition 3 hours Post-Bout, Resistance Exercise
Dietary Supplement · Other
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Accepts healthy volunteers

Investigating the Effects of Cocoa Flavanol on Cognition Assessed Online

NCT04582617
Conditions
Aging, Cognitive Change
Interventions
Cocoa Extract, Cocoa Extract Placebo, Multivitamin, Multivitamin placebo
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
65 Years and older
Enrollment
3,959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Conditions
Type 2 Diabetes
Interventions
Cocoa polyphenols
Dietary Supplement
Lead sponsor
Arpita Basu
Other
Eligibility
21 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stillwater, Oklahoma
Completed Not applicable Interventional Accepts healthy volunteers

Buck Institute Ketone Ester RCT

NCT05585762
Conditions
Tolerance, Safety Issues, Aging
Interventions
Ketone ester, Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Novato, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance

NCT05232669
Conditions
Fall, Physical Performance, Fracture
Interventions
Cocoa extract, Cocoa extract placebo, Multivitamin, Multivitamin placebo
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
60 Years and older
Enrollment
21,442 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Depression, Major Depressive Disorder
Interventions
CocoaVia, Placebo
Dietary Supplement · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effect of Vitamin D Statues on Endothelial Function

NCT01049048
Conditions
Cardiovascular Diseases, Vitamin D Deficiency
Interventions
Vitamin D3, Placebo
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Food Consumption, Perseverance
Interventions
Simple physical task, Complex physical task, Cookies, Vegetables, No physical task
Behavioral · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers Results available

Whey Protein Supplementation in High School Athletes

NCT05589129
Conditions
Body Weight Changes, Athletic Performance, Recovery, Sleep
Interventions
Whey Protein Supplement, Carbohydrate Placebo Control
Dietary Supplement
Lead sponsor
University of Utah
Other
Eligibility
13 Years to 18 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Cancer-related Fatigue
Interventions
Guarana herb, Usual Care
Dietary Supplement · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Rochester, New York
Conditions
Breastfeeding
Interventions
Pomegranate Juice
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Stearic Acid and Endothelial Function

NCT07831603
Conditions
Healthy Middle-aged Subjects, Obesity & Overweight
Interventions
High Palmitic Acid Diet, Stearic Acid Test Meal, Oleic Acid Test Meal, High Stearic Acid Diet, High Oleic Acid Diet, Palmitic Acid Test Meal
Other
Lead sponsor
Florida State University
Other
Eligibility
40 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a B12 Vitamin to Increase Energy and Focus

NCT05517005
Conditions
B12 Deficiency Vitamin, Energy Supply; Deficiency, Mood
Interventions
Hype Bites Supplement
Dietary Supplement
Lead sponsor
Sourse
Industry
Eligibility
24 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Completed No phase listed Observational

Chocolate Balloon Angioplasty Registry

NCT01589042
Conditions
Peripheral Arterial Disease
Interventions
Not listed
Lead sponsor
TriReme Medical, LLC
Industry
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
13
States / cities
Phoenix, Arizona • Rancho Mirage, California • Gainesville, Florida + 9 more