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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:18 AM EDT

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Showing 121–144 of 144 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cocoa Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

The Effects of Peanuts and Peanut Products on Glucose Control and Vascular Function

NCT01405300
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Control, Peanut
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 50 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional

The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients

NCT01842087
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Control Food, Fiber Fortified Food
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 22, 2026, 2:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Almonds, Gut Microbiome and Kids

NCT07636850
View directory record Official record
Conditions
Dysbiosis, Cardiometabolic Health Indicators
Interventions
Creamy Richards 100% Almonds! Creamy Natural Almond Butter, Cadbury Milk Chocolate Spread
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 22, 2026, 2:18 AM EDT
Recruiting Phase 1Phase 2 Interventional

Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial

NCT07161726
View directory record Official record
Conditions
Mobility Disability
Interventions
(-)-Epicatechin-rich cocoa supplementation combined with exercise training, Placebo combined with exercise training
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Fasting Mimicking Diet

NCT04150159
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
FMD Arm
Dietary Supplement
Lead sponsor
Hypertension Institute, Nashville
Other
Eligibility
35 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 22, 2026, 2:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain's Response to Chocolate

NCT03364413
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Chocolate
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Dec 8, 2023 · Synced Oct 22, 2026, 2:18 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

NCT02758990
View directory record Official record
Conditions
Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds, Dyspnea, Headache, Migraine Disorders, Arthritis, Arthralgia, Anxiety, Sleep Initiation and Maintenance Disorders, Sleep Deprivation
Interventions
Vitamin A, Vitamin B6, Vitamin C, Nicotinamide, Vitamin D3, Vitamin E, Broccoli, Spinach, Caffeine, Coffee, Axon Eyewear, Chocolate
Dietary Supplement · Other · Device
Lead sponsor
Verifomics LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2017 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Dark Chocolate (70% Cacao) on EEG Brain Waves in Vigorously Active Individuals

NCT03203824
View directory record Official record
Conditions
Healthy
Interventions
dark chocolate, non dark chocolate
Dietary Supplement · Other
Lead sponsor
Loma Linda University
Other
Eligibility
21 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Oct 22, 2026, 2:18 AM EDT
Recruiting Not applicable Interventional

Cocoa Extract for Migraine Trial

NCT06808230
View directory record Official record
Conditions
Migraine
Interventions
Cocoa extract, Cocoa extract placebo
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Epicatechin-rich Cocoa on Collagen Synthesis

NCT03214133
View directory record Official record
Conditions
Collagen Synthesis
Interventions
Epicatechin-rich cocoa dose response, Epicatechin-rich cocoa vs placebo on performance
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 25 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Flavanol-Rich Cocoa and Cerebral Blood Flow

NCT00825695
View directory record Official record
Conditions
Hypertension, Diabetes
Interventions
cocoa
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures

NCT05658757
View directory record Official record
Conditions
Blood Sugar; High, Blood Pressure, Dietary Habits
Interventions
Regular sweetened commercial foods, Allulose sweetened commercial foods, Whole and minimally processed and sweetened foods
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
20 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional

Cocoa and Metabolic Health in Prediabetes

NCT02203240
View directory record Official record
Conditions
Prediabetes
Interventions
Cocoa, Placebo
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dietary Assessment Study Via Digital Images

NCT03267004
View directory record Official record
Conditions
Diet Habit
Interventions
Dietary Assessment of Meal A using images taken by Sony Smarteyeglass, Dietary Assessment of Meal B using Images taken by Sony Smarteyeglass
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 22, 2026, 2:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Chardonnay Marc and Vascular Response

NCT05545865
View directory record Official record
Conditions
Cardiovascular Diseases, Vascular Dilation, Oxidative Stress
Interventions
Low Flavanol Cocoa Powder, High Flavanol Cocoa Powder, Vine to Bar Chocolate - 2 servings, Vine to Bar Chocolate - 1 serving, Vine to Bar Chocolate covered almonds
Other
Lead sponsor
University of California, Davis
Other
Eligibility
30 Years to 50 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Soft Tissue Therapy and Exercise on Hamstring Tightness

NCT03651141
View directory record Official record
Conditions
Hamstring Tightness, Myofascial Pain, Musculoskeletal Pain
Interventions
Neurodynamic Sliding, Myofascial Decompression, Diathermy
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 25 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity

NCT02490527
View directory record Official record
Conditions
Statin Intolerance
Interventions
Pure epicatechin capsules (50mg), Simvastatin (40mg), Placebo
Dietary Supplement · Drug · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
30 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Phytochemicals From Theobroma Cacao on Mental Energy

NCT01651793
View directory record Official record
Conditions
Mental Fatigue
Interventions
Caffeinated cocoa, Cocoa, Caffeine, Placebo
Other
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 34 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intake-dependent Effect of Cocoa Flavanol Absorption, Metabolism and Excretion in Humans

NCT03201822
View directory record Official record
Conditions
Healthy
Interventions
100 mg of Cocoa Flavanols/70 kg BW, 200 mg of Cocoa Flavanols/70 kg BW, 400 mg of Cocoa Flavanols/70 kg BW, 1000 mg of Cocoa Flavanols/70 kg BW
Other
Lead sponsor
University of California, Davis
Other
Eligibility
25 Years to 40 Years · Male only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pre- and Post-restriction Chocolate Candy Consumption

NCT02003950
View directory record Official record
Conditions
Investigate the Maladaptive Eating Behaviors of Normal Healthy Adults
Interventions
Snack Condition Specification
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 22, 2026, 2:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Strength-enhancing Effect of Whey Protein Supplementation Following Resistance Exercise in Adolescent Males

NCT02162459
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Olympia Eye Clinic
Other
Eligibility
16 Years to 19 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a Supplement to Enhance Sleep Quality and Quantity

NCT05521243
View directory record Official record
Conditions
Sleep, Sleep Disturbance, Sleep Hygiene
Interventions
Beam Organics Dream Powder, Beam Organics Dream Powder Extra Strength, Placebo
Dietary Supplement
Lead sponsor
Beam
Industry
Eligibility
24 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Watching a Television Show on the Liking of Snack Foods

NCT01694043
View directory record Official record
Conditions
Measure Grams and Kcals of Snack Foods Consumed in Each Condition
Interventions
Healthy Foods, Unhealthy Snack Foods
Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 22, 2026, 2:18 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

COcoa Supplement and Multivitamin Outcomes Study

NCT02422745
View directory record Official record
Conditions
Cardiovascular Disease, Cancer
Interventions
Cocoa extract, Multivitamin, Cocoa extract placebo, Multivitamin placebo
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
60 Years and older
Enrollment
21,442 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 22, 2026, 2:18 AM EDT