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ClinicalTrials.gov public records Last synced Oct 14, 2026, 1:15 PM EDT

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Showing 457–480 of 2,772 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive Behavior Therapy(CBT) Clear all
Completed Phase 2 Interventional Results available

Improving Therapeutic Learning in Depression: Proof of Concept

NCT02376257
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
250 mg DCS, 100 mg Modafinil, Placebo
Drug
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Self-help Books for Social Anxiety

NCT03297619
View directory record Official record
Conditions
Social Anxiety
Interventions
Mindfulness and Acceptance Workbook for Social Anxiety and Shyness, The Shyness and Social Anxiety Workbook
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse

NCT02080819
View directory record Official record
Conditions
Cocaine Dependence
Interventions
levodopa/carbidopa 400/100 BID
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Oct 14, 2026, 1:15 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Testing Pharmacological Therapies for Pregnant Smokers

NCT00224419
View directory record Official record
Conditions
Smoking, Pregnancy
Interventions
Motivational interviewing for smoking cessation, Cognitive behaviors therapy, CBT + NRT
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
2
States / cities
Durham, North Carolina • Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Phase 2Phase 3 Interventional

RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD)

NCT03827057
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Reconsolidation of Traumatic Memories (RTM), Prolonged Exposure (PE)
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Oct 14, 2026, 1:15 PM EDT
Not yet recruiting Not applicable Interventional

Deaf CBT-TS to Reduce Suicide Risk

NCT07279363
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia, Alcohol Use Disorder (AUD), Suicide Ideation
Interventions
Deaf CBT-TS
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 14, 2026, 1:15 PM EDT
Terminated Not applicable Interventional Results available

Just-In-Time Adaptive Interventions for Addictive Behaviors

NCT03538652
View directory record Official record
Conditions
Addiction
Interventions
Formative Interviews (not an intervention), Cognitive-behavioral therapy (CBT), Acceptance and commitment therapy (ACT), No intervention
Other · Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 14, 2026, 1:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Test of Target Engagement of Ambiguity Aversion

NCT06962527
View directory record Official record
Conditions
Intolerance of Uncertainty, Anxiety, Intolerance of Uncertainty; Anxiety, Depression, Anxiety
Interventions
Uncertainty-focused single session intervention, Maintaining a healthy lifestyle single session intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
25 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preoperative Cognitive Therapy for Improving Health Outcomes After TKA in High-risk Catastrophizing Subjects

NCT01772329
View directory record Official record
Conditions
Catastrophization
Interventions
Cognitive Therapy, Routine Care
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy (CBT) for PTSD in Veterans With Co-Occurring SUDs

NCT01357577
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Cognitive behavioral therapy for PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
3
States / cities
Tampa, Florida • Syracuse, New York • White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological Treatment for Alcohol Use Disorder

NCT03842670
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse, Alcohol Drinking, Alcohol Dependence
Interventions
Cognitive Behavior Therapy, Mindfulness Based Relapse Prevention
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
22 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

A Telephone Feedback System for Prevention of Chronic Pain Relapse

NCT00266773
View directory record Official record
Conditions
Chronic Pain and Relapse Prevention
Interventions
Chronic pain therapeutic interactive voice response (TIVR) system
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Phase 1Phase 2 Interventional

A Relapse Prevention Program for Reducing Relapse and Fear of Food in People With Anorexia Nervosa

NCT00627341
View directory record Official record
Conditions
Eating Disorders
Interventions
Food Exposure Therapy and Ritual Prevention with Motivational Enhancement for Relapse Prevention in Anorexia Nervosa (AN-EX/RP), Cognitive behavioral therapy (CBT)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
16 Years to 45 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2012 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Hybrid Effectiveness-Implementation Trial of Group CBT in Urban Schools

NCT02651402
View directory record Official record
Conditions
Anxiety Disorders
Interventions
FRIENDS for Life, Adapted FRIENDS, Train-the-Trainer, Train-the-Trainer Plus
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 99 Years
Enrollment
495 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Striving Towards EmPowerment and Medication Adherence (STEP-AD)

NCT02764853
View directory record Official record
Conditions
HIV
Interventions
Experimental Intervention (STEP-AD), Enhanced Treatment as Usual (E-TAU)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
2
States / cities
Miami, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Mediators and Moderators of Treatment Outcome in Recent-Onset Psychosis

NCT01570972
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder With Psychotic Features, Major Depression With Psychotic Features, Psychotic Disorder Not Otherwise Specified (NOS)
Interventions
Group Cognitive Behavioral Therapy, Multifamily Group Psychoeducation
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 35 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 14, 2026, 1:15 PM EDT
Recruiting No phase listed Observational

Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy

NCT07640802
View directory record Official record
Conditions
Irritability, Disruptive Mood Dysregulation Disorder, Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Psychotherapy
Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
8 Years to 17 Years
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Brief Cognitive Behavioral Treatment of Deployment-Related PTSD Symptoms in Primary Care Settings

NCT02290639
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Brief Cognitive Behavioral Treatment, Minimal Contact
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Lackland Air Force Base, Texas • Randolph Air Force Base, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Neurological Influences on Drug Prevention Intervention

NCT00198939
View directory record Official record
Conditions
Youths At-risk for Drug Use/Abuse
Interventions
Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 15 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 28, 2012 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional Results available

Choosing Options for Insomnia in Cancer Effectively (CHOICE): A Comparative Effectiveness Trial of Acupuncture and Cognitive Behavior Therapy

NCT02356575
View directory record Official record
Conditions
Insomnia, Cancer
Interventions
Acupuncture, Cognitive Behavior Therapy
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Oct 14, 2026, 1:15 PM EDT
Active, not recruiting Not applicable Interventional

Treatment for Migraine and Mood

NCT05576467
View directory record Official record
Conditions
Migraine, Depressive Symptoms
Interventions
MBCT-Telephone, MBCT-Video, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Amanda Shallcross
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
The Bronx, New York • Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Breaking the Cycle IV: Military PTSD (MPTSD) Treatment Study

NCT01228539
View directory record Official record
Conditions
PTSD, Anger, Aggression
Interventions
TARGET (Trauma Affect Regulation), Prolonged Exposure
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older · Male only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated May 13, 2013 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional

Therapy for Undergraduate College Students Who Binge Drink and Are Depressed

NCT01632319
View directory record Official record
Conditions
Depression, Alcohol Abuse
Interventions
Combined Motivational Interviewing and Cognitive Behavioral Therapy, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 24 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 14, 2026, 1:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Guided Group Telehealth to Deliver Evidence-based Therapeutic Care to Black College Students

NCT07237217
View directory record Official record
Conditions
Anxiety Depression
Interventions
Cognitive Behavioral Therapy (CBT) Coping Skills Training
Behavioral
Lead sponsor
Dr. Veronica Tetterton
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Prairie View, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 14, 2026, 1:15 PM EDT