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Showing 1–24 of 189 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cognitive Behavioral Therapy for Insomnia (CBT-i) Clear all
Not yet recruiting Not applicable Interventional

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

NCT07397182
View directory record Official record
Conditions
Insomnia, Mild Cognitive Impairment
Interventions
Cognitive BehavioralTherapy for Insomnia (CBT-I), SleepSMART
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers

NCT03538574
View directory record Official record
Conditions
Insomnia Chronic
Interventions
CBT-I, MAP-I
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years to 95 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2022 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Phase 3 Interventional

The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium

NCT06721819
View directory record Official record
Conditions
Delirium, Postoperative, Delirium in Old Age
Interventions
Sleep Hygiene, Brain Game, and IV Acetaminophen Intervention, Control
Combination Product · Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Improving Memory for Sleep Treatment Content With Text Messages

NCT02961400
View directory record Official record
Conditions
Sleep Wake Disorders
Interventions
PUSH text messages, PULL text messages, TranS-C, PE
Other · Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
10 Years to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Early Phase 1 Interventional

Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

NCT06281756
View directory record Official record
Conditions
Insomnia, Insomnia Chronic, Insomnia, Primary, Blood Pressure, Blood Pressure, High
Interventions
Cognitive Behavioral Treatment for Insomnia (CBT-I), Trazodone, Placebo
Behavioral · Drug · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Denver, Colorado • Hershey, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

A Conversational Agent (Cecebot) to Improve Insomnia in Stage I-III Breast Cancer Survivors

NCT06392789
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Insomnia
Interventions
Cognitive Behavior Therapy for Insomnia, Internet-Based Intervention, Medical Device Usage and Evaluation, Questionnaire Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Web-based Insomnia Treatment for Adolescent and Young Adult Cancer Survivors

NCT03279055
View directory record Official record
Conditions
Insomnia
Interventions
SHUTi
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
14 Years to 25 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2020 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional

COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL

NCT07532070
View directory record Official record
Conditions
Osteo Arthritis Knee and Hip, Low Back Pain, Insomnia
Interventions
Aerobic physical activity, CBT-I, Combined aerobic physical activity and CBT-I
Behavioral
Lead sponsor
University of Sydney
Other
Eligibility
18 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Antonio, Nevada • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Integrative Cardiac Health Project Cognitive-Behavior Therapy for Insomnia

NCT02779023
View directory record Official record
Conditions
Insomnia, Cardiovascular Risk Factor
Interventions
Cognitive-Behavior Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 1, 2026, 7:49 PM EDT
Active, not recruiting Not applicable Interventional

The Study in Outpatient Medicine Using Nudges to Improve Sleep

NCT06640023
View directory record Official record
Conditions
Inappropriate Prescribing
Interventions
Z-drug Default Quantity, Redirection + Accountable Justification
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Device Feasibility and Acceptability to Improve Insomnia in Cancer

NCT05875129
View directory record Official record
Conditions
Cancer, Insomnia Chronic
Interventions
VAVA prototype
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatments for Insomnia: Mediators, Moderators and Quality of Life

NCT02117388
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Restriction, Cognitive Behavioral Therapy, Combined Therapy
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
60 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

NCT07385105
View directory record Official record
Conditions
Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions
Cognitive behavioral Therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Insomnia: Face-to-Face Versus Telemedicine

NCT03293745
View directory record Official record
Conditions
Insomnia
Interventions
Face to Face CBT-I (F2F), Telemedicine CBT-I (TM)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Sep 1, 2026, 7:49 PM EDT
Active, not recruiting Not applicable Interventional

Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia

NCT04100057
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Neuropsychiatric Symptoms, Sleep Disturbance
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Desensitization Therapy for insomnia (DT-I)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Phase 4 Interventional

The Role of mGluR5 in CBT-I

NCT07076342
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Cognitive Behavioral Therapy for Insomnia, PET Scan with [11C]ABP688
Behavioral · Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Cognitive Behavior Therapy for Insomnia (CBT-I) in Persons With Traumatic Brain Injury (TBI)

NCT02709980
View directory record Official record
Conditions
TBI, Insomnia
Interventions
Sleep Education, Cognitive Behavior Therapy for Insomnia
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia

NCT01549899
View directory record Official record
Conditions
Insomnia
Interventions
In-person Cognitive Behavioral Therapy of Insomnia, Internet Cognitive Behavioral Therapy of Insomnia
Behavioral
Lead sponsor
Daniel J. Taylor, Ph.D.
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 1, 2026, 7:49 PM EDT
Terminated Not applicable Interventional

A Pilot Study of Digital Cognitive Behavioral Therapy for Veterans

NCT03688763
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-i)
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional

Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr

NCT07091149
View directory record Official record
Conditions
Insomnia
Interventions
CBT-I
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Phase 2 Interventional

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial

NCT06439420
View directory record Official record
Conditions
Primary Brain Tumor, Glioblastoma, Astrocytoma, Oligodendroglioma, Meningioma, Primary Central Nervous System (CNS) Lymphoma
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep in Osteoarthritis Project

NCT00592449
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Osteoarthritis
Interventions
Cognitive behavioral therapy (CBT) for insomnia, Behavioral desensitization treatment for insomnia
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
35 Years to 100 Years
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 1, 2026, 7:49 PM EDT
Recruiting Not applicable Interventional

Sleep Treatment for Teens (RCT Phase)

NCT07303959
View directory record Official record
Conditions
Sleep Problems, Suicidal Ideation, Suicidal Behavior
Interventions
Sleepio, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
14 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Piscataway, New Jersey • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 1, 2026, 7:49 PM EDT
Completed Not applicable Interventional

Cancer, Obesity/Overweight and Insomnia Study

NCT03542604
View directory record Official record
Conditions
Breast Cancer, Overweight and Obesity, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Sep 1, 2026, 7:49 PM EDT