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Showing 1–24 of 274 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cognitive Behavioral Therapy for PTSD Clear all
Recruiting Phase 2 Interventional

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

NCT05723588
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
active repetitive transcranial magnetic stimulation, sham repetitive transcranial magnetic stimulation, cognitive behavioral therapy for smoking cessation, nicotine replacement therapy
Device · Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Reducing Alcohol Use & Post-traumatic Stress Disorder (PTSD) With Cognitive Restructuring & Experiential Acceptance

NCT00760994
View directory record Official record
Conditions
Alcoholism, Stress Disorders, Post-Traumatic
Interventions
Experiential acceptance, Cognitive restructuring, No-intervention control: Nutrition information
Behavioral · Other
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Randomized Clinical Trial of Cognitive-Behavioral Treatment for Post-Traumatic Stress Disorders in Women

NCT00032617
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Prolonged Exposure, Present Centered Therapy
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older · Female only
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
13
States / cities
Denver, Colorado • Bay Pines, Florida • Decatur, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2010 · Synced Sep 22, 2026, 10:52 PM EDT
Active, not recruiting Not applicable Interventional

Examining Written Exposure Therapy Delivered to Adolescents

NCT07498257
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Written Exposure Therapy, Trauma-focused Cognitive Behavior Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 18 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 22, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Multifaceted Intervention to Restore Resilience and Overcome Risk

NCT06988787
View directory record Official record
Conditions
Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
Interventions
webSTAIR, ExpoTx, PsychoEd
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 22, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Volatility in Paranoia (VIP) Trial: An RCT of Changes in Volatility With Psychotherapy

NCT06835556
View directory record Official record
Conditions
Schizophrenia Disorders
Interventions
Cognitive Behavioral Therapy, TAU
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance

NCT00108628
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Imagery Rehearsal, Sleep and Nightmare Management
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2015 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Treatment of Posttraumatic Stress Disorder Enhanced by Virtual Reality for Individuals With PTSD and Substance Abuse

NCT00656344
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Abuse
Interventions
Cognitive behavioral treatment enhanced by virtual reality
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Effects of Mindfulness-Based Cognitive-Behavioral Conjoint Therapy on PTSD and Relationship Function

NCT01035788
View directory record Official record
Conditions
PTSD
Interventions
Mindfulness Based Cognitive Behavioral Conjoint Therapy, CBCT for PTSD - Communication Skills
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Phase 2 Interventional Results available

IOK Treatment Study

NCT01605799
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
IOK Killing Treatment, Wait list control group
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Phase 2 Interventional

DElivery of Self Training and Education for Stressful Situations-Primary Care Version

NCT01474057
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
DESTRESS-PC, Optimized Usual Primary Care PTSD treatment
Behavioral · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
Not listed
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Savannah, Georgia • Boston, Massachusetts • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional

A Mobile Health Solution for Homework During CBT

NCT04931199
View directory record Official record
Conditions
Anxiety, Depression, Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy (CBT), CBT+App
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Trauma Survivors Outcomes and Support Study IV

NCT01625416
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury, Alcohol Use, Drug Use
Interventions
Stepped Care Management
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional

Trauma and Trauma-Focused Therapy in the University of Kentucky SMART Clinic

NCT04760418
View directory record Official record
Conditions
PTSD, Opioid-use Disorder, Substance Use Disorders
Interventions
Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE)
Behavioral
Lead sponsor
Christal L Badour
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Integrated vs Sequential Treatment for PTSD and Addiction

NCT01211106
View directory record Official record
Conditions
PTSD, Substance Addiction
Interventions
Prolonged Exposure, Motivational Enhancement Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Minneapolis, Minnesota • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Violence Prevention for Adolescent Girls With Prior Maltreatment

NCT02765048
View directory record Official record
Conditions
PTSD, Depression, Aggression, Victimization
Interventions
GAIN Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
3
States / cities
Arnold, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 5, 2016 · Synced Sep 22, 2026, 10:52 PM EDT
Terminated Not applicable Interventional

Trial of Art Therapy During Cognitive Processing Therapy for PTSD

NCT02610049
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Stress Disorder, Post-Traumatic
Interventions
Cognitive Processing therapy, Art + CPT, CPT + Art Therapy
Behavioral
Lead sponsor
Hampton VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Hampton, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Trauma-Sensitive Yoga for Female Veterans With PTSD Who Experienced Military Sexual Trauma

NCT02640690
View directory record Official record
Conditions
Stress Disorders, Post-traumatic
Interventions
Trauma Center Trauma Sensitive Yoga Intervention (TCTSY), Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Decatur, Georgia • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 22, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building

NCT07217795
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
CBT + expressive writing, Wait-List Control
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

An Evaluation of MBSR and CBT for Veterans With Chronic Pain

NCT04486066
View directory record Official record
Conditions
Chronic Pain, Pain
Interventions
Mindfulness-Based Stress Reduction, Cognitive Behavioral Therapy for Chronic Pain, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 22, 2026, 10:52 PM EDT
Recruiting Not applicable Interventional

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

NCT07010757
View directory record Official record
Conditions
PTSD, Obesity
Interventions
HARPP, control arm for HARPP trial
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Group Treatment for PTSD: A Randomized Clinical Trial With Veterans

NCT01544088
View directory record Official record
Conditions
PTSD
Interventions
Group Cognitive Behavioral Treatment (GCBT), Present Centered Group Treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Male only
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced Sep 22, 2026, 10:52 PM EDT
Terminated Phase 1 Interventional Results available

Piloting Acute Care to Primary Care Linkage of Safety Net Patients

NCT01347541
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy, Motivational Interviewing, FDA-Approved Anti-Anxiety Medications, Standard Care Control
Behavioral · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 22, 2026, 10:52 PM EDT
Completed Not applicable Interventional Results available

Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial

NCT03962504
View directory record Official record
Conditions
PTSD
Interventions
trauma-focused treatment
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Charleston, South Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 22, 2026, 10:52 PM EDT