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ClinicalTrials.gov public records Last synced Oct 30, 2026, 6:12 AM EDT

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Showing 73–96 of 146 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive Behavioral Therapy for Substance Use Disorders Clear all
Completed No phase listed Observational

Mindfulness and Meditation-Based Relapse Prevention for Substance Use Disorders

NCT07417579
View directory record Official record
Conditions
Substance Use Disorders, Behavioral Health, Addiction Psychological, Addiction Disorders, Meditation, Mindfulness Based Stress Reduction, Prevention
Interventions
Mindfulness and Meditation-Based Relapse Prevention Program
Behavioral
Lead sponsor
Bout Me Healing
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Results available

Mindfulness-Based Relapse Prevention to Improve Medication Assisted Treatment Adherence and Drug-use Outcomes for Opioid Use Disorder

NCT05042388
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Mindfulness-Based Relapse Prevention - Rolling Admission (MBRP-RA), Treatment-As-Usual
Behavioral
Lead sponsor
West Chester University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Phase 1 Interventional Results available

Woebot for Substance Use Disorders

NCT04096001
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Woebot-SUDs (W-SUDs)
Device
Lead sponsor
Woebot Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women

NCT01849029
View directory record Official record
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD

NCT00680966
View directory record Official record
Conditions
Adolescent, Depression, Substance Use Disorders
Interventions
Adolescent Coping With Depression/Functional Family Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 12, 2014 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Results available

Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed Veterans

NCT00706901
View directory record Official record
Conditions
Alcohol Dependence, Dual Diagnosis, Drug Dependence
Interventions
Arm 1 GMI, Arm 2 IHMD, Arm 3 TCC
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Phase 2 Interventional

Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment

NCT01456338
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy for PTSD, Individual Addiction Counseling
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Hartford, Connecticut • Lebanon, New Hampshire • Manchester, New Hampshire + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2011 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

NCT06366633
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
Interventions
Web-TIRELESS
Behavioral
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Phase 1 Interventional Results available

Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder

NCT00946322
View directory record Official record
Conditions
Alcohol-related Disorders, Post-traumatic Stress Disorder
Interventions
Couple-Based Treatment for Alcohol Use Disorders and PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Results available

Varenicline and Motivational Advice for Smokers With Substance Use Disorders

NCT00756275
View directory record Official record
Conditions
Smoking Cessation, Nicotine Dependence
Interventions
Nicotine Replacement Treatment (NRT), varenicline, Behavioral counseling for smoking cessation
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 75 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project IntERact Study

NCT03940716
View directory record Official record
Conditions
Violence, Substance Use, Criminal Behavior
Interventions
IntERact
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 24 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Affective Management Training for Cannabis Misuse

NCT03432013
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
CUD-AMT, SUD-CBT
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 25 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Integrated Intervention Post-Sexual Assault

NCT04724746
View directory record Official record
Conditions
Substance Use Disorders, Posttraumatic Stress Disorder, Sexual Assault
Interventions
Written Exposure and Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 30, 2026, 6:12 AM EDT
Active, not recruiting Not applicable Interventional

Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)

NCT04768920
View directory record Official record
Conditions
Substance Use Disorders, Substance Use, Substance Dependence
Interventions
MI-CBT Teletx
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients

NCT00295139
View directory record Official record
Conditions
Schizophrenia, Mood Disorders, Substance Dependence
Interventions
Behavioral Treatment for Substance Abuse in SPMI (BTSAS), Supportive Treatment in Addiction Recovery (STAR), Critical Time Intervention (CTI)
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 55 Years
Enrollment
293 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
4
States / cities
Baltimore, Maryland • Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional

Treatment Outcome in CBT for Cocaine Use

NCT03538548
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
CBT-RP
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2021 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Group CBT for Depression and AOD Disorders

NCT01154309
View directory record Official record
Conditions
Depression, Substance Use
Interventions
Group CBT for Depression and AOD Disorders
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Gardena, California
Source: ClinicalTrials.gov public record
Updated Nov 16, 2011 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use

NCT04595084
View directory record Official record
Conditions
Depression, Anxiety, Substance Use, Stress, Psychological, Stress, Emotional, Alcohol Use, Unspecified, Drug Use, Covid19
Interventions
Mindfulness Based Cognitive Therapy for Resilience During COVID-19 plus CHAMindWell, Internet Cognitive Behavioral Therapy plus CHAMindWell, CHAMindWell
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Recruiting No phase listed Observational

Sensory Outcomes in Active Substance Users

NCT06639438
View directory record Official record
Conditions
Post Operative Pain, Opioid Use, Unspecified
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Recruiting Not applicable Interventional

Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke

NCT06654414
View directory record Official record
Conditions
Smoking Cessation, Depression, Anxiety, Nicotine Dependence, Gender Minority Stress
Interventions
PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Active, not recruiting Not applicable Interventional

Amplification of Positivity for Alcohol Use

NCT06030154
View directory record Official record
Conditions
Alcohol Use Disorder, Anxiety, Depression
Interventions
Cognitive Behavioral Therapy, Amplification of Positivity Therapy, Surveys and Interviews
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Therapy (CBT) for PTSD in Veterans With Co-Occurring SUDs

NCT01357577
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Cognitive behavioral therapy for PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
3
States / cities
Tampa, Florida • Syracuse, New York • White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Oct 30, 2026, 6:12 AM EDT
Completed Not applicable Interventional Results available

Safety Aid Reduction Treatment for PTSD Among Veterans

NCT04515784
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Safety Aid Reduction Treatment for PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 30, 2026, 6:12 AM EDT
Not listed No phase listed Observational

A Digital Smoking Cessation Intervention for Adults With Substance Use Disorder

NCT04419922
View directory record Official record
Conditions
Tobacco Use Disorder, Substance Use Disorders
Interventions
Smartphone Contingency Management Intervention
Behavioral
Lead sponsor
BrightView LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 30, 2026, 6:12 AM EDT