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ClinicalTrials.gov public records Last synced Oct 9, 2026, 3:59 PM EDT

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Showing 73–96 of 383 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive Behavioral Therapy for pain Clear all
Recruiting Not applicable Interventional

Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment

NCT06106191
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Mindfulness meditation, Perspectives on pain, Discussion
Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-based Intervention to Prevent Chronic Pain

NCT04848428
View directory record Official record
Conditions
Pain, Postoperative, Chronic Pain, Pain Catastrophizing, Pain, Acute
Interventions
Online mindfulness-based cognitive therapy, Online standardized education
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Improving Recovery After Orthopaedic Trauma: Cognitive-Behavioral Based Physical Therapy (CBPT)

NCT03335657
View directory record Official record
Conditions
Lower Extremity Injury
Interventions
CBPT, Education Treatment
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
633 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
8
States / cities
Tampa, Florida • Indianapolis, Indiana • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment, Pain, and Opioids

NCT05363176
View directory record Official record
Conditions
Chronic Pain
Interventions
Cognitive-Behavioral Therapy for Treatment Seeking, Pain treatment education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Pain Management Techniques for Fibromyalgia

NCT00086060
View directory record Official record
Conditions
Fibromyalgia
Interventions
Exercise regimen, Relaxation training, Standard Care
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 60 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 10, 2011 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Phase 1 Interventional

Cognitive Behavioral Therapy for Insomnia in Chronic Pain Patients

NCT00133601
View directory record Official record
Conditions
Insomnia, Chronic Pain
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
25 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2009 · Synced Oct 9, 2026, 3:59 PM EDT
Active, not recruiting Not applicable Interventional

Chronic Pain Management In Primary Care Using Behavioral Health Consultants

NCT04680000
View directory record Official record
Conditions
Chronic Pain
Interventions
Brief Cognitive Behavioral Therapy for Chronic Pain (BCBT-CP), BCBT-CP Booster
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
716 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Bethesda, Maryland • Fort Hood, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Prediction of Outcomes Following Total Knee Replacement- Pilot

NCT04328701
View directory record Official record
Conditions
Osteoarthritis, Knee, Knee Replacement
Interventions
Mindfulness-based Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation

NCT04723745
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), PTSD
Interventions
V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief, OPTIONAL At-home Exercise Program, OPTIONAL Referral to 12-week STEP-Home, OPTIONAL Clinical Referral
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Mindfulness for Pain and Suicide

NCT05286112
View directory record Official record
Conditions
Chronic Pain, Suicidal Ideation, Suicide, Attempted, Opioid Use
Interventions
Mindfulness-Based Cognitive Therapy (MBCT), Health Education
Behavioral
Lead sponsor
Canandaigua VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Not yet recruiting Not applicable Interventional

Mindfulness Therapy for Chronic Pain After Intimate Partner Violence

NCT07700355
View directory record Official record
Conditions
Chronic Pain
Interventions
Mindfulness-Based Cognitive Therapy for Trauma-Informed Pain (MBCT-TIP), Health Enhancement Program (HEP)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Terminated Not applicable Interventional

Mindfulness Meditation for Spine Surgery Pain

NCT02104349
View directory record Official record
Conditions
Meditation, Spine Surgery, Pain, Postoperative
Interventions
Mindfulness meditation
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes

NCT04433975
View directory record Official record
Conditions
Opioid-use Disorder, Medication Assisted Treatment, Chronic Pain
Interventions
Psychosocial Pain Management (PPMI), Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Combined Interventions for Treating Depression and Chronic Back Pain

NCT00158275
View directory record Official record
Conditions
Back Pain, Depression
Interventions
Cognitive behavioral therapy, Antidepressants, Problem solving therapy
Behavioral · Drug
Lead sponsor
Kaiser Permanente
Other
Eligibility
25 Years to 74 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Pain in Acute Orthopedic Injuries

NCT05552430
View directory record Official record
Conditions
Injuries, Injury Arm, Injury;Sports, Injury, Knee, Injury Wrist, Injury, Ankle, Injury Foot, Injury, Hand, Injury Finger, Injury Leg
Interventions
RelieveVRx
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Telehealth Mindfulness After Spine Surgery

NCT05698914
View directory record Official record
Conditions
Lumbar Spine Surgery, Chronic Low-back Pain, Postsurgical Pain
Interventions
Telehealth mindfulness-based intervention (MBI), Telehealth Education
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind-body Interventions for Healthy Aging

NCT03626532
View directory record Official record
Conditions
Aging
Interventions
Mindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
65 Years to 85 Years
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional

Mobile Coach for Parents of Children and Adolescents With Chronic Pain

NCT03356275
View directory record Official record
Conditions
Parents, Chronic Pain, Pediatric Disorder
Interventions
Mindfulness for Resilience in Illness: Support for Parents
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Oct 9, 2026, 3:59 PM EDT
Recruiting Not applicable Interventional

Cognitive Behavioral Theory-assisted Virtual Reality for Chronic CANcer Pain (VR-CAN)

NCT07318519
View directory record Official record
Conditions
Cancer, Cancer Pain, Chronic Cancer Pain
Interventions
VR-CAN prototype chronic cancer pain therapy -- virtual reality program delivering CBT for chronic cancer pain management, Active Control -- two-dimensional tablet-delivered intervention
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Mobile Sleep Intervention for OEF, OIF and OND Veterans

NCT02392000
View directory record Official record
Conditions
Chronic Insomnia
Interventions
WatchPAT sleep monitor, CBT-i Coach mobile app
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2018 · Synced Oct 9, 2026, 3:59 PM EDT
Not yet recruiting Not applicable Interventional

Brief Postoperative Pain Management Intervention: Meaning Making Amendment

NCT07676500
View directory record Official record
Conditions
Pain, Acute, Anxiety Acute
Interventions
Mindfulness + Meaning Making Questions, Mindfulness + Implementation Questions
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
576 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Results available

Development and Feasibility of Mindfulness Based Pain Reduction

NCT04980612
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Mindfulness Based Pain Reduction, Mindfulness Based Stress Reduction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 9, 2026, 3:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Well-being Interventions on Affect, Attention, Sleep, Social Stress and Pain Regulation

NCT01057368
View directory record Official record
Conditions
Health, Mental Health
Interventions
Day of intensive meditation practice, Mindfulness Based Stress Reduction (MBSR), Health Enhancement Program (HEP)
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
25 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
3
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 5, 2014 · Synced Oct 9, 2026, 3:59 PM EDT