Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 4, 2026, 7:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 357 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Active, not recruiting Not applicable Interventional

Treatments in Women Veterans With Insomnia and PTSD

NCT05683132
Conditions
Insomnia, PTSD, Women Veterans
Interventions
Trauma-Informed CBT-I, PTSD Psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
West Los Angeles, California
Conditions
Sleep, Insomnia, Pain, Quality of Life
Interventions
Brief Behavioral Therapy for Insomnia (BBTI)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

NCT03954210
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Completed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Three Lucid Dreaming and Sleep Hygiene Techniques

NCT03913988
Conditions
Anxiety
Interventions
Lucid Dream, Stress Reduction, Sleep Hygiene Techniques
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Conditions
Insomnia Chronic
Interventions
CBT-I, MAP-I
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years to 95 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Insomnia
Interventions
Partner-Assisted Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Conditions
Complex Insomnia
Interventions
eszopiclone, Brief behavioral therapy for insomnia
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Insomnia Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Passive Body Heating (PBH)
Behavioral · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Conditions
Insomnia, Fibromyalgia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Cognitive Behavioral Therapy for Pain (CBT-P)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Insomnia
Interventions
cognitive behaviorial therapy -Insomnia
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Rochester, Minnesota
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for insomnia (CBTi-CB-TM), Sleep Hygiene Education (SHE-TM)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Results available

Mindfulness and CBT for Sleep

NCT04736056
Conditions
Hematologic Malignancy
Interventions
Mindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Sleep Wake Disorders, Sleep Disturbance, Sleep-Related Impairment
Interventions
Transdiagnostic Sleep and Circadian Intervention (TranS-C), adapted for cardiac rehabilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Insomnia Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia, Passive Body Heating (PBH)
Behavioral · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education, Sleep Education enhanced with Nightmare Education
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Asthma, Insomnia Chronic
Interventions
Internet-based CBT-I
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Gastroesophageal Reflux Disease
Interventions
Web-based CBTI
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Insomnia, PTSD
Interventions
The ABC of Insomnia (Acceptance and the Behavioral Changes to treat Insomnia), Cognitive-Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Sepulveda, California • Miami, Florida
Conditions
Adverse Childhood Experiences, Vascular Dilatation, Sleep, Sleep Disturbance, Psychosocial Stressor, Psychological Trauma, Endothelial Dysfunction, Inflammation, Oxidative Stress
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-i)
Behavioral
Lead sponsor
Nathaniel Jenkins
Other
Eligibility
18 Years to 29 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Sleep Disturbance
Interventions
Sleep Program, Waitlist
Behavioral · Other
Lead sponsor
University of Southern Denmark
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Completed Not applicable Interventional Results available

Telemedicine Management of Chronic Insomnia

NCT01686438
Conditions
Sleep Initiation and Maintenance Disorders, Post-Traumatic Stress Disorders
Interventions
Cognitive behavioral therapy for insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers Results available

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

NCT02488863
Conditions
Musculoskeletal Pain, Pain, Chronic
Interventions
MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires, Physical and Cognitive Function Testing
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
4
States / cities
Gainesville, Florida
Active, not recruiting Not applicable Interventional

Perinatal Research on Improving Sleep and Mental Health

NCT05596318
Conditions
Insomnia, Depression
Interventions
Digital CBT-I, Digital SHE
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Francisco, California