Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 22, 2026, 9:39 PM EDT

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Showing 49–72 of 672 matching trials from the live ClinicalTrials.gov search.
Conditions
Psychological Trauma, Mental Health
Interventions
COAST-IS, TF-CBT Learning Collaborative
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Acute Pain
Interventions
cognitive interview
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Not listed Not applicable Interventional Accepts healthy volunteers

Stress Management and Resiliency Training for Physicians

NCT03570853
Conditions
Burnout, Professional, Stress
Interventions
SMART-3RP
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Newton, Massachusetts
Conditions
Insomnia, PTSD
Interventions
The ABC of Insomnia (Acceptance and the Behavioral Changes to treat Insomnia), Cognitive-Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Sepulveda, California • Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers

ACT with NMOSD Patients and Caregivers Pilot Study

NCT05840055
Conditions
NMO Spectrum Disorder
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Suicide Risk, Suicide Attempt, Treatment Response
Interventions
Brief Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Depression in Old Age
Interventions
On-site AE, At-home AE, Social Engagement (SE)
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Conditions
Opioid-use Disorder
Interventions
Contingency Management, Brief Motivational Interviewing + Substance Free Activities + Mindfulness
Behavioral
Lead sponsor
Karen Derefinko, PhD
Other
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Enrolling by invitation Not applicable Interventional

Mild Cognitive Impairment and Neuromodulation

NCT07691918
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Low intensity focused ultrasound, Sham (No Treatment)
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
55 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Roanoke, Virginia
Conditions
Anxiety Disorders
Interventions
Project EMPOWER, Being Brave Parent Education, Sharing Feelings
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed No phase listed Observational Accepts healthy volunteers

Linus Health CDS Retrospective Validation Study

NCT05900310
Conditions
Cognitive Impairment, Motor Disorders, Dementia
Interventions
Core Cognitive Evaluation (CCE)
Diagnostic Test
Lead sponsor
Linus Health, Inc.
Industry
Eligibility
55 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Insomnia, Mental Health Functioning, Physical Health Functioning
Interventions
Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Atherosclerosis, Stress, Inflammation
Interventions
Stress Reduction
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
30 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Cancer
Interventions
Social Cognitive Theory, goal system theory
Behavioral
Lead sponsor
Robert H. Friedman
Other
Eligibility
18 Years and older
Enrollment
1,049 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Components Study of REAL Essentials

NCT06112912
Conditions
Components of REAL Essentials
Interventions
REAL Essentials Advance
Other
Lead sponsor
Mathematica Policy Research, Inc.
Other
Eligibility
14 Years to 19 Years
Enrollment
1,301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Princeton, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers

Project THINK: Trial of a Brief Cognitive Restructuring Intervention

NCT05720741
Conditions
Anxiety, Depression, Stress
Interventions
Project THINK, Project SHARE
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
10 Years to 16 Years
Enrollment
597 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Suspended Not applicable Interventional Accepts healthy volunteers

Virtual Reality to Reduce Pre-Operative Anxiety

NCT04268914
Conditions
Virtual Reality, Augmented Reality, IV Stick, Mask Induction, Ambulatory Surgery, Pain, Anxiety
Interventions
Oculus Go VR, Mira Prism VR
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 21 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Depression
Interventions
Cognitive behavioral therapy plus social cognitive training (CBTSCT)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
13 Years to 17 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Breast Cancer
Interventions
Taking Charge during Treatment (TCT) Intervention
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Wauwatosa, Wisconsin
Conditions
Primary Malignant Brain Tumors
Interventions
CAU+ (Enhanced Care as Usual), Beating the Blues, SmartCare
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Recruiting Phase 2 Interventional

Deep Sleep in Older Adults

NCT07316153
Conditions
Insomnia, Insomnia Chronic
Interventions
SleepSpaceRx CBT-I-IoT-AI, SleepEZ CBTi, Sleep Hygiene IoT
Behavioral
Lead sponsor
Proactive Life Inc
Industry
Eligibility
55 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Well-Being, Psychological, Work Injury, Musculoskeletal Pain, High Frequency Heart Rate Variability, Burnout, Mindfulness, Self-Compassion, Acceptance and Commitment Therapy, Heart Rate Variability
Interventions
Eastern Principles Acceptance and Commitment Therapy for Nurses and Nursing Aids (EPACT NNA), Acceptance and Commitment Therapy for Nurses and Nursing Aids (ACT NNA)
Behavioral
Lead sponsor
Bowling Green State University
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Bowling Green, Ohio
Conditions
Diabetes Mellitus, Type 2
Interventions
Enhanced Engagement Protocol for CTH (EE-CTH), Connection to Health (CTH)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
725 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Francisco, California