- Conditions
- Cognitive Decline, Cardiovascular Diseases, Cognitive Dysfunction, Cognitive Impairment, Mild Cognitive Impairment
- Interventions
- Mind, Move
- Behavioral
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 65 Years and older · Female only
- Enrollment
- 253 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
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Showing 25–48
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- Conditions
- Mild Cognitive Impairment, Cognitive Disorders
- Interventions
- 5-month aerobic exercise intervention
- Behavioral
- Lead sponsor
- Wake Forest University
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Dementia, Postoperative Delirium (POD), Postoperative Neurocognitive Disorder, Major Adverse Cardiac and Cerebrovascular Events, Perioperative Complications, Postoperative Cognitive Decline
- Interventions
- Personalized CPC Prehabilitation, Cognitive Training, Meditation, Daily Exercise, Enhanced Social Support, Proactive Bundle Interventions, Pre-operative Standard of Care, Intra-operative Standard of Care
- Other · Behavioral · Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 1,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 5
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Obesity, Physical Activity
- Interventions
- Peer-Education Family Fitness Program (PE-FFP), Family Fitness Program (FFP)
- Behavioral
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Other
- Eligibility
- 11 Years to 14 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2018
- U.S. locations
- 4
- States / cities
- Champaign, Illinois • Mahomet, Illinois • Urbana, Illinois
- Conditions
- Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With No Loss of Consciousness
- Interventions
- Cognitive Rehab, Brainworks, Informational Handout/Provider Visits
- Behavioral
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 143 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Schizophrenia
- Interventions
- D-cycloserine, Placebo, Cognitive Remediation
- Drug · Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Effect of Exercise on Cognitive Function
- Interventions
- Intensive Exercise, Home Exercise, Cognitive Training, Health Education
- Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 55 Years to 75 Years
- Enrollment
- 96 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Cystic Fibrosis, Fatigue
- Interventions
- CF Wellness Program Sessions
- Other
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Seattle, Washington
- Conditions
- Multiple Sclerosis
- Interventions
- Seated Physical activity INtervention for persons with MS, "SPIN" program- Intervention Condition, WEllness for Longevity Living with MS (WELL)- Control Condition
- Behavioral
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Mild Cognitive Impairment, Memory Disorders, Mild Dementia, Impaired Cognition, Mild Cognitive Disorder, Amnestic Disorder, Dementia and Amnestic Conditions, Poor Short-term Memory, Memory Impairment, Mild Neurocognitive Disorder
- Interventions
- Computerized brain fitness training, Yoga, Wellness Education, Support Group (patient and partner), Cognitive Rehabilitation
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Older Adults With Cognitive Decline, Older Adults, AI-Based Fitness, Wearables, Cognitive Decline, Physical Activity, Physical Inactivity
- Interventions
- Fitness app for self-efficacy, Social network via app for social support, Health education app targeting outcome expectations
- Other
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 2
- States / cities
- Knoxville, Tennessee
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress, Adolescent Development, Family Research
- Interventions
- CookingMatters, Parent Education, Physical Activity, Health Education, Mindfulness-based Stress Reduction, Brief Mindfulness Intervention
- Behavioral
- Lead sponsor
- Colorado State University
- Other
- Eligibility
- 12 Years to 15 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 2
- States / cities
- Fort Collins, Colorado
- Conditions
- Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Obesity-Related Malignant Neoplasm
- Interventions
- Behavioral Dietary Intervention, Educational Intervention, Health Promotion and Education, Internet-Based Intervention, Interview, Medical Device Usage and Evaluation, Mindfulness Relaxation, Physical Performance Testing, Questionnaire Administration
- Behavioral · Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- La Crosse, Wisconsin
- Conditions
- Wellness, Self Compassion, Burnout, Anxiety, Depression
- Interventions
- App-based bundled mental fitness intervention, App-based wellness module collection
- Other
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Stepped Care Cognitive Behavioral Therapy, Exercise, Physical Activity, Anxiety Depression
- Interventions
- Stepped Care Mental Health Counseling, Exercise Program
- Behavioral
- Lead sponsor
- Colorado State University
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Fort Collins, Colorado
- Conditions
- Parkinson's Disease, Mild Cognitive Impairment
- Interventions
- Brain Fitness, InSight, Active Control
- Behavioral
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 21 Years to 90 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Survivors of Childhood Cancer
- Interventions
- 12 Week Exercise Intervention, Cognitive Training Intervention, Mindfulness practice intervention
- Other
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Breast Cancer, Sedentary Lifestyle
- Interventions
- Common intervention components for Lifestyle
- Behavioral
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 7 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Knoxville, Tennessee
- Conditions
- Exercise Response
- Interventions
- Aerobic Exercise Training, Cognitive Component
- Behavioral · Other
- Lead sponsor
- Molly S. Bray
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 3,773 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2017
- U.S. locations
- 2
- States / cities
- Birmingham, Alabama • Houston, Texas
- Conditions
- MomZing Exercise Videos Online, Standard Exercise DVD
- Interventions
- MomZing Web Program, Standard Exercise DVD
- Behavioral
- Lead sponsor
- University of Hawaii
- Other
- Eligibility
- 18 Years to 45 Years · Female only
- Enrollment
- 499 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 2
- States / cities
- Honolulu, Hawaii
- Conditions
- Symptom Management, Young Adult Cancer, Physical Activity, Gaming, Behavior Change Interventions
- Interventions
- PAfitME™
- Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years to 39 Years
- Enrollment
- 89 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Healthy Adults
- Interventions
- Body-Brain Trainer, Body Trainer, Brain Trainer, Expectancy Matched Control
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 55 Years to 80 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent, Aphasia Following Cerebral Infarction, Aphasia Following Nontraumatic Intracerebral Hemorrhage
- Interventions
- High-intensity physical exercise, Low-intensity physical exercise
- Behavioral
- Lead sponsor
- University of California, Berkeley
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 4
- States / cities
- Berkeley, California • Hayward, California • San Francisco, California
- Conditions
- Smoking
- Interventions
- Cognitive Behavioral Counseling, Mobile Contingency Management, Bupropion, Transdermal nicotine patch, Nicotine polacrilex, Nicotine lozenge
- Behavioral · Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Durham, North Carolina