- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Computerized Cognitive Skill Training, CRT and Social Cognition
- Behavioral
- Lead sponsor
- Nathan Kline Institute for Psychiatric Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 448 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
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Showing 1–24
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- Conditions
- Cognitive Impairment
- Interventions
- Cognitive Training
- Behavioral
- Lead sponsor
- Karen Seal
- Federal
- Eligibility
- 18 Years to 40 Years · Male only
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Psychosis
- Interventions
- CLUES, therapy and computer games
- Behavioral
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 16 Years to 25 Years
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Chronic Schizophrenia
- Interventions
- Cognitive remediation therapy, COMT Genotyping
- Behavioral · Genetic
- Lead sponsor
- Manhattan Psychiatric Center
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 142 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2016
- U.S. locations
- 1
- States / cities
- Wards Island, New York
- Conditions
- Schizophrenia, Schizoaffective Disorder, Major Depression, Bipolar Disorder, Anxiety Disorder
- Interventions
- Thinking Skills for Work Program, Supported Employment
- Behavioral
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Manchester, New Hampshire
- Conditions
- Glioma, Brain Tumor, Primary
- Interventions
- CogMed®
- Behavioral
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
- Interventions
- Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST), Chorus Participatory Text Messaging Program, Healthy Living Group (HLG)
- Behavioral
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Epilepsy, Traumatic, Brain Injuries, Traumatic
- Interventions
- Home Based Self-management and Cognitive Training Changes lives in post traumatic epilepsy (HOBSCOTCH-PTE), HOBSCOTCH-PTE for Caregivers
- Behavioral
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Aging, Inflammation, Cognitive Remediation, Cognitive Dysfunction, Postviral Syndrome, Digital Medicine
- Interventions
- Computerized Cognitive Remediation, Alternative Computer Activities
- Other
- Lead sponsor
- Cutter Lindbergh
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Multiple Sclerosis, Neurological Disorder
- Interventions
- tDCS stimulation
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Mild Traumatic Brain Injury
- Interventions
- Tolcapone, Placebo
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2021
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Schizophrenia
- Interventions
- Targeted cognitive training, Computer control, Bridging groups, Health and wellness groups
- Behavioral
- Lead sponsor
- National Institute of Mental Health (NIMH)
- NIH
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 9
- States / cities
- New Haven, Connecticut • Atlanta, Georgia • Augusta, Georgia + 6 more
- Conditions
- Multiple Sclerosis
- Interventions
- Prospective Memory Intervention, Educational
- Behavioral
- Lead sponsor
- Trinity Health Of New England
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 35 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Hartford, Connecticut
- Conditions
- Schizophrenia
- Interventions
- Visual Training
- Behavioral
- Lead sponsor
- Rutgers, The State University of New Jersey
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Piscataway, New Jersey
- Conditions
- HIV-associated Neurocognitive Dysfunction
- Interventions
- Computerized plasticity-based adaptive cognitive training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 25 Years to 60 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Schizophrenia
- Interventions
- D-cycloserine, Placebo, Cognitive Remediation
- Drug · Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Mild Cognitive Impairment
- Interventions
- Computer-based training for Mild Cognitive Impairment (MCI)
- Procedure
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 65 Years to 90 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Sensory Information Processing Training, Active Control Training
- Behavioral
- Lead sponsor
- VA Connecticut Healthcare System
- Federal
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Schizophrenia
- Interventions
- Auditory Cognitive Training, Visual Cognitive Training
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury
- Interventions
- Methylphenidate Hydrochloride 20 mg, Placebo Capsule, Galantamine 12 mg
- Drug
- Lead sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 7
- States / cities
- San Diego, California • Boston, Massachusetts • Manchester, New Hampshire + 4 more
- Conditions
- Mental Illness, Schizophrenia, Depression, PTSD, Bipolar Disorder
- Interventions
- Cognitive Remediation, Nintendo Brain Age
- Behavioral
- Lead sponsor
- VA Connecticut Healthcare System
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Asperger's Syndrome, Pervasive Developmental Disorder
- Interventions
- Cognitive Enhancement Therapy, Enriched Supportive Therapy
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 16 Years to 45 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2017
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Brain Basics, Brain Training
- Behavioral
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 68 Years
- Enrollment
- 194 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 9
- States / cities
- Stamford, Connecticut • Brooklyn, New York • New York, New York + 2 more
- Conditions
- Schizophrenia
- Interventions
- Cognitive Remediation, Cognitive Behavioral Social Skills Training, Retest in Health Controls
- Behavioral · Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2007
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota