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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Cognitive Remediation Therapy Clear all
Completed Not applicable Interventional Results available

Specialized Treatment Early in Psychosis (STEP)

NCT00309452
View directory record Official record
Conditions
Schizophrenia and Disorders With Psychotic Features
Interventions
Cognitive Behavioral Group Therapy, Cognitive remediation, Medications, MFG, Assertive case management, Treatment as Usual in the community
Behavioral · Drug · Other
Lead sponsor
Yale University
Other
Eligibility
16 Years to 45 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Brain-Training Treatment for Long COVID in Older Adults

NCT05705193
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome
Interventions
NeuroFlex (computerized gamified tasks)
Other
Lead sponsor
UConn Health
Other
Eligibility
60 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder

NCT03170453
View directory record Official record
Conditions
Autistic Disorder, Autism Spectrum Disorder, Asperger Syndrome, Pervasive Developmental Disorder
Interventions
Cognitive Enhancement Therapy, Enriched Supportive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
16 Years to 45 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 27, 2026, 5:01 PM EDT
Not listed Not applicable Interventional

Relation of Catechol-O-methyltransferase (COMT) Genotype and Response to Cognitive Remediation Schizophrenia

NCT00664274
View directory record Official record
Conditions
Chronic Schizophrenia
Interventions
Cognitive remediation therapy, COMT Genotyping
Behavioral · Genetic
Lead sponsor
Manhattan Psychiatric Center
Other
Eligibility
18 Years to 55 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Wards Island, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Sep 27, 2026, 5:01 PM EDT
Active, not recruiting Not applicable Interventional

Promoting Activity and Cognitive Enrichment in Schizophrenia (PACES)

NCT04143126
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive Enhancement Therapy, Enriched Supportive Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Hoarding Older Adults

NCT01227057
View directory record Official record
Conditions
Compulsive Hoarding
Interventions
Cognitive Rehabilitation and Exposure Therapy for Compulsive Hoarding, Case Management
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Treatment to Enhance Cognition in Bipolar Disorder

NCT01470781
View directory record Official record
Conditions
Bipolar Disorder, Psychosis
Interventions
BrainWorks, Computer Control
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Neuroplasticity-Based Cognitive Remediation for Chemotherapy-Related Cognitive Impairment

NCT04230863
View directory record Official record
Conditions
Cancer Survivors, Chemotherapy-related Cognitive Impairment
Interventions
Neuroplasticity-based Computerized Cognitive Remediation
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
35 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Cognitive Remediation Outcomes in Schizophrenia

NCT02105779
View directory record Official record
Conditions
Schizophrenia, Psychosis
Interventions
Targeted Cognitive Training, Social Cognitive Training
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Cognitive Training to Enhance VA Work Program Outcomes

NCT00829400
View directory record Official record
Conditions
Mental Illness, Schizophrenia, Depression, PTSD, Bipolar Disorder
Interventions
Cognitive Remediation, Nintendo Brain Age
Behavioral
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 19, 2018 · Synced Sep 27, 2026, 5:01 PM EDT
Withdrawn Not applicable Interventional

Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Interictal Dysfunction in Epilepsy

NCT02950506
View directory record Official record
Conditions
Epilepsy
Interventions
transcranial direct current stimulation, Cognitive Remediation Therapy
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 27, 2026, 5:01 PM EDT
Terminated Not applicable Interventional

Impact of Individual Cognitive Remediation for Parkinson's Disease

NCT03622840
View directory record Official record
Conditions
Cognitive Impairment, Parkinson Disease
Interventions
Cognitive Remediation
Behavioral
Lead sponsor
New York Institute of Technology
Other
Eligibility
40 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Cognitive Remediation for Schizophrenia

NCT00295048
View directory record Official record
Conditions
Schizophrenia
Interventions
Computer Assisted Cognitive Remediation (CACR)
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
Baltimore, Maryland • Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Sep 27, 2026, 5:01 PM EDT
Completed No phase listed Observational Results available

Optimizing Cognitive Remediation

NCT04395157
View directory record Official record
Conditions
Schizophrenia, Stress Disorders, Post-Traumatic, Generalized Anxiety Disorder, Mood Disorders
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

GAME Veterans With PTSD Using Computer-Based Cognitive Training

NCT01087775
View directory record Official record
Conditions
Cognitive Impairment
Interventions
Cognitive Training
Behavioral
Lead sponsor
Karen Seal
Federal
Eligibility
18 Years to 40 Years · Male only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2019 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson's Disease

NCT04955275
View directory record Official record
Conditions
Parkinson Disease
Interventions
Cognitive Remediation Therapy Program (BrainHQ)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
40 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Feasibility of Combining Family and Cognitive Therapy to Prevent Chronic Anorexia

NCT02054364
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
FBT and CRT, FBT and art therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
11 Years to 19 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic

NCT04952532
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Neuropsychological Educational Approach to Cognitive Remediation (NEAR, termed Cognitive Remediation plus Bridging)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 27, 2026, 5:01 PM EDT
Not listed Not applicable Interventional

Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)

NCT04321759
View directory record Official record
Conditions
Schizophrenia and Related Disorders
Interventions
Cognitive Enhancement Therapy, Social Skills Training
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
378 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
5
States / cities
Hartford, Connecticut • Portland, Maine • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Computerized Exercise Training for Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya

NCT02141022
View directory record Official record
Conditions
Multiple Sclerosis, Cognitive Deficits, Gilenya Modifying Therapy for MS
Interventions
plasticity-based computerized cognitive remediation program, Gileyna
Other · Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 9, 2016 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional

What the Nose Knows: Hedonic Capacity, Psychosocial Interventions and Outcomes in Schizophrenia

NCT05282186
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive Enhancement Therapy, Social Skills Training
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Phase 2 Interventional Results available

Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment

NCT01410110
View directory record Official record
Conditions
Substance Abuse, Substance Dependence, Cognitive Impairment
Interventions
Cognitive Training + Work Therapy, Work Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Sep 27, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavior Therapy and Work Outcome

NCT00810355
View directory record Official record
Conditions
Schizophrenia
Interventions
Support Group, Cognitive Behavior Therapy, Cognitive Remediation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Sep 27, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk

NCT05131035
View directory record Official record
Conditions
Psychosis, Prodromal Schizophrenia, Prodromal Symptoms
Interventions
SCORES (Specific COgnitive Remediation with Support)
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
14 Years to 20 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 27, 2026, 5:01 PM EDT