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ClinicalTrials.gov public records Last synced Oct 28, 2026, 2:04 AM EDT

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Showing 193–216 of 408 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive Task Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Brain Health Study: A Pragmatic, Patient-Centered Trial

NCT05905796
View directory record Official record
Conditions
Dementia, Alzheimer Disease
Interventions
Brain Health Assessment
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
1,261 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
3
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Applying a Person-Centered Approach to Enhance Cognitive Training in Senior Living Community Residents With Mild Cognitive Impairment

NCT03292705
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
PEP, CCI
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Attention and Wellbeing Using Digital Therapeutics

NCT06397469
View directory record Official record
Conditions
Aging, MCI, Cognitive Decline
Interventions
MediTrain, Worder
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 99 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Benefits of Naps on Cognitive, Emotional, and Motor Learning in Preschoolers

NCT03285880
View directory record Official record
Conditions
Sleep
Interventions
Napping
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
33 Months to 60 Months
Enrollment
361 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 28, 2026, 2:04 AM EDT
Recruiting Phase 2Phase 3 Interventional

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

NCT06273527
View directory record Official record
Conditions
Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Interventions
COGENT, Sham Program
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 28, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants

NCT05929898
View directory record Official record
Conditions
Motivation, Memory, Self-regulation
Interventions
Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Active, not recruiting Not applicable Interventional

tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity

NCT05225233
View directory record Official record
Conditions
Obesity
Interventions
Sham Transcranial Direct Current Stimulation (tDCS), Active Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Results available

The Effects of Dual Task Training in Individuals With Parkinson's Disease

NCT02538029
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Dual Task Group, Single Task Group
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 28, 2026, 2:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Mental Flexibility

NCT04135001
View directory record Official record
Conditions
Anger, Hostility
Interventions
HBM Training, Placebo Training
Behavioral · Other
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Results available

Home-Based Dual-Task Training for Older Adults

NCT05108246
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Dual-Task Exercise Training
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 28, 2026, 2:04 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?

NCT06616363
View directory record Official record
Conditions
POTS - Postural Orthostatic Tachycardia Syndrome
Interventions
Questionnaires to be competed, Provide list of medication and lifetime events, Use phone App to record new life events, Will wear an activity monitor, Periodic 24-hour urine sodium check, A fMRI scan, A bedside tilt test will be performed, IV placed to collect blood samples, Stool Sample
Behavioral · Device · Other + 1 more
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 21 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Results available

Cognitive Fitness for Depression in Older Adults

NCT04790630
View directory record Official record
Conditions
Depression Mild, Depressive Disorder, Major, Mild Cognitive Impairment
Interventions
Computerized Cognitive Remediation of Executive Functioning (CCR-EF), Active Control
Other
Lead sponsor
UConn Health
Other
Eligibility
60 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

D2D Normative Data for Remote Assessments

NCT03206775
View directory record Official record
Conditions
Cognition
Interventions
Cognitive Assessments (Phase 1), Cognitive Battery A (Phase 2), Cognitive Battery B (Phase 2), Cognitive Battery C (Phase 2)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 80 Years
Enrollment
1,271 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
San Francisco, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Results available

Dual-task Augmented Reality for PD DBS

NCT06418152
View directory record Official record
Conditions
Parkinson's Disease, Deep Brain Stimulation
Interventions
Multi-modal treatment
Behavioral
Lead sponsor
Jay Alberts
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Dysfunction In Parkinson's

NCT02468804
View directory record Official record
Conditions
Parkinson's
Interventions
rTMS, Sham TMS
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 90 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Phase 3 Interventional Results available

Preventing Cognitive Decline in African Americans With Mild Cognitive Impairment

NCT01299766
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Behavioral Activation (BA), Supportive Therapy (ST)
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
65 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2018 · Synced Oct 28, 2026, 2:04 AM EDT
Enrolling by invitation Not applicable Interventional

Understanding Freezing of Gait Using Brain Signals and Virtual Reality

NCT07092995
View directory record Official record
Conditions
Parkinson&Amp;#39;s Disease, Freezing of Gait, Freezing of Gait Symptoms in Parkinson&Amp;#39;s Disease
Interventions
VR Freezing Task, Dual Task, External Cueing
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

NCT05949177
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries
Interventions
Graded Exposure and Mindfulness Meditation, Waitlist Control
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 28, 2026, 2:04 AM EDT
Not yet recruiting No phase listed Observational

REWIRE: Real-world Engagement With Interventional and Rejoyn Effectiveness

NCT07792252
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Rejoyn, Cognitive Behavioral Therapy (CBT) exercises
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Greenwich, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional

Programming Aquatic Therapy for POTS

NCT07182578
View directory record Official record
Conditions
Postural Orthostatic Tachycardia Syndrome (POTS)
Interventions
Aquatic Occupational Therapy
Other
Lead sponsor
California State University, Dominguez Hills
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cerebellar Involvement in Cognitive Sequencing

NCT06108336
View directory record Official record
Conditions
Effects of Cerebellar Stimulation on Brain Activation
Interventions
TMS during sequence-demanding task, No TMS during sequence-demanding task, TMS during non-sequence-demanding task, No TMS during non-sequence-demanding task
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 28, 2026, 2:04 AM EDT
Not listed Not applicable Interventional

Cognitive Control Training as an Adjunct to Behavioral Activation Therapy in the Treatment of Depression

NCT01694719
View directory record Official record
Conditions
Depression
Interventions
Brief Behavioral Activation Treatment for Depression, Cognitive Control Training
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 27, 2012 · Synced Oct 28, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Speech Perception With High Cognitive Demand

NCT04698356
View directory record Official record
Conditions
Speech Intelligibility, Aging
Interventions
Auditory-cognitive training paradigm
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 30 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Oct 28, 2026, 2:04 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults

NCT07727577
View directory record Official record
Conditions
Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
Interventions
High-Intensity Interval Training
Behavioral
Lead sponsor
Colby-Sawyer College
Other
Eligibility
55 Years to 79 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New London, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 28, 2026, 2:04 AM EDT