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Showing 409–432 of 1,073 matching trials from the live ClinicalTrials.gov search.
Recruiting Not applicable Interventional Accepts healthy volunteers

Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease

NCT04800588
Conditions
Alzheimer Disease, Cognitive Decline, Aging
Interventions
California Cognitive Assessment Battery
Diagnostic Test
Lead sponsor
Neurobehavioral Systems, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Berkeley, California
Completed No phase listed Observational Accepts healthy volunteers

Validation of Brain Function Assessment Algorithm for mTBI/Concussion

NCT03671083
Conditions
Brain Injuries, Traumatic, Concussion, Mild, Concussion, Severe, Concussion, Intermediate, Concussion, Brain
Interventions
BrainScope Ahead 300iP
Device
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
13 Years to 25 Years
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
5
States / cities
Fayetteville, Arkansas • Miami, Florida • East Lansing, Michigan + 2 more
Completed Phase 2 Interventional Results available

Web-based Interpretation Training For Anxiety

NCT02382003
Conditions
Anxiety
Interventions
Positive Cognitive Bias Modification - Interpretation, 50/50 Cognitive Bias Modification - Interpretation, Anxious Imagery Prime, Neutral Imagery Prime
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
807 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed No phase listed Observational Accepts healthy volunteers Results available

Impact of Hyperarousal on Simple and Complex Cognitive Task Performance Among Insomnia Sufferers

NCT02290405
Conditions
Insomnia, Primary Insomnia, Chronic Insomnia
Interventions
Multiple Sleep Latency Test (MSLT)
Behavioral
Lead sponsor
Jack Edinger, PhD
Other
Eligibility
21 Years to 80 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Trichotillomania
Interventions
Acceptance enhanced behavior therapy (AEBT), Psychoeducation and supportive therapy (PST)
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Clinical High Risk for Psychosis
Interventions
Targeted Cognitive Training, Computer Games
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
15 Years to 30 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
Interventions
tDCS in Youth with mild traumatic brain injury
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 15 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Suicidal Ideation, Suicide, Suicide Attempt
Interventions
Ecological momentary assessment (EMA), Treatment as usual (TAU), Brief skills sessions plus EMI skills practice prompts
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Conditions
Healthy Volunteers
Interventions
Rhodiola rosea (low dose), Rhodiola rosea (high dose), Placebo capsules
Dietary Supplement
Lead sponsor
Jacksonville State University
Other
Eligibility
18 Weeks to 40 Weeks
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Jacksonville, Alabama
Conditions
Breast Cancer
Interventions
Mindfulness-Based Therapy for Insomnia with Cognitive-Behavioral Symptom Coping Skills
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Prince Frederick, Maryland • Henderson, North Carolina • Laurinburg, North Carolina + 1 more
Conditions
Combat Disorders, Post-traumatic Stress Disorder
Interventions
Prolonged Exposure Therapy (PE), Relaxation Training (RT)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older · Male only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a Supplement to Promote Brain Health

NCT05520424
Conditions
Memory Deficits, Cognitive Change, Stress
Interventions
The Daily Supplement
Dietary Supplement
Lead sponsor
Parable
Industry
Eligibility
30 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Conditions
Breast Cancer, Colorectal Cancer, Bladder Cancer, Lung Cancer
Interventions
Semi-structured interview
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

An Online Study of the Reliability of the Brain Performance Test (BPT)

NCT02403609
Conditions
Healthy Volunteers
Interventions
BPT, Computerized Assessment
Other
Lead sponsor
Lumos Labs, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,357 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
San Francisco, California
Conditions
Major Depressive Disorder
Interventions
Neuropsychological Educational Approach to Cognitive Remediation (NEAR, termed Cognitive Remediation plus Bridging)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Not listed Not applicable Interventional Accepts healthy volunteers

EndeavorOTC® Research Study in College Students

NCT06376032
Conditions
Attention, Cognition, University Students
Interventions
EndeavorOTC®
Device
Lead sponsor
Akili Interactive Labs, Inc.
Industry
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Cheektowaga, New York • Putney, Vermont
Completed Not applicable Interventional

Managing Diabetes Mindfully Study

NCT01796834
Conditions
Diabetes Mellitus
Interventions
Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Bloomington, Minnesota
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Cognition and Neuroplasticity Sedentary Adults After 8 Weeks of Aerobic Exercise

NCT03804528
Conditions
Sedentary Behavior
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
55 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Intervention in Depression

NCT06080932
Conditions
Depression, Ketosis
Interventions
Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Completed No phase listed Observational Accepts healthy volunteers

Neurotrack Test Validation Protocol

NCT02608021
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
60 Years to 85 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Depression
Interventions
Cognitive Training, Sham Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Repetitive Transcranial Magnetic Stimulation Equipment Testing and Pilot Study

NCT02231892
Conditions
Healthy Volunteer
Interventions
TMS
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 55 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Terminated No phase listed Observational Accepts healthy volunteers

Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia

NCT03863639
Conditions
Pre-Eclampsia, Neurocognitive Dysfunction
Interventions
Neuroimaging Procedures, Neuropsychological Assessment Procedures
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Mild Cognitive Impairment
Interventions
Medium Chain Triglyceride Oil, Placebo Oil
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
50 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baton Rouge, Louisiana