Independent directory Public ClinicalTrials.gov records United States
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Showing 961–984 of 1,074 matching trials from the live ClinicalTrials.gov search.
Conditions
Memory Performance, Hippocampal Activity
Interventions
TMS electrical stimulation parameters during cognitive and memory demands, DES electrical stimulation parameters during cognitive and memory demands
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Chicago, Illinois • St Louis, Missouri
Completed Not applicable Interventional Results available

Behavioral Weight Loss and Stigma Reduction

NCT03704064
Conditions
Obesity
Interventions
Stigma-Reduction Intervention, Behavioral Weight Loss (BWL)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Administration Method of Cognitive Screening in Older Individuals With Hearing Loss

NCT03402932
Conditions
Hearing Loss, Sensorineural, Cognitive Impairment
Interventions
Auditory amplified, Visual, Auditory unamplified
Other
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Evanston, Illinois
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

NCT02360371
Conditions
Opioid Sensitivity, Individual Difference, Abuse Opioids
Interventions
Within-subject test of blinded study medication
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Chronic Kidney Disease (CKD), Health Communication, Patient Comprehension
Interventions
Chronic Kidney Disease (CKD) Lab Result Communication Tool
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Completed No phase listed Observational Accepts healthy volunteers

Synaptic Injury and Functional Connectivity in Alzheimer's Disease

NCT03300726
Conditions
Alzheimer Disease, Late Onset
Interventions
CSF analysis, Functional MRI
Diagnostic Test · Radiation
Lead sponsor
Ohio State University
Other
Eligibility
60 Years to 95 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Mild Cognitive Impairment (MCI), Alzheimer Disease
Interventions
The Canary Application
Other
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
50 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Hackensack, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers

Social Cognition Assessment in Young Adults

NCT02922400
Conditions
Cognitive Function 1, Social
Interventions
Social Cognition Assessment and Training
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
17 Years to 40 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 4 Interventional Results available

The ISLAND Study: InSuLa Assessed Needs for Depression

NCT02137369
Conditions
Depression
Interventions
Selective serotonin re-uptake inhibitor, Cognitive Behavioral Therapy, Combination treatment (SSRI + CBT)
Drug · Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Chronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, Interstitial, Cystitis, Chronic Interstitial, Interstitial Cystitis, Interstitial Cystitis, Chronic, Interstitial Cystitis (Chronic) With Hematuria, Interstitial Cystitis (Chronic) Without Hematuria, Chronic Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions
Psychosocial Treatment, Pelvic Floor Physical Therapy
Behavioral · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Franklin, Tennessee
Conditions
Cognitive Performance, Attention, Reaction Time, Caffeine
Interventions
Caffeinated Coffee, Decaffeinated Coffee Placebo
Dietary Supplement
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Completed No phase listed Observational Accepts healthy volunteers Results available

Dual-Task Cost in Bilateral Hearing Loss

NCT05540535
Conditions
Bilateral Hearing Loss, Healthy Aging
Interventions
Gait assessment, Cognitive assessment
Other
Lead sponsor
New York University
Other
Eligibility
40 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
New York, New York
Conditions
Multiple Sclerosis, Cognitive Ability, General
Interventions
Ginkgo biloba, Placebo
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Portland, Oregon • Seattle, Washington
Conditions
Multiple Sclerosis, Cognition Disorders
Interventions
Memantine
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
4
States / cities
Los Angeles, California • Portland, Oregon • Dallas, Texas + 1 more
Conditions
Lymphoma Receiving CAR-T Therapy
Interventions
neurocognitive evaluations, brain MRIs, Blood samples
Behavioral · Diagnostic Test · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
HIV Infections, STI, HIV Pre-exposure Prophylaxis
Interventions
Combine mobile app, Motivational interview, HIV/STI testing
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
473 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Cognitive/Functional Effects, Depression, Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
modafinil, cognitive assessment, psychosocial assessment and care, quality-of-life assessment
Drug · Procedure
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Charlottesville, Virginia
Completed No phase listed Observational Results available

Cognition in Patients With Hypoglycemia, Without Diabetes

NCT04430582
Conditions
Hypoglycemia, Cognition
Interventions
Cognitive Assessment (not diagnostic), ECG
Other · Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
22 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Mild Cognitive Impairment (MCI), Opioid Use, Cognitive Dysfunction, Postoperative Pain
Interventions
Not listed
Lead sponsor
Miklos Kertai
Other
Eligibility
18 Years and older
Enrollment
552 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Type 2 Diabetes Mellitus
Interventions
ASMART, Control Group
Behavioral · Other
Lead sponsor
KRJG Services Inc.
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Warsaw, Indiana
Conditions
Fat Consumption, Inflammatory Markers
Interventions
Inflammatory markers test in blood prior to surgery, Inflammatory markers test in CSF (cerebrospinal fluid), MOCA test, CAM-3D
Diagnostic Test
Lead sponsor
Ohio State University
Other
Eligibility
60 Years and older
Enrollment
62 participants
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Face Masks During Exercise

NCT04833010
Conditions
Cardiopulmonary, Exercise, Cognitive Performance, Covid19
Interventions
Cardiopulmonary Exercise Test, Cognitive Performance Test
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Frisco, Texas
Conditions
Episodic Memory
Interventions
Cognitive testing
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Neuroimaging of Dystonia

NCT02046447
Conditions
Primary Cervical Dystonia, DYT 1 Dystonia
Interventions
Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control), DYT 1 Dystonia
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
7 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Gainesville, Florida