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ClinicalTrials.gov public records Last synced Sep 30, 2026, 1:26 PM EDT

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Showing 1–24 of 465 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive behavioral therapy (CBT) and medication Clear all
Completed Not applicable Interventional

Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder

NCT02750904
View directory record Official record
Conditions
Smoking, Bipolar Disorder
Interventions
Experimental plus Nicotine Replacement Therapy, Control plus Nicotine Replacement Therapy
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Palo Alto, California • Denver, Colorado • Bedford, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2019 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Brief Intervention for Drug Abusing Adolescents

NCT00350909
View directory record Official record
Conditions
Drug Abuse
Interventions
brief intervention (cognitive-behavioral therapy)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
13 Years to 19 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 20, 2008 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

Stepped Care for Treating Obsessive-Compulsive Disorder

NCT00316355
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Traditional CBT, Stepped-Care CBT
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 69 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Overlapping Neural Circuits in Pediatric OCD

NCT02421315
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
CBT treatment for OCD based on Exposure & Response Prevention (EX/RP) and when indicated medication treatment
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
5 Years to 17 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness

NCT04118283
View directory record Official record
Conditions
Chronic Pain, Schizophrenia, Psychotic Disorders, Bipolar Disorder, Affective Disorders, Psychotic
Interventions
Cognitive Behavioral Therapy for Chronic Pain, Health and Wellness
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Improving Antiretroviral Medication Adherence Among HIV-infected Youth

NCT01347437
View directory record Official record
Conditions
HIV Infection
Interventions
Positive STEPS
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
13 Years to 24 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Mindfulness Based Stress Reduction in Multiple Sclerosis (MS)

NCT01419301
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Mindfulness based stress reduction (MBSR)
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 70 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2014 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Phase 4 Interventional

Treatments for Anxiety: Meditation and Escitalopram

NCT03522844
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Agoraphobia
Interventions
Mindfulness-Based Stress Reduction, Escitalopram
Other · Drug
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 75 Years
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

Preventing Depressive Relapse in Pregnant Women With Recurrent Depression

NCT03623620
View directory record Official record
Conditions
Depression, Pregnancy Related, Antenatal Depression
Interventions
Digital Delivery of Mindfulness-Based Cognitive Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Boulder, Colorado • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Dysfunction

NCT03965897
View directory record Official record
Conditions
Pain, Function, Anxiety, Depression, Arthroplasty, Replacement, Knee, Veterans
Interventions
Acceptance and Commitment Therapy (ACT), Attention Control (AC)
Behavioral · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Examination of Sleep, Smoking Cessation, and Cardiovascular Health

NCT02941718
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sleep Advancement Counseling, General Health Information
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

Acceptance and Commitment Therapy for Chronic Pain in Cancer Survivors

NCT03661840
View directory record Official record
Conditions
Chronic Pain
Interventions
Acceptance and Commitment Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Sep 30, 2026, 1:26 PM EDT
Recruiting Phase 2 Interventional

Group Music Therapy for Chronic Pain Management in Active Duty Service Members

NCT07755540
View directory record Official record
Conditions
Chronic Pain
Interventions
Music intervention
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Phase 4 Interventional Results available

Prevention of Recurrence in Depression With Drugs and CT

NCT00057577
View directory record Official record
Conditions
Depression
Interventions
Cognitive Therapy, Medications
Behavioral · Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • Philadelphia, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validating the Use of a Subjectively Reported Sleep Vital Sign

NCT03018912
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder, Shift Work Sleep Disorders
Interventions
Sleep VS
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Selah Trial of Stress Interventions for Clergy: Mindfulness Based Stress Reduction, Daily Examen, and Stress Inoculation

NCT04625777
View directory record Official record
Conditions
Occupational Stress
Interventions
Mindfulness Based Stress Reduction, Daily Examen spiritual practice, Stress inoculation combination
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Sep 30, 2026, 1:26 PM EDT
Not yet recruiting Phase 4 Interventional

Modality Choice Before and After Failure for the Treatment of Painful Diabetic Neuropathy

NCT07795593
View directory record Official record
Conditions
Painful Diabetic Neuropathy (PDN), Diabetic Nephropathies
Interventions
Cognitive Behavioral Therapy (CBT), Oral Medication, Topical Medication
Device · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
23
States / cities
Stanford, California • Jacksonville, Florida • Chicago, Illinois + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Phase 1 Interventional

Cognitive-Behavioral Therapy for Pain and Opioid Dependence in Methadone Maintenance Treatment

NCT01334580
View directory record Official record
Conditions
Chronic Pain, Opiate Dependence
Interventions
Cognitive-Behavioral Therapy for Pain and Opioid Dependence, Methadone Drug Counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Phase 3 Interventional

Fatigue Intervention Trial for Breast Cancer Survivors

NCT00513136
View directory record Official record
Conditions
Fatigue
Interventions
Group based mind body medicine intervention, Group-based mind body medicine intervention + family focus
Behavioral
Lead sponsor
Mercy Medical Center
Other
Eligibility
Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

NCT04935606
View directory record Official record
Conditions
Drug Use
Interventions
Usual Care, QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks), QUIT-Mobile (QUIT Intervention plus weekly mobile-web app or text message weekly self-monitoring, automated feedback over 12 months)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
457 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Long Beach, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

NCT03904186
View directory record Official record
Conditions
Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking, Anxiety, Depression, Nicotine Dependence
Interventions
QUIT, Time-Matched Control (TM)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
3
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Active, not recruiting Not applicable Interventional

Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment

NCT05039554
View directory record Official record
Conditions
Opioid-use Disorder, Chronic Pain
Interventions
Acceptance and commitment therapy, Valera Smartphone Application, Treatment as Usual
Behavioral · Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional Results available

Improving Depression Management

NCT05050227
View directory record Official record
Conditions
Depression
Interventions
cCBT Enhanced Collaborative Care, Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2025 · Synced Sep 30, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Multiple Myeloma/Chronic Lymphocytic Leukemia Coach RCT

NCT05928156
View directory record Official record
Conditions
Multiple Myeloma, Chronic Lymphocytic Leukemia
Interventions
Myeloma Coach or CLL Coach Mobile App, Springboard Beyond Cancer informational website
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Sep 30, 2026, 1:26 PM EDT