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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:35 PM EDT

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Showing 289–312 of 479 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive performance Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Single Center, Randomized, Double-Blind,Crossover Study Comparing Effects Of Single-Dose Fexofenadine HCl 180 mg, Cetirizine 10 mg, and Placebo on Cognitive Performance in Naval Flight Personnel

NCT00637455
View directory record Official record
Conditions
Seasonal Allergic Rhinitis
Interventions
fexofenadine HCl
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 11, 2011 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurophysiological Targets for Cognitive Training in Schizophrenia

NCT00923078
View directory record Official record
Conditions
Schizophrenia
Interventions
Auditory Cognitive Training, Visual Cognitive Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Diet Composition on Performance, Expenditure, Blood Lipids, and Appetite Hormones in Highly Trained Cyclists

NCT04097171
View directory record Official record
Conditions
Endurance Cycling Performance
Interventions
Diet
Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 23, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

NEPAL (Neuromodulatory Examination of Pain and Mobility Across the Lifespan)

NCT02488863
View directory record Official record
Conditions
Musculoskeletal Pain, Pain, Chronic
Interventions
MRI Neuroimaging, Quantitative Sensory Testing, Questionnaires, Physical and Cognitive Function Testing
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
4
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Radical Openness for Adolescents Pilot

NCT05913557
View directory record Official record
Conditions
Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety
Interventions
Radically Open Dialectical Behavior Therapy (RO DBT)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 23, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cognitive Changes Associated With Breast Cancer Treatment

NCT00550134
View directory record Official record
Conditions
Breast Cancer, Cognitive Side Effects of Cancer Treatments, Stage I, II and III A Breast Cancer
Interventions
Questionnaires, MRI, Comet assay and Cell senescence
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2021 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology

NCT03674398
View directory record Official record
Conditions
Post-Concussion Syndrome, Post-Traumatic Headache, Post-Concussive Syndrome, Chronic, Head Injury, MTBI - Mild Traumatic Brain Injury, Acquired Brain Injury, Closed Head Injury
Interventions
Exercise+CT, Exercise only
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 23, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Dose-Response Impact of Glucosyl-Hesperidin (CitraPeak) on Exercise Performance, Blood Flow, Stress, Cognition, and Other Perceptual Indicators

NCT06672952
View directory record Official record
Conditions
Exercise Performance, Exercise Recovery, Cognitive Function, Nitric Oxide, Blood Flow, Endurance Exercise
Interventions
400 mg CITRAPEAK® (glucosyl-hesperidin) supplementation, Placebo, 200 mg CITRAPEAK® (glucosyl-hesperidin) supplementation
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 23, 2026, 1:35 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression

NCT05966532
View directory record Official record
Conditions
Major Depressive Disorder (MDD), Healthy Adult Volunteer
Interventions
Hot Cognitive Task, Cold cognitive tasks, Structural magnetic resonance imaging (sMRI), Magnetoencephalography imaging (MEG), four self-report forms per the requirement of the NIH Common Data Elements project, Four self-report measures to assess interpersonal functioning, Clinical assessments, ATHF
Behavioral · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
Arlington, Texas • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM

NCT05540652
View directory record Official record
Conditions
HIV, Minority Stress, Mental Health Wellness 1
Interventions
Mindfulness-Based Queer Resilience (MBQR)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of a Dietary Supplement on Cognitive Performance in Highly Trained Athletes.

NCT05926050
View directory record Official record
Conditions
Reaction Time
Interventions
Treatment (CopaPrime+ (USANA Health Sciences), Placebo
Dietary Supplement · Other
Lead sponsor
USANA Health Sciences
Industry
Eligibility
18 Years to 30 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Park City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 23, 2026, 1:35 PM EDT
Active, not recruiting Phase 2 Interventional

Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement

NCT06052176
View directory record Official record
Conditions
Cirrhosis, Hepatic Encephalopathy
Interventions
Albumin Infusion
Drug
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 23, 2026, 1:35 PM EDT
Recruiting Phase 2Phase 3 Interventional

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

NCT06273527
View directory record Official record
Conditions
Anxiety Disorders, Depression, Post Traumatic Stress Disorder
Interventions
COGENT, Sham Program
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 55 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reliability and Validity of Online Cognitive Assessments

NCT02382393
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Brain Performance Test (BPT, Lumos Labs, Inc), Computerized Assessment
Other
Lead sponsor
Lumos Labs, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
1,152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

NCT00438438
View directory record Official record
Conditions
Healthy
Interventions
forced desynchrony protocol with sleep restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2011 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Results available

Cognitive Rehabilitation in Post-COVID-19 Syndrome

NCT06136871
View directory record Official record
Conditions
Post-COVID-19 Syndrome
Interventions
CO-OP Procedures, Inactive Control Group
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 23, 2026, 1:35 PM EDT
Recruiting Not applicable Interventional

Assessing DCog Short for Neurotoxicity in CAR-T

NCT07403812
View directory record Official record
Conditions
Neurotoxicity, Neurotoxicity Syndromes, Hematologic Malignancy, Immune Effector Cell Associated Neurotoxicity Syndrome
Interventions
DCog Short
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Citicoline Dose on Energy Drink Efficacy

NCT06890962
View directory record Official record
Conditions
Cognitive Performance, Gaming Performance, Blood Pressure, Heart Rate, Mood
Interventions
Energy drink consumption
Dietary Supplement
Lead sponsor
Nathaniel Jenkins
Other
Eligibility
18 Years to 50 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Aerobic Exercise and Gaming on Cognitive Performance

NCT02437097
View directory record Official record
Conditions
Cognitive Performance in Healthy Volunteers
Interventions
Aerobic exercise, Video Gaming, Aerobic exercise and Video Gaming, Control
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2016 · Synced Oct 23, 2026, 1:35 PM EDT
Completed No phase listed Observational

Working Memory in Overweight Children With and Without Loss of Control Eating

NCT04117542
View directory record Official record
Conditions
Binge Eating, Pediatric Obesity
Interventions
Observational
Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
30 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Oct 23, 2026, 1:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cognitive Function and Cue-Reactivity Study

NCT00194246
View directory record Official record
Conditions
Cognitive Performance, Food Cravings
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Oct 23, 2026, 1:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Alpha Hope Dietary Supplement on Health and Cognitive Performance

NCT05589051
View directory record Official record
Conditions
Cognitive Change
Interventions
Drink
Dietary Supplement
Lead sponsor
University of Memphis
Other
Eligibility
40 Years to 70 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 23, 2026, 1:35 PM EDT
Enrolling by invitation Not applicable Interventional

To Drill or Not to Drill: Do Memory Drills Help Train the Ability to "Remember to Remember" in Veterans

NCT06656637
View directory record Official record
Conditions
Memory Deficit
Interventions
Memory Drilling, Compensatory Strategies, Cognitive Processing Therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 23, 2026, 1:35 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Environmental Temperatures in Respiratory Control

NCT07470086
View directory record Official record
Conditions
Work of Breathing
Interventions
Thermoneutral temperature environment, Cold temperature environment, Hot temperature environment
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2029
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 23, 2026, 1:35 PM EDT