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ClinicalTrials.gov public records Last synced Oct 23, 2026, 2:13 AM EDT

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Showing 121–144 of 479 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive performance Clear all
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Night Call on Intellectual Performance

NCT02697266
View directory record Official record
Conditions
Sleep Deprivation
Interventions
No intervention
Other
Lead sponsor
Haleh Saadat
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2016 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia

NCT02379156
View directory record Official record
Conditions
Tetraplegia, Hypothermia, Mild Cognitive Impairment
Interventions
Midodrine Hydrochloride, Cool Temperature
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 68 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Huperzine A on Cognitive Function and Perception of Effort During Exercise

NCT03445104
View directory record Official record
Conditions
Cognitive Enhancement During Exercise
Interventions
Huperzine A, Placebo
Other
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Oct 23, 2026, 2:13 AM EDT
Not yet recruiting Not applicable Interventional

Speed of Processing Training to Improve Cognitive Functioning and Driving Performance in Head and Neck Cancer Survivors

NCT07740616
View directory record Official record
Conditions
Head and Neck Cancer (H&N)
Interventions
Speed of Processing Training, Home-Based Sham Training
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game

NCT05506852
View directory record Official record
Conditions
Healthy Aging
Interventions
Web-based training strategy, Web-based regular training (no strategy)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
60 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluate the Effects of Citicoline on Mood in Healthy Adults

NCT07089238
View directory record Official record
Conditions
Healthy
Interventions
Citicoline, Placebo
Dietary Supplement
Lead sponsor
Kirin Holdings Company, Limited
Industry
Eligibility
21 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of Two Supplements on Cognitive Function, Cognitive Performance, and Mood

NCT07766564
View directory record Official record
Conditions
Cognitive Function, Cognitive Performance, Mood
Interventions
BrainJuice Supplement
Dietary Supplement
Lead sponsor
BrainJuice
Industry
Eligibility
18 Years to 57 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional

Assessing the Impact of Weighted Blankets on Anxiety Among Inpatients With Anorexia Nervosa: a Study Protocol

NCT04191720
View directory record Official record
Conditions
Anorexia Nervosa, Avoidant/Restrictive Food Intake Disorder, Anxiety
Interventions
Weighted blanket
Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Slow-wave Enhancement in Adults Aged 30-49

NCT04611828
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
30 Years to 49 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Phase 4 Interventional

The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury

NCT01339806
View directory record Official record
Conditions
Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With No Loss of Consciousness
Interventions
Cognitive Rehab, Brainworks, Informational Handout/Provider Visits
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Non-Invasive Brain Stimulation on Soldiers' Cognitive and Functional Performance

NCT04155333
View directory record Official record
Conditions
Performance Enhancement
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
United States Army Aeromedical Research Laboratory
Federal
Eligibility
18 Years to 40 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Rucker, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acquiring and Targeting Heat Exposures Necessary for Action

NCT05678738
View directory record Official record
Conditions
Heat Intolerance, Heat Stress, Fatigue; Heat
Interventions
Antioxidant Berry Supplementation, Acute and Chronic Exercise-Heat Stress, Placebo (non-juice) Supplementation
Dietary Supplement · Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Memory and Cognitive Performance Study

NCT04025255
View directory record Official record
Conditions
Cognitive Function, Memory, Brain Health
Interventions
Braini, Placebo
Dietary Supplement
Lead sponsor
Vita Naturel, LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Asheville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness in the OR

NCT04515667
View directory record Official record
Conditions
Performance at Work
Interventions
Mindfulness, Video
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 29, 2025 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults

NCT06995560
View directory record Official record
Conditions
Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition, Psychomotor Performance, Neurophysiology
Interventions
Active Transcranial Electrical Stimulation, Sham Transcranial Electrical Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Field Implementation of iDETECT

NCT02529618
View directory record Official record
Conditions
Concussion, Brain Trauma
Interventions
integrated Display Enhanced Testing for Cognitive Impairment and mild traumatic brain injury (iDETECT), Riddell High Impact Technology (HIT) System, i1 Biometrics Vector Mouth Guard
Device
Lead sponsor
Emory University
Other
Eligibility
14 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Atlanta, Georgia • College Park, Georgia • Marietta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2016 · Synced Oct 23, 2026, 2:13 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Walking Sensation Study

NCT06975423
View directory record Official record
Conditions
Aging, Sensory Deficit
Interventions
Active lower-limb neuroprosthesis, Inactive lower-limb neuroprosthesis
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fermented Papaya and Driving Simulator Older Adult Study

NCT06672874
View directory record Official record
Conditions
Healthy
Interventions
Fermented Papaya Preparation (FPP)
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
70 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Potentials of Biodynamic Lighting for Home Office Workers

NCT05481424
View directory record Official record
Conditions
Cognitive Performance, Sleep, Alertness
Interventions
Biodynamic, Active Placebo
Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 23, 2026, 2:13 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

How Can We Help? Wellbeing Interventions for Choral Music Ensembles

NCT07298031
View directory record Official record
Conditions
Anxiety, Well-Being (Psychological Flourishing), Performance Anxiety
Interventions
Box breathing, Magnify, Emotion regulation through choral literature
Behavioral
Lead sponsor
Jess Walls
Other
Eligibility
10 Years to 20 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS)

NCT05683431
View directory record Official record
Conditions
Bipolar Disorder, Bipolar I Disorder, Bipolar Affective Disorder, Bipolar Disorder I, Bipolar Depression
Interventions
Cognitive Control of Emotion (CCE) Training
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 30 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 13, 2023 · Synced Oct 23, 2026, 2:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Determining the Impact of Emotive Intelligent Spaces

NCT04836286
View directory record Official record
Conditions
Color Perception
Interventions
Emotive Intelligent Spaces (EIS)
Behavioral
Lead sponsor
University of Idaho
Other
Eligibility
3 Years to 6 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Moscow, Idaho
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Oct 23, 2026, 2:13 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Human Behaviors Related to the Expectation of Pain

NCT03739645
View directory record Official record
Conditions
Fear Pain
Interventions
Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
16 Years to 88 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 23, 2026, 2:13 AM EDT