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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:02 PM EDT

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Showing 97–120 of 340 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive-Behavioral Treatment for Insomnia Clear all
Not yet recruiting Not applicable Interventional

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

NCT07397182
View directory record Official record
Conditions
Insomnia, Mild Cognitive Impairment
Interventions
Cognitive BehavioralTherapy for Insomnia (CBT-I), SleepSMART
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinician Training Program to Integrate Digital CBTI Into Routine Psychotherapy

NCT05814783
View directory record Official record
Conditions
Insomnia
Interventions
supported digital CBTI, digital CBTI
Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Researching Effective Sleep Treatments (Project REST)

NCT02120989
View directory record Official record
Conditions
Insomnia
Interventions
Partner-Assisted Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Phase 2Phase 3 Interventional

Group Cognitive Behavioral Therapy (CBT I) Vs. Quetiapine for Residual Insomnia Impairing Recovery Among Elderly With Stable Major Affective Disorders

NCT00462618
View directory record Official record
Conditions
Insomnia
Interventions
Quetiapine, Cogntive behavioral therapy
Drug · Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
60 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

Sequenced Therapies for Comorbid and Primary Insomnias

NCT01651442
View directory record Official record
Conditions
Insomnia Comorbid to Psychiatric Disorder, Primary Insomnia
Interventions
Behavioral Insomnia Therapy, Zolpidem, Trazodone, Cognitive Therapy
Behavioral · Drug
Lead sponsor
Jack Edinger, PhD
Other
Eligibility
21 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

Study of Trazodone & Cognitive Behavioral Therapy to Treat Insomnia

NCT01348542
View directory record Official record
Conditions
Insomnia
Interventions
Trazodone, Cognitive Behavioral Therapy
Drug · Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
30 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 6, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional

CF Wellness Program

NCT07071324
View directory record Official record
Conditions
Cystic Fibrosis (CF), Fatigue, Sleep Quality, Insomnia
Interventions
CF Wellness Program
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Denver, Colorado • Baltimore, Maryland • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Device Feasibility and Acceptability to Improve Insomnia in Cancer

NCT05875129
View directory record Official record
Conditions
Cancer, Insomnia Chronic
Interventions
VAVA prototype
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 39 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

P20 Extending Sleep to Reverse Metabolic Syndrome

NCT03596983
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Sleep Intervention, Week 2 Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Examination of Sleep, Smoking Cessation, and Cardiovascular Health

NCT02941718
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Sleep Advancement Counseling, General Health Information
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

Sleep Quality and Mechanisms of Cardiovascular Risks in Adults With Hypertension

NCT04009447
View directory record Official record
Conditions
Hypertension, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
30 Years to 60 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 6, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional

Sleep Mechanisms Of Regulating Emotions

NCT06373718
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

NCT03954210
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD

NCT03937713
View directory record Official record
Conditions
Complex Insomnia
Interventions
eszopiclone, Brief behavioral therapy for insomnia
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

The Association Between CBT-I Dose and Innate Immunity in Insomnia and Fatigue in Prostate Cancer Patients

NCT06604247
View directory record Official record
Conditions
Breast Cancer, Prostate Cancer
Interventions
Cognitive Behavioral therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
40 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults

NCT01142349
View directory record Official record
Conditions
Pain Dysfunction, Sleep Disturbance, Osteoarthritis
Interventions
Lifestyles A, Lifestyles B, Lifestyles C
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
60 Years and older
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 19, 2013 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

Optimizing Efficiency and Impact of Digital Health Interventions for Caregivers

NCT04986904
View directory record Official record
Conditions
Family Caregivers, Insomnia, Sleep Initiation and Maintenance Disorders
Interventions
SHUTi (Sleep Healthy Using the Internet)
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis

NCT01683799
View directory record Official record
Conditions
Osteoarthritis of the Knee, Insomnia, Knee Pain
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
50 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 6, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

NCT05516277
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
Interventions
Behavioral Sleep Education Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress

NCT01743339
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depression, Sleep
Interventions
Cognitive Behavioral Therapy, Control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

Triple Vulnerability? Circadian Tendency, Sleep Deprivation and Adolescence

NCT01828320
View directory record Official record
Conditions
Eveningness/Sleep
Interventions
Cognitive Behavior Therapy for Insomnia, Interpersonal and Social Rhythms Therapy, Chronotherapy, Psychoeducation
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
10 Years to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Mobile Intervention to Improve Functional Health and Community Engagement of Post-9/11 Veterans With Chronic Insomnia

NCT03305354
View directory record Official record
Conditions
Chronic Insomnia
Interventions
CBTI app intervention, Physical Activity intervention
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
21 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 6, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Sleep To Reduce Incident Depression Effectively

NCT03322774
View directory record Official record
Conditions
Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions
digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
1,237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 6, 2026, 10:02 PM EDT
Recruiting Not applicable Interventional

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

NCT07385105
View directory record Official record
Conditions
Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions
Cognitive behavioral Therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 6, 2026, 10:02 PM EDT