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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:40 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1177–1200 of 2,772 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cognitive-behavioral therapy (CBT) Clear all
Active, not recruiting Phase 4 Interventional

Ketamine-Assisted Mindfulness-Based Cognitive Therapy for Depression: A Pilot Study

NCT05950711
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Combination use of MBCT and IV Ketamine
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 17, 2026, 11:40 AM EDT
Not yet recruiting Phase 1 Interventional

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Mobile Sleep Intervention for OEF, OIF and OND Veterans

NCT02392000
View directory record Official record
Conditions
Chronic Insomnia
Interventions
WatchPAT sleep monitor, CBT-i Coach mobile app
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2018 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

NCT06172907
View directory record Official record
Conditions
Cancer, Survivorship, Caregiver Burden, Psychological Distress, Coping Skills, Couples
Interventions
Young Adults Coping with Cancer Together Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Boston, Massachusetts • Concord, Massachusetts • Danvers, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Recruiting Not applicable Interventional

Neural Connectivity During Therapy for Adolescent PTSD

NCT05423444
View directory record Official record
Conditions
PTSD, Adolescent, Psychological Trauma
Interventions
TF-CBT, TAU
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
12 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Terminated Phase 4 Interventional Results available

CBT as an Adjunct to SRIs in the Treatment of BDD

NCT00211809
View directory record Official record
Conditions
Body Dysmorphic Disorder
Interventions
Cognitive Behavioral Therapy, Venlafaxine
Behavioral · Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
16 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2017 · Synced Oct 17, 2026, 11:40 AM EDT
Terminated Phase 1 Interventional

Novel Treatments to Enhance Smoking Cessation Before Cancer Surgery: Effects on Smoking and Surgical Outcomes

NCT01479998
View directory record Official record
Conditions
Smoking Cessation
Interventions
standard care, standard care plus contingency management
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

The Association Between Loneliness and Substance Use

NCT04938492
View directory record Official record
Conditions
Opioid Use, Loneliness
Interventions
Cognitive Behavioral Therapy for loneliness (CBT-L), Physical Health Education Training (PHET)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional

Cognitive Processing Therapy Versus Its Individual Components in the Treatment of Post-Traumatic Stress Disorder and Depression in Women Who Have Been Sexually Abused

NCT00245232
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Cognitive Therapy, Cognitive Processing Therapy, Written Exposure
Behavioral
Lead sponsor
University of Missouri, St. Louis
Other
Eligibility
18 Years and older · Female only
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Oct 17, 2026, 11:40 AM EDT
Active, not recruiting Not applicable Interventional

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT04953806
View directory record Official record
Conditions
COPD, Depression, Anxiety
Interventions
Step-CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional

Preventing Premature Death in Patients With Serious Opioid-related Infection

NCT03999450
View directory record Official record
Conditions
Opioid Use
Interventions
brief motivational intervention (BMI), cognitive behavioral therapy
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Group-based Mindfulness for Chronic Pain in the Primary Care Setting

NCT04129450
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
Group medical visits with mindfulness-based stress reduction, Usual PCP care
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional

SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence

NCT04080180
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Contingency Management, Brief Motivational Interviewing + Substance Free Activities + Mindfulness
Behavioral
Lead sponsor
Karen Derefinko, PhD
Other
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Group Based Exposure Therapy for Combat-Related PTSD

NCT00535223
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Based Exposure Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Male only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MI-CBT Adherence Program for Lifestyle Interventions in Older Adults

NCT04817176
View directory record Official record
Conditions
Mild Cognitive Impairment, Adherence, Patient, Ketosis
Interventions
Motivational Interviewing-Cognitive Behavioral Therapy Ketogenic Nutrition Adherence Program, Ketogenic Nutrition Program
Behavioral · Other
Lead sponsor
Florida State University
Other
Eligibility
60 Years to 85 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CBT-based Internet Intervention for Adults With Tinnitus in the United States

NCT04004260
View directory record Official record
Conditions
Tinnitus
Interventions
Internet-based Cognitive Behavior Therapy
Behavioral
Lead sponsor
Lamar University
Other
Eligibility
18 Years and older
Enrollment
315 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Beaumont, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Facing Your Fears in Schools: Implementing a CBT Program for Students With ASD or Other Special Learning Needs

NCT03685474
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Facing Your Fears - School Based, Usual Care
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 14 Years
Enrollment
389 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Oct 17, 2026, 11:40 AM EDT
Terminated Not applicable Interventional

BNT001 Digital Therapeutic Feasibility Pilot Study

NCT04857008
View directory record Official record
Conditions
Cancer
Interventions
BNT001
Device
Lead sponsor
Blue Note Therapeutics
Industry
Eligibility
17 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional

Exploring the Outcomes and Financial Impact of a CBT-I Group Program Provided by Registered Nurses for Adults With Insomnia

NCT02038556
View directory record Official record
Conditions
Insomnia
Interventions
cognitive behaviorial therapy -Insomnia
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 8, 2015 · Synced Oct 17, 2026, 11:40 AM EDT
Recruiting Not applicable Interventional

Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily

NCT07425119
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Cognitive Behavioral Therapy (CBT), Cue-based treatment intervention
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Phase 4 Interventional Results available

Combination Nicotine Replacement for Alcoholic Smokers

NCT00064844
View directory record Official record
Conditions
Smoking, Alcoholism
Interventions
Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Newington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2021 · Synced Oct 17, 2026, 11:40 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

NCT05624931
View directory record Official record
Conditions
Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
Interventions
Brief CBT-Based Intervention, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
15 Years and older · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 17, 2026, 11:40 AM EDT
Completed Not applicable Interventional

A Single Session Pain Psychology Class for Spine Surgery Patients

NCT03985436
View directory record Official record
Conditions
Lumbar; Injury
Interventions
Trek for Surgical Success
Behavioral
Lead sponsor
Sara Davin, PsyD, MPH
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 17, 2026, 11:40 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings

NCT07755137
View directory record Official record
Conditions
Autism Spectrum Disorder, Depressive Disorder, Anxiety Disorders
Interventions
CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU)
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
11 Years to 17 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 17, 2026, 11:40 AM EDT