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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:11 PM EDT

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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Cold Stimulation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Relationship Between Chiropractic Care and Autonomic Nervous System Regulation

NCT05401903
View directory record Official record
Conditions
Chiropractic Maintenance Care and Heart Rate Variability
Interventions
Chiropractic Maintenance Care
Other
Lead sponsor
Northeast College of Health Sciences
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seneca Falls, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 2:11 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain

NCT00678717
View directory record Official record
Conditions
Chronic Pain
Interventions
Autonomic Evaluation
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 16, 2018 · Synced Oct 21, 2026, 2:11 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Exploring Pain Modulation With TMS and Repeated Pain Conditioning in Healthy Individuals

NCT06726018
View directory record Official record
Conditions
Healthy Adult
Interventions
Conditioned Pain Modulation (CPM)
Behavioral
Lead sponsor
Priyanka Rana, PT, MPT, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stimulation of Diet-Induced Thermogenesis by Cold-Exposure

NCT01898949
View directory record Official record
Conditions
Thermogenesis, Brown Adipose Tissue
Interventions
Cold Exposure
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Phase 4 Interventional

Ziconotide as First-Line IDT

NCT03321955
View directory record Official record
Conditions
Neuropathic Pain
Interventions
Ziconotide 100 MCG(microgram)/ML Intrathecal Solution, Quantitative sensory testing, Serum markers: Interleukin-1, Interleukin-6, and tumor necrosis factor
Drug · Diagnostic Test
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 21, 2026, 2:11 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neuromodulation Treatment of Vestibular Migraines

NCT02866084
View directory record Official record
Conditions
Headache
Interventions
Device
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain

NCT04494698
View directory record Official record
Conditions
Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
Interventions
Duotherm VibraCool Back Device, TENS 8-channel unit
Device
Lead sponsor
MMJ Labs LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Landover, Maryland • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Noxipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation for Chronic Pain

NCT01578148
View directory record Official record
Conditions
Shoulder Pain, Neck Pain
Interventions
Noxipoint Therapy, Physical Therapy
Procedure
Lead sponsor
Pain Cure Center, California
Industry
Eligibility
18 Years to 64 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 21, 2026, 2:11 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

NCT06456411
View directory record Official record
Conditions
Breast Carcinoma, Kidney Carcinoma, Carcinoma
Interventions
Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention, Cold Stimulation
Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Phase 2 Interventional Results available

Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia

NCT01085903
View directory record Official record
Conditions
Spatial Neglect, Dysphagia
Interventions
Modafinil, Placebo, Baseline, CPS, Post CPS, Follow up
Drug · Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
19 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Conway, Arkansas • Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Vestibular Innovation in Pain

NCT06559839
View directory record Official record
Conditions
Pain, Fatigue, Quality of Life
Interventions
Vestibulocortical Stimulation
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 99 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Dual Stimulation for Spinal Cord Injury

NCT07467850
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
tsDCS+pDCS, Low-level laser therapy
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ABVN Phase 1 - Vagal Maneuvers

NCT07881276
View directory record Official record
Conditions
Healthy Subjects
Interventions
Vagal Maneuvers, Multi-Electrode Array (MEA) Recording
Other · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management

NCT07160049
View directory record Official record
Conditions
Pain Management, Peripheral Neuropathic Pain
Interventions
Cold Pressor Task - Upper Limb, Algometry Pain Tests in the Upper Limb, Algometry Pain Tests in the Lower Limb
Device
Lead sponsor
Evan (Huiliang) Wang
Other
Eligibility
20 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional

ABVN Phase 2 - Vagal Maneuvers

NCT07881289
View directory record Official record
Conditions
Gastroparesis
Interventions
Vagal Maneuvers
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Active, not recruiting Not applicable Interventional

Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury

NCT05960448
View directory record Official record
Conditions
Orthostatic Hypotension
Interventions
Transcutaneous Spinal Cord Stimulation (TSCS), Sham Transcutaneous Spinal Cord Stimulation
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional

Vestibular Innovation in Pain 2

NCT07423377
View directory record Official record
Conditions
Fibromyalgia, Nociplastic Pain
Interventions
Vestibulocortical Stimulation
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

NCT03258580
View directory record Official record
Conditions
Normal Physiology, Healthy Volunteers, Pain
Interventions
Medoc thermal stimulator, Electric shock stimulator, Cold water bath, Pain assessment performance feedback
Device · Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 60 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development

NCT01422395
View directory record Official record
Conditions
Fertility
Interventions
Freezing
Procedure
Lead sponsor
Main Line Fertility Center
Other
Eligibility
21 Years to 37 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

NCT01996449
View directory record Official record
Conditions
Hypertension
Interventions
Eplerenone, Amlodipine, Microneurography, Rhythmic handgrip exercise, Sustained hand grip, Forearm blood flow, Arm cycling exercise, Cold Pressor test
Drug · Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2022 · Synced Oct 21, 2026, 2:11 PM EDT
Completed Not applicable Interventional

Vestibular Caloric Stimulation and the Modulation of Pain in Fibromyalgia

NCT05004194
View directory record Official record
Conditions
Fibromyalgia
Interventions
Vestibular Caloric Stimulation
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Oct 21, 2026, 2:11 PM EDT
Recruiting Phase 2 Interventional

Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin Lymphoma

NCT04871607
View directory record Official record
Conditions
Recurrent Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
Interventions
Basiliximab, Carmustine, Cytarabine, Etoposide, Genetically Engineered Hematopoietic Stem Progenitor Cells, Recombinant Granulocyte Colony-Stimulating Factor, Yttrium Y 90 Basiliximab
Biological · Drug
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 21, 2026, 2:11 PM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

ASIS for Enbrel in Plaque Psoriasis

NCT02112097
View directory record Official record
Conditions
Plaque Psoriasis.
Interventions
Gadolinium, Efficacy of Enbrel subcutaneously at Week 12, Efficacy of Enbrel subcutaneously at Week 24, Efficacy of Enbrel subcutaneously at Week 36, Efficacy of Enbrel subdermally at Week 12, Efficacy of Enbrel subdermally at Week 24, Efficacy of Enbrel subdermally at Week 36, PASI 75 n(%) subcutaneously at Week 12, PASI 75 n(%) subcutaneously at Week 24, PASI 75 n(%) subcutaneously at Week 36, PASI 75 n(%) subdermally at Week 12, PASI 75 n(%) subdermally at Week 24, PASI 75 n(%) subdermally at Week 36, Adverse Reactions of Enbrel subcutaneously, Adverse Reactions of Enbrel subdermally at Week 36
Drug
Lead sponsor
ASIS Corporation
Industry
Eligibility
21 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Westminster, California
Source: ClinicalTrials.gov public record
Updated Jun 24, 2015 · Synced Oct 21, 2026, 2:11 PM EDT
Recruiting Not applicable Interventional

Olfactory Biopsies

NCT07021040
View directory record Official record
Conditions
Alzheimer Disease, Smell Loss, Smell Dysfunction
Interventions
olfactory testing, Odor stimulation, Olfactory biopsy
Diagnostic Test · Other · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 21, 2026, 2:11 PM EDT