Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 6, 2026, 4:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Type II Diabetes, Periodontal Disease
Interventions
Triclosan containing toothpaste, Non-triclosan containing toothpaste
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Dentin Sensitivity
Interventions
Mouthwash, Potassium nitrate toothpaste, Sodium fluoride toothpaste
Device · Drug
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years and older
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Evaluate Dental Plaque Benefit of a Preventive Treatment Gel

NCT03546491
Conditions
Dental Plaque
Interventions
Preventive Gel, Marketed Control
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Mason, Ohio
Terminated Not applicable Interventional Results available

Sodium Fluoride PET/CT for the Evaluation of Skeletal Cancer

NCT01541358
Conditions
Bone Cancer
Interventions
fluorine F 18 sodium fluoride, positron emission tomography/computed tomography
Radiation · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Stanford, California
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste

NCT01072188
Conditions
Hypersensitivity
Interventions
Arginine/Calcium Carbonate, Nupro - Fluoride Free
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Langhorne, Pennsylvania
Completed Phase 4 Interventional Accepts healthy volunteers

A Study of Virtually Supervised Mouthwash and Interdental Brushes

NCT05756673
Conditions
Healthy
Interventions
Colgate Cavity Protection Toothpaste, LISTERINE ZERO Alcohol Mouthwash COOL MINT, LISTERINE COOL MINT Antiseptic Mouthwash, TePe Original Interdental Brush
Drug · Device
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years and older
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fort Wayne, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ

NCT02195583
Conditions
Oral Hygiene
Interventions
Sodium fluoride (1426 ppm), Sodium fluoride (1150 ppm), Sodium fluoride (250 ppm), Sodium fluoride (1426 ppm) + zinc base A, Sodium fluoride (1426 ppm) + zinc base B, Fluoride (0 ppm)
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Phase 2 Interventional Results available

F-18 Sodium Fluoride in Prostate Cancer

NCT01240551
Conditions
Prostate Neoplasm
Interventions
F-18 NaF
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Dental Caries
Interventions
Test Dentifrice, Reference Dentifrice, Negative Control Dentifrice
Drug
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 85 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Gingivitis
Interventions
Stannous fluoride, Sodium monofluorophosphate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Fort Wayne, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fluoride Varnish for Treatment of White Spot Lesions

NCT01500187
Conditions
White Spot Lesions
Interventions
Vanish Varnish, Pediagel
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
12 Years to 16 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Prostatic Neoplasms, Prostate Cancer
Interventions
TAK-700, Fluorine F 18 Sodium Fluoride, Positron Emission Tomography, Computed Tomography
Drug · Radiation · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
ASD I, ASD2
Interventions
Hum by Colgate Smart Kids Toothbrush (battery powered) - 490000006871
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
5 Years to 12 Years
Enrollment
17 participants
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Silver Diamine Fluoride Pilot Study (SDF)

NCT02591147
Conditions
Dental Caries
Interventions
Silver Diamine Fluoride 38%, Group 2 (Placebo)
Device
Lead sponsor
Justine Kolker
Other
Eligibility
21 Years to 64 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Phase 4 Interventional Accepts healthy volunteers

A Twelve Week Study of Prototypes Mouth Rinses

NCT05526586
Conditions
Healthy
Interventions
Colgate Cavity Protection Toothpaste, Zero Alcohol Gum Prototype, Alcohol Gum Prototype, Listerine Cool Mint Antiseptic Mouthwash, 5% Hydroalcohol
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Fort Wayne, Indiana
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion

NCT01128972
Conditions
Tooth Erosion
Interventions
Sodium fluoride, Sodium monoflurophosphate, Sterile water
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Phase 3 Interventional Results available

Effect of Evolocumab on Coronary Atherosclerosis

NCT03689946
Conditions
Cardiovascular Disease, Hyperlipidemia
Interventions
Evolocumab, 18F-NaF PET, CCTA, Omnipaque, Metoprolol, Nitroglycerin
Drug · Diagnostic Test
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Dentinal Hypersensitivity
Interventions
Sensi-IP toothpaste, Sodium Fluoride Toothpaste
Device
Lead sponsor
IR Scientific Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dental Office Prevention Strategies for Children

NCT02004990
Conditions
Dental Plaque
Interventions
Single cleansing procedure of 10% Povidone Iodine
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
6 Years to 13 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Bone Metastases
Interventions
Bone Scan: F18-Fluoride PET/CT or TC-MDP
Device
Lead sponsor
American College of Radiology - Image Metrix
Industry
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
15
States / cities
Scottsdale, Arizona • Freemont, California • Los Angeles, California + 9 more
Recruiting Phase 2 Interventional Accepts healthy volunteers

Ultralow Dose PET Imaging for 18F-NaF Uptake

NCT07284563
Conditions
Healthy Volunteer, Bone Alteration, Bone and Joint Cancer, Bone and Joint Infection, Arthritis
Interventions
18F-NaF
Drug
Lead sponsor
Akiva Mintz
Other
Eligibility
18 Years to 120 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Englewood, New Jersey
Conditions
Prostate Cancer
Interventions
Sodium Fluoride (NaF) Positron Emission Tomography/Computed Tomography (PET/CT) imaging
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Male only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
3
States / cities
Bethesda, Maryland • New York, New York • Madison, Wisconsin
Conditions
Dental Plaque
Interventions
Livionex® Dental Gel, PreviDent 5000 plus/Tom's of Maine Children's toothpaste, Kolibree Toothbrush
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Francisco, California
Conditions
Hormone-Resistant Prostate Cancer, Metastatic Malignant Neoplasm in the Bone, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
Interventions
Fluorine F 18 Sodium Fluoride
Radiation
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older · Male only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
4
States / cities
Boston, Massachusetts • Durham, North Carolina • Portland, Oregon + 1 more