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ClinicalTrials.gov public records Last synced Sep 22, 2026, 7:32 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Collagen dressing Clear all
Not yet recruiting Phase 2 Interventional

Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds

NCT07318792
View directory record Official record
Conditions
Wound Chronic Draining, Wound Closure
Interventions
Platelet-rich fibrin (PRF)
Device
Lead sponsor
Estar Medical dba Medical Technologies, LTD
Industry
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
3
States / cities
Bradenton, Florida • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional

SDRM® vs. Collagen for Diabetic Foot Ulcers

NCT05883098
View directory record Official record
Conditions
Diabetic Foot, Ulcer Foot, Wound Heal
Interventions
Wound debridement, Wound closure matrix application
Procedure · Device
Lead sponsor
Polymedics Innovations Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Circleville, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2023 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional Results available

Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of Care

NCT01716169
View directory record Official record
Conditions
Epidermolysis Bullosa Dystrophica, Epidermolysis Bullosa
Interventions
Helicoll, Standard of Care Dressings
Device
Lead sponsor
Stanford University
Other
Eligibility
7 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 4, 2016 · Synced Sep 22, 2026, 7:32 PM EDT
Terminated Not applicable Interventional Results available

Porcine Xenograft Versus Second Intention Healing

NCT03931746
View directory record Official record
Conditions
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Interventions
Porcine xenograft
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Bay Shore, New York • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2023 · Synced Sep 22, 2026, 7:32 PM EDT
Not listed Not applicable Interventional

Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails

NCT00641433
View directory record Official record
Conditions
Ingrown Nail
Interventions
oxidized regenerated cellulose collagen-silver, topical silver sulfadiazine cream
Device · Drug
Lead sponsor
Rosalind Franklin University of Medicine and Science
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
North Chicago, Illinois • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 23, 2008 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HRIPT for Collagen Dressing

NCT06283173
View directory record Official record
Conditions
Skin Sensitisation
Interventions
ColActive Plus Collagen Matrix Dressing
Device
Lead sponsor
Covalon Technologies Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SkinTE™ in the Treatment of Diabetic Foot Wounds

NCT03881254
View directory record Official record
Conditions
Diabetic Foot, Diabetic Foot Ulcer, Ulcer Foot
Interventions
Human Autologous Homologous Skin Construct, Additional Outer Dressing Applicaiton, Offloading, Fibracol Wound Dressing
Other
Lead sponsor
PolarityTE
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Martinsville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Sep 22, 2026, 7:32 PM EDT
Terminated Not applicable Interventional Results available

Medihoney and Santyl for Burn Injuries

NCT02250183
View directory record Official record
Conditions
Burns
Interventions
MEDIHONEY® GEL WITH ACTIVE LEPTOSPERMUM HONEY, Santyl
Device
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SkinTE® in the Treatment of Venous Leg Wounds

NCT03881267
View directory record Official record
Conditions
Venous Leg Ulcer, Venous Stasis, Venous Stasis Ulcer
Interventions
Human Autologous Homologous Skin Construct, Additional Outer Dressing Application, Fibracol Wound Dressing
Other
Lead sponsor
PolarityTE
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Martinsville, Virginia • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2022 · Synced Sep 22, 2026, 7:32 PM EDT
Terminated Not applicable Interventional Results available

An Evaluation of a Collagen Dressing to Treat Chronic, Stalled Lower-extremity Wounds

NCT03723603
View directory record Official record
Conditions
Wound
Interventions
Fibrillar collagen powder dressing
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 22, 2026, 7:32 PM EDT
Recruiting Not applicable Interventional

Clinical Trial Evaluating an Amnion Membrane Allograft Intended for Use in the Management of Non- Healing Venous Leg Ulcers Versus Standard Of Care Alone

NCT06764953
View directory record Official record
Conditions
Venous Leg Ulcers
Interventions
E-GRAFT ™, FIBRACOL™
Other · Device
Lead sponsor
Skye Biologics Holdings, LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 22, 2026, 7:32 PM EDT
Not listed Not applicable Interventional

A Comparison of Two Socket Sealing Collagen Matrices for Extraction Socket Management

NCT03003819
View directory record Official record
Conditions
Tooth Loss
Interventions
Control Collagen Wound Dressing, Test Collagen Matrix
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Fenton, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional

Characterizing the Effects of Platelet-Rich Fibrin (PRF) as a Palatal Wound Dressing on Quality of Life and Sleep Following Mucogingival Surgery. Study Was Conducted at the Air Force Post Graduate Dental School. All HIPPA Consents and Research Informed Consents Are Located at JBSA-Lackland.

NCT07637838
View directory record Official record
Conditions
Palatal Donor Site Wound Healing, Platelet Rich Fibrin, Sleep Quality, Pain, Analgesic Consumption
Interventions
Platelet rich fibrin, Control Group: collagen matrices or oxidized cellulose membrane
Procedure · Other
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 99 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 22, 2026, 7:32 PM EDT
Recruiting Not applicable Interventional

Clinical Trial Evaluating an Amnion Membrane Allograft for Use in the Management of Non- Healing Diabetic Foot Ulcers Versus Standard Of Care

NCT06767501
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs)
Interventions
E-GRAFT ™, FIBRACOL™
Other · Device
Lead sponsor
Skye Biologics Holdings, LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 22, 2026, 7:32 PM EDT
Withdrawn Not applicable Interventional

An Evaluation of a Fibrillar Collagen Dressing to Treat Chronic, Stalled Lower-extremity Wounds

NCT03723577
View directory record Official record
Conditions
Wound
Interventions
Fibrillar collagen powder dressing
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 22, 2026, 7:32 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP

NCT02038257
View directory record Official record
Conditions
Vitiligo, Depigmented Scars, Depigmentation
Interventions
MKTP (melanocyte keratinocyte transplant procedure), Collagen Dressing, Vaseline Impregnated Gauze, Carbon Dioxide Laser, Dermabrasion
Procedure · Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 22, 2026, 7:32 PM EDT
Recruiting Not applicable Interventional

Patient-reported Outcomes of Donor Site Healing Using Different Palatal Protection Techniques

NCT06892496
View directory record Official record
Conditions
Mucosal Erosion, Gingival Recession
Interventions
Visual Analog scale (VAS) questionnaire, Vacuum-formed retainer (VFR) technique, 3-D printed acrylic resin stent (3DS) technique, Flowable resin composite stent (FRC) technique, Photographs of the patient's palate, Measuring graft dimensions, Chairside Polymer Stent
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 22, 2026, 7:32 PM EDT
Not listed Not applicable Interventional

Healing Chronic Venous Stasis Wounds With Autologous Cell Therapy

NCT02961699
View directory record Official record
Conditions
Wound, Nonpenetrating
Interventions
Transpose ® RT System, debridement/dressing of wound
Device · Other
Lead sponsor
InGeneron, Inc.
Industry
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Sep 22, 2026, 7:32 PM EDT
Recruiting No phase listed Observational

A Real-World Registry of Chronic Wounds and Ulcers

NCT02280733
View directory record Official record
Conditions
Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions
Usual care
Other
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
300,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction

NCT02844569
View directory record Official record
Conditions
Tooth Extraction
Interventions
Xenograft bone substitute, Collagen dressing, 3D-collagen matrix
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Sep 22, 2026, 7:32 PM EDT
Terminated Not applicable Interventional Results available

The Mechanism of Action of the Unite Biomatrix in Diabetic Foot Ulcer

NCT00958711
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Unite Biomatrix, Saline and Gauze
Device · Other
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
11
States / cities
San Diego, California • Miami, Florida • Evans, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SPT for Sensitization of Collagen Dressing

NCT06271993
View directory record Official record
Conditions
Allergy Skin, Allergic Skin Reaction
Interventions
ColActivePlus Collagen Matrix Dressing
Device
Lead sponsor
Covalon Technologies Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 22, 2026, 7:32 PM EDT
Completed Not applicable Interventional

Wound Dressings For Split-Thickness Skin Graft Donor Sites in Patients Undergoing Surgery

NCT01680367
View directory record Official record
Conditions
Pain, Perioperative/Postoperative Complications
Interventions
wound care management, questionnaire administration
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Sep 22, 2026, 7:32 PM EDT
Terminated Not applicable Interventional

PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.

NCT03502824
View directory record Official record
Conditions
Chronic Pressure Ulcers
Interventions
PuraPly® Antimicrobial Wound Matrix, SOC for Pressure Ulcers
Device · Other
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Lake Success, New York • Mineola, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Sep 22, 2026, 7:32 PM EDT