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Conditions: Pain, Postoperative
Interventions: Transdermal Lidocaine Patch, Transdermal Hydrocolloid Placebo Patch; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 59 Years · Female only
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Dental Crowding
Interventions: Nicotine, Placebo; Drug · Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Seasonal Allergic Rhinitis
Interventions: azelastine hydrochloride 0.15% Nasal Spray, azelastine hydrochloride 0.15% and Placebo, Azelastine 0.1%, Nasal Spray; Drug
Lead sponsor: Meda Pharmaceuticals; Industry
Eligibility: 12 Years and older
Enrollment: 617 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 30
States / cities: Fountain Valley, California • Long Beach, California • Los Angeles, California + 26 more

Conditions: Breast Cancer
Interventions: Breast surgery; Procedure
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 10
States / cities: Hartford, Connecticut • Ann Arbor, Michigan • Basking Ridge, New Jersey + 7 more

Conditions: Attention Difficulties
Interventions: Gel capsule; Other
Lead sponsor: PepsiCo Global R&D; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Cirrhosis, Liver, Acute Kidney Injury, Hepatorenal Syndrome
Interventions: Recommendation: No Further Resuscitation, Recommendation: Resuscitation with Crystalloid, Recommendation: Resuscitation with Colloid, Recommendation: Standard of Care IV Albumin; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Healthy
Interventions: Cefprozil for oral suspension 250 mg/5 mL, CEFZIL® for Oral Suspension 250 mg/5mL; Drug
Lead sponsor: Teva Pharmaceuticals USA; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004
U.S. locations: 2
States / cities: Saint Charles, Missouri • Houston, Texas

Conditions: Skin Manifestations
Interventions: metronidazole 1% gel, azelaic acid 15% gel; Drug
Lead sponsor: Galderma R&D; Industry
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Breast Cancer, Lymph Node Mapping, Sentinel Lymph Node Biopsy
Interventions: IC2000 and SPY-PHI, Tc-99m radioactive colloid and Gamma Probe; Combination Product
Lead sponsor: Novadaq Technologies ULC, now a part of Stryker; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 5
States / cities: Scottsdale, Arizona • Washington D.C., District of Columbia • Jacksonville, Florida + 2 more

Conditions: Cancer
Interventions: ETBX-021; Biological
Lead sponsor: NantBioScience, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: El Segundo, California • Sioux Falls, South Dakota

Conditions: LET, Laceration of Skin
Interventions: LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application), LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (3 applications); Drug
Lead sponsor: Children's Hospital of Orange County; Other
Eligibility: 7 Years to 18 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Orange, California

Conditions: Acne Vulgaris
Interventions: Internet survey, Benzoyl peroxide 5% gel; Behavioral · Drug
Lead sponsor: Wake Forest University; Other
Eligibility: 13 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, Stage IV Liver Cancer, Stage IVA Liver Cancer, Stage IVB Liver Cancer, Vascular Thrombosis
Interventions: Computed Tomography, Single Photon Emission Computed Tomography, Technetium Tc-99m Sulfur Colloid; Procedure · Drug
Lead sponsor: University of Washington; Other
Eligibility: 19 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 2
States / cities: Seattle, Washington

Conditions: Vesico-Ureteral Reflux
Interventions: Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]; Drug
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 6 Months to 35 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acne Vulgaris
Interventions: Dapsone Formulation A, Dapsone Formulation B, Dapsone Formulation C, Dapsone 5% Gel; Drug
Lead sponsor: Allergan; Industry
Eligibility: 16 Years to 35 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: College Station, Texas

Conditions: Acne Vulgaris
Interventions: Adapalene 0.3% / BPO 2.5% gel; Drug
Lead sponsor: Galderma R&D; Industry
Eligibility: 12 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Hypotension
Interventions: Colloid administration, Crystalloid administration, phenylephrine infusion; Other · Drug
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 35 Years · Female only
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Oral Lichen Planus, Oral Lichenoid Mucositis, Oral Lichenoid Reaction
Interventions: Ibuprofen suspension 5mg/100ml, Placebos; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Scleritis
Interventions: ACTH (adrenocorticotropic hormone) gel; Drug
Lead sponsor: Metropolitan Eye Research & Surgery Institute; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 3
States / cities: Palo Alto, California • Palisades Park, New Jersey • San Antonio, Texas

Conditions: Acne Vulgaris
Interventions: Topical Gel Vehicle, 8% NVN1000 Topical Gel, 8% NVN1000 Topical Gel and moisturizer; Drug
Lead sponsor: Novan, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Broomall, Pennsylvania

Conditions: Wounds and Injuries, Burns, Mohs Surgery, Diabetic Foot Ulcer Mixed, Venous Leg Ulcer, Non-healing Wound, Trauma Injury, Injury and Wounds, Degloving Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions: Various types of wound care treatments; Combination Product
Lead sponsor: Siddhey LLC; Industry
Eligibility: 18 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 12
States / cities: Scottsdale, Arizona • Tempe, Arizona • Tucson, Arizona + 8 more

Conditions: Perennial Allergic Rhinitis
Interventions: Olopatadine hydrochloride 0.6% nasal spray (PATANASE), Olopatadine nasal spray vehicle, pH 3.7, Olopatadine nasal spray vehicle, pH 7.0; Drug · Other
Lead sponsor: Alcon Research; Industry
Eligibility: 12 Years and older
Enrollment: 1,260 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Nonalcoholic Steatohepatitis, NASH - Nonalcoholic Steatohepatitis
Interventions: Tc 99M Sulfur Colloid, Tc99m-tilmanocept; Drug
Lead sponsor: Navidea Biopharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Kettering, Ohio

Conditions: HIV Infections
Interventions: Tenofovir 1% gel, Placebo gel; Drug · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 232 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Birmingham, Alabama • Pittsburgh, Pennsylvania

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The OBstetric Lidocaine Patch (OBLido) Trial

Nicotine as an Adjuvant Analgesic for Third Molar Surgery

A Study to Evaluate the Safety and Efficacy of a Nasal Spray to Treat Seasonal Allergies

Use of Sentinel Lymph Node Biopsy in Patients With Early-Stage, Palpable Node-Positive HR+/HER2- Breast Cancer Having Upfront Surgery and Adjuvant Radiation

Guayusa: The Effect of an Herbal Extract on Alertness and Mental Fatigue

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

Cefprozil for Oral Suspension 250 mg/5 mL, Fasting

Split-face Tolerability Comparison Between MetroGel® 1% vs Finacea® 15% in Subjects With Healthy Skin

A Study Assessing the Safety and Effectiveness of IC2000 and SPY Fluorescence Imaging Systems (SPY-PHI) in the Visualization of Lymphatic Vessels and Identification of Lymph Nodes During Sentinel Lymph Node Biopsy in Subjects With Breast Cancer

QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer

Comparison of 2 Application Techniques for LET Gel Used Prior to Simple Laceration Repair

A Novel Method to Improve Acne Outcomes

Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

Safety, Tolerability, and Pharmacokinetics of Dapsone in Acne Vulgaris

Subject Reported Outcomes With Use of Adapalene 0.3% - Benzoyl Peroxide (BPO) 2.5% in Dark Skin Acne

Spinal Anesthesia Induced Hypotension During Cesarean Section

Use of Topical NSAID to Reduce Pain in Oral Lichen Planus and Oral Lichenoid Lesions.

A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis

A Phase 1, 3 Day Study of Safety and Tolerability of NVN1000 Topical Gel in Healthy Volunteers

Clinical Registry Collecting Real World Evidence on Wound Care Treatments

Safety of PATANASE Nasal Spray in Patients With Perennial Allergic Rhinitis

Safety Evaluation of IV Tc 99m Tilmanocept and Comparison of Imaging With Sulfur Colloid in Subjects With and Without NASH

Tenofovir Gel in Pregnancy and Lactation