- Conditions
- Smoking Cessation
- Interventions
- Brief Advice, Motivational Interviewing, Rate Reduction, Pharmacological, MI+RR
- Behavioral · Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 903 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
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Showing 25–48
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- Conditions
- Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Persistent Depressive Disorder
- Interventions
- Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch, Smartphone coaching, Nicotine gum, Nicotine Lozenges
- Device · Behavioral · Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 343 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 3
- States / cities
- Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina
- Conditions
- Smoking Cessation
- Interventions
- NRT, Web Guide, Tweet2Quit
- Drug · Behavioral
- Lead sponsor
- University of California, Irvine
- Other
- Eligibility
- 21 Years to 59 Years
- Enrollment
- 980 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2022
- U.S. locations
- 2
- States / cities
- Irvine, California • Stanford, California
- Conditions
- Veterans, Tobacco Use Disorder, Cigarette Smoking, Tobacco Dependence
- Interventions
- Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT), Cessation-Phase Varenicline, Motivation-Phase Counseling, Cessation-Phase Counseling
- Drug · Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 21 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 4
- States / cities
- San Diego, California • Minneapolis, Minnesota • Durham, North Carolina + 1 more
- Conditions
- Smoking Cessation
- Interventions
- Nicotine Patches, Nicotine patches, then bupropion & nicotine patches (Pre-Quit), Nicotine patches, then varenicline (Pre-Quit), Nicotine patches, then nicotine patches (Pre-Quit), Nicotine patches, then bupropion & nicotine patches (Post-Quit), Nicotine patches, then varenicline (Post-Quit), Nicotine patches, then nicotine patches (Post-Quit)
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 606 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 1
- States / cities
- Charlotte, Durham, Raleigh, Winston-Salem, North Carolina
- Conditions
- Cigarette Smoking, Overweight, Obesity
- Interventions
- Weight gain prevention and smoking cessation, Smoking cessation
- Behavioral
- Lead sponsor
- Consumer Wellness Solutions
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 2,540 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Cancer
- Interventions
- TTM Tailored, Motivational Enhancement Therapy, Integrated Treatment
- Behavioral
- Lead sponsor
- University of Rhode Island
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2013
- U.S. locations
- 1
- States / cities
- Kingston, Rhode Island
- Conditions
- Tobacco Use Disorder
- Interventions
- Bupropion
- Drug
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 589 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2000 – 2006
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ST+ABR, ST+SHAM, ST-only
- Interventions
- ST+ABR, ST+Sham, ST Only
- Behavioral
- Lead sponsor
- University of Houston
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Nicotine Dependence
- Interventions
- Preparation Varenicline and Standard Duration Varenicline, Preparation Varenicline and Extended Duration Varenicline, Standard Duration Varenicline, Extended Duration Varenicline, Preparation Combination NRT and Standard Duration Combination NRT, Preparation Combination NRT and Extended Duration Combination NRT, Standard Duration Combination NRT, Extended Duration Combination NRT, Intensive Counseling, Minimal Counseling
- Drug · Behavioral
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 538 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2025
- U.S. locations
- 2
- States / cities
- Madison, Wisconsin • Milwaukee, Wisconsin
- Conditions
- Tobacco Use
- Interventions
- e-cigarette, Nicotine patch, Nicotine lozenge
- Behavioral · Other
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Tobacco Use, Substance Use Disorders
- Interventions
- Switching to E-Cigarette, Quitting using Medication, Counseling
- Behavioral · Drug
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 4
- States / cities
- Charleston, South Carolina • Conway, South Carolina • Greenville, South Carolina + 1 more
- Conditions
- Smoking Cessation
- Interventions
- Automated Mobile Contingency Management (CM), Standard Care (SC)
- Behavioral · Other
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 532 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Cigarette Smoker, Tobacco Use Disorder
- Interventions
- Nicotine Lozenge, Nicotine Patch, Placebo, Tobacco Cessation Counseling, Varenicline
- Drug · Other
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 631 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Tobacco Use Disorder
- Interventions
- ModafinilNicotine Replacement Therapy, Modafinil
- Drug
- Lead sponsor
- Catherine Martin, MD
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2011
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Smokeless Tobacco, Nicotine Dependence
- Interventions
- Tailored behavioral intervention, Behavioral activation for elevated depressive symptoms, Post-cessation weight gain management, Alcohol use risk reduction, Nicotine replacement therapy - transdermal nicotine patch, Nicotine replacement therapy - nicotine lozenge, Nicotine replacement therapy - nicotine gum, Bupropion sustained release, Varenicline, Combination nicotine replacement therapy, Combination nicotine replacement therapy + bupropion, Tobacco quit line, Educational materials
- Behavioral · Drug
- Lead sponsor
- Mark Vander Weg
- Federal
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 123 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Smoking, Alcoholism
- Interventions
- Cognitive Behavior Therapy for alcohol and smoking cessation, Nicoderm CQ nicotine patch, Placebo gum, Nicotine gum - Nicorette®
- Behavioral · Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2006
- U.S. locations
- 1
- States / cities
- Newington, Connecticut
- Conditions
- HIV/AIDS
- Interventions
- Storytelling Narrative Intervention
- Combination Product
- Lead sponsor
- University of Massachusetts, Boston
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 53 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Smoking Cessation
- Interventions
- Quitline Treatment (QT), App-based Treatment (mHealth)
- Other
- Lead sponsor
- H. Lee Moffitt Cancer Center and Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 3
- States / cities
- Coral Gables, Florida • Gainesville, Florida • Tampa, Florida
- Conditions
- Alcohol Drinking
- Interventions
- 21mg transdermal nicotine patch (Nicoderm CQ), 1mg nicotine nasal spray, placebo nasal spray
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2016
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm, Recurrent Neoplasm, Smoking Cessation
- Interventions
- Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment, Survey Administration, Tobacco Cessation Counseling
- Other · Drug
- Lead sponsor
- ECOG-ACRIN Cancer Research Group
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 306 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 42
- States / cities
- Anchorage, Alaska • Atlanta, Georgia • Augusta, Georgia + 32 more
- Conditions
- Smoking Cessation, Cervical Cancer, High Grade Cervical Dysplasia
- Interventions
- Smoking Cessation treatment delivered by Tobacco Free Florida Quitline, Nicotine patch, Nicotine Lozenge, Motivation and Problem Solving (MAPS) intervention
- Behavioral · Drug
- Lead sponsor
- H. Lee Moffitt Cancer Center and Research Institute
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Tobacco Use Cessation
- Interventions
- Nicoderm CQ 21Mg/24Hr Transdermal System
- Drug
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 49 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Smoking, Smoking Cessation, HIV
- Interventions
- Nicoderm C-Q Transdermal Product, Adherence to Antiretroviral Therapy Counseling, Behavioral Smoking Cessation Counseling, "Crave-to-Quit" app, vDOT "emocha" app
- Drug · Behavioral
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Miami, Florida