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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Conditions
E Cigarette Use, Cessation, Tobacco, Cessation, Nicotine
Interventions
Nicotine Replacement Therapies, Brief Behavioral Counseling
Drug · Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Greenville, North Carolina • Morgantown, West Virginia
Conditions
Remote vs. In-Person, Remote Visits, In-person Visits
Interventions
Combination Nicotine Replacement Therapy (patch and lozenge)
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Buffalo, New York • Philadelphia, Pennsylvania
Completed Phase 2 Interventional Accepts healthy volunteers Results available

UW Withdraw From Tobacco Study

NCT04969198
Conditions
Tobacco Dependence
Interventions
Combination nicotine replacement therapy (Nicotine patch + nicotine mini-lozenge)
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years and older
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Cigarette Smoking, Veterans
Interventions
Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling, Healthy Changes Counseling
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Research and Innovation to Stop E-cigarette/Vaping in Young Adults

NCT04974580
Conditions
Nicotine Dependence, E-Cig Use
Interventions
Nicotine patch, Phone Counseling, Digital Coaching
Drug · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 24 Years
Enrollment
508 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Smoking, Pulmonary Disease, Chronic Obstructive, Tobacco Use Disorder
Interventions
Standard Smoking Cessation, Extended Nicotine Replacement Therapy, Nicotine replacement therapy
Other · Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Tobacco Use Cessation
Interventions
Nicoderm CQ 21Mg/24Hr Transdermal System
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Genetically Informed Smoking Cessation Trial

NCT02351167
Conditions
Smoking Cessation
Interventions
Combination NRT (Nicotine patch, Nicotine lozenge), Varenicline, Placebo, Intensive smoking counseling
Drug · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older
Enrollment
822 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Contingency Management for Smoking Cessation

NCT04881630
Conditions
Smoking Cessation
Interventions
Automated Mobile Contingency Management (CM), Standard Care (SC)
Behavioral · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Improving Quitline Support Study

NCT03538938
Conditions
Tobacco Use Cessation
Interventions
1-Call Quitline Counseling, 4-Call Quitline Counseling, Nicotine patch, Nicotine Patch and Nicotine Lozenge, SmokefreeTXT, No SmokefreeTXT, Financial Incentives for Treatment Engagement, No Financial Incentives for Treatment Engagement
Behavioral · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
1,316 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

Quit or Switch: E-cigarette Study

NCT05525078
Conditions
Tobacco Use
Interventions
e-cigarette, Nicotine patch, Nicotine lozenge
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Smoking Cessation
Interventions
Contingency management, Nicotine replacement therapy, Varenicline, Additional behavioral support
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Phase 2Phase 3 Interventional Results available

CPT and Smoking Cessation

NCT01901848
Conditions
Stress Disorders, Post-Traumatic, Smoking
Interventions
Cognitive Processing Therapy (CPT), Bupropion, nicotine replacement therapy (NRT), Integrated Care for Smoking Cessation (ICSC), smokefreeVET
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Offering Proactive Tobacco Treatment

NCT01123967
Conditions
Tobacco Use Cessation
Interventions
proactive outreach (PRO), telephone counseling (TC), Nicotine replacement therapy (NRT), Usual care (UC)
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, Persistent Depressive Disorder
Interventions
Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch, Smartphone coaching, Nicotine gum, Nicotine Lozenges
Device · Behavioral · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers

NCT05136430
Conditions
Smoking Cessation, Obesity
Interventions
Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Recruiting Not applicable Interventional Accepts healthy volunteers

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

NCT06922617
Conditions
Tobacco Use, Substance Use Disorders
Interventions
Switching to E-Cigarette, Quitting using Medication, Counseling
Behavioral · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
4
States / cities
Charleston, South Carolina • Conway, South Carolina • Greenville, South Carolina + 1 more
Conditions
Smoking Cessation
Interventions
Standard Care (SC), Intensive Counseling (IC)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York
Conditions
Smoking Cessation
Interventions
Phone-based Tobacco Treatment, Nicotine Replacement, and Stepped Care Intervention, E-Referral to the Tobacco Quitline
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
50 Years to 80 Years
Enrollment
1,188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Opioid Use Disorder, Cigarette Smoking
Interventions
Telehealth Motivational Counseling, Nicotine Replacement Product, National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).
Behavioral · Drug · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Tailored Tobacco Quitline for Rural Veterans

NCT01592695
Conditions
Cigarette Smoking
Interventions
Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral, Nicotine replacement therapy - nicotine gum, Nicotine replacement therapy - nicotine lozenge, Bupropion Sustained Release, Varenicline, Combination pharmacotherapy - transdermal nicotine patch + nicotine gum, Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge, Combination pharmacotherapy - transdermal nicotine patch + bupropion, Alcohol use risk reduction, Behavioral activation for the treatment of depression, Behavioral management of post-cessation weight gain
Drug · Behavioral
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Smoking Cessation, Cervical Cancer, High Grade Cervical Dysplasia
Interventions
Smoking Cessation treatment delivered by Tobacco Free Florida Quitline, Nicotine patch, Nicotine Lozenge, Motivation and Problem Solving (MAPS) intervention
Behavioral · Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Not listed Not applicable Interventional Accepts healthy volunteers

Treating Smokeless Tobacco Use in Rural Veterans

NCT02994082
Conditions
Smokeless Tobacco, Nicotine Dependence
Interventions
Tailored behavioral intervention, Behavioral activation for elevated depressive symptoms, Post-cessation weight gain management, Alcohol use risk reduction, Nicotine replacement therapy - transdermal nicotine patch, Nicotine replacement therapy - nicotine lozenge, Nicotine replacement therapy - nicotine gum, Bupropion sustained release, Varenicline, Combination nicotine replacement therapy, Combination nicotine replacement therapy + bupropion, Tobacco quit line, Educational materials
Behavioral · Drug
Lead sponsor
Mark Vander Weg
Federal
Eligibility
18 Years to 99 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices

NCT03808818
Conditions
Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm, Recurrent Neoplasm, Smoking Cessation
Interventions
Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment, Survey Administration, Tobacco Cessation Counseling
Other · Drug
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
42
States / cities
Anchorage, Alaska • Atlanta, Georgia • Augusta, Georgia + 32 more