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Showing 1–24 of 156 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Combined Diet and Exercise Clear all
Recruiting Not applicable Interventional

Trial of Exercise and Lifestyle for Women With Ovarian and Endometrial Cancer

NCT05761561
View directory record Official record
Conditions
Ovarian Cancer
Interventions
Exercise and medical nutrition
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 18, 2026, 10:56 PM EDT
Terminated Not applicable Interventional

Smartphone GUIded MeDication AdherencE and Rehabilitation in Patients With Coronary Artery Disease

NCT03207646
View directory record Official record
Conditions
Coronary Artery Disease, Acute Coronary Syndrome
Interventions
BrightHeart®
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Individual Counseling and/or Computer-Based Counseling in Helping Healthy Women Adopt a Cancer Prevention Diet

NCT00217490
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
dietary counseling via computer, dietary counseling via nutritionist, combined computer and nutritionist, physical activity counseling via computer
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
30 Years to 70 Years · Female only
Enrollment
621 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
3
States / cities
Aurora, Colorado • Eugene, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Sep 18, 2026, 10:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Resistance Training Intervention to Improve Physical Function in Patients With Pancreatic Cancer Receiving Combination Chemotherapy or Have Undergone Surgery, PancStrength Study

NCT04837118
View directory record Official record
Conditions
Advanced Pancreatic Adenocarcinoma, Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8
Interventions
Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration, Resistance Training
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

Using Mobile Technology to Improve Self-Regulation

NCT03774433
View directory record Official record
Conditions
Self-regulation, Binge Eating, Smoking
Interventions
Laddr
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Sep 18, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females

NCT07546591
View directory record Official record
Conditions
Iron Deficiencies, Low Ferritin, Iron Deficiency, Exercise Performance of Fit Athletes
Interventions
Lactoferrin 100 mg, Lactoferrin 300 mg, Iron Supplementation (5 mg)
Dietary Supplement
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

Telephone Delivered Behavioral Skills Intervention for Blacks With T2DM

NCT00929838
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Noninsulin Dependent, Diabetes Mellitus, Type II
Interventions
Diabetes Knowledge/Information, Motivation/Behavioral Skills, Combined Intervention, Usual Care
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-compassion and Nutrition (SCAN) Study

NCT04289636
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Behavioral weight loss program, Self-compassion, Nutrition and cooking education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 30, 2021 · Synced Sep 18, 2026, 10:56 PM EDT
Active, not recruiting Not applicable Interventional

Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension

NCT07130539
View directory record Official record
Conditions
Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
Interventions
MIND HIIT
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 74 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 18, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study

NCT07146412
View directory record Official record
Conditions
Cognitive Impairment, Alzheimer Blood Biomarkers, Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Interventions
Multimodal Lifestyle Intervention
Behavioral
Lead sponsor
HudsonAlpha Institute for Biotechnology
Other
Eligibility
65 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Computerized Anxiety Treatment for Suicide

NCT01990131
View directory record Official record
Conditions
Anxiety, Suicide
Interventions
Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 8, 2016 · Synced Sep 18, 2026, 10:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0

NCT05553925
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Online Weight Management Program with Coaching and Patient Navigator Support
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

TRE With Physical Activity for Weight Management

NCT04978376
View directory record Official record
Conditions
Pre Diabetes, Overweight and Obesity
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

Texting for Mobility in Overweight/Obese Adults With Peripheral Artery Disease

NCT03694652
View directory record Official record
Conditions
Overweight and Obesity
Interventions
PACE, Diet, App, Face-to-face
Behavioral · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
50 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-Induced Epigenetic Modifications in Obese Aging Women

NCT01977885
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
High Protein Diet, Exercise
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
50 Years to 64 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

NCT04221750
View directory record Official record
Conditions
Frailty, Sarcopenic Obesity, Aging
Interventions
Lifestyle therapy, Metformin Hydrochloride, Placebo, Healthy Lifestyle
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Building an Evidence Base for Weight Loss Strategies Among Those With Chronic SCI-The GLB-SCI+

NCT03874988
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Weight Loss, Diet Modification
Interventions
Portion-Controlled Meals, Enhanced Self-Monitoring, GLB-SCI+
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Phase 2 Interventional

Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM

NCT01658501
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
50 mg PB1023, 70 mg PB1023, 100 mg PB1023, Placebo (0.9% Sodium Chloride), Victoza®, Diet and Exercise, Metformin, Sulfonylurea, Metformin and Sulfonylurea
Drug · Other
Lead sponsor
PhaseBio Pharmaceuticals Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
593 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
93
States / cities
Anniston, Alabama • Birmingham, Alabama • Gulf Shores, Alabama + 90 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2015 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

Behavioral Weight Loss and Stigma Reduction

NCT03704064
View directory record Official record
Conditions
Obesity
Interventions
Stigma-Reduction Intervention, Behavioral Weight Loss (BWL)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Sep 18, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional

Building Connections

NCT07091032
View directory record Official record
Conditions
Cancer Colorectal, Cancer Cervix, Depression, Anxiety, Obesity
Interventions
Treatment as Usual, Building Connections Intervention
Other · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
3,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Sep 18, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

NCT06298734
View directory record Official record
Conditions
Melanoma (Skin), Skin Cancer, Advanced Melanoma
Interventions
Exercise Program, Diet Program
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Piloting Text Messages to Promote Positive Affect and Physical Activity

NCT04077229
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Intervention arm: Text Message Intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Sep 18, 2026, 10:56 PM EDT
Not yet recruiting Phase 4 Interventional

Nutrition Intervention Combined With Resmetirom for MASH

NCT07680478
View directory record Official record
Conditions
Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Interventions
Resmetirom therapy, Comprehensive nutritional intervention, Standard dietary support
Drug · Behavioral
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 18, 2026, 10:56 PM EDT
Completed Phase 3 Interventional Results available

A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

NCT00327015
View directory record Official record
Conditions
Diabetes
Interventions
Saxagliptin, Metformin, Placebo, pioglitazone
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 77 Years
Enrollment
1,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
47
States / cities
Concord, California • Encinitas, California • Orange, California + 38 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 18, 2026, 10:56 PM EDT