- Conditions
- Smoking Behaviors
- Interventions
- IQOS, Smoking as Usual
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 21 Years to 77 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
Search Results
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Smoking Cessation
- Interventions
- Bupropion, Zonisamide, Placebo bupropion, Placebo zonisamide, E-cigarette
- Drug · Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Smoking Cessation, Harm Reduction
- Interventions
- d-cycloserine, Juul e-cigarette
- Drug · Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Cigarette Smoking
- Interventions
- Market Price Condition (control), Tobacco Parity Tax Condition, Nicotine-Content Tax Condition, Harm-Reduction Tax Condition, Modified Risk Tobacco Product (MRTP) Tax Condition
- Behavioral
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 285 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 2
- States / cities
- Buffalo, New York • Roanoke, Virginia
- Conditions
- Smoking Cessation
- Interventions
- BIDI Stick e-cigarette
- Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Electronic Cigarette Use, Cigarette Use, Electronic, Tobacco Use, Tobacco Smoking
- Interventions
- Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Mint ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Menthol ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Menthol ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Mango ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Mango ENDS, Switch to Dual-use of JUUL 5% and UB of Combustible Cigarette, Tobacco/Nicotine Abstention, Usual Brand of cigarettes
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 279 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 5
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • St Louis, Missouri + 2 more
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Interventions
- High Nicotine Dose, Low Nicotine Dose
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Cigarette Smoking
- Interventions
- Harm Reduction Tax - Normal Nicotine Cigarettes Available, Harm Reduction Tax - Normal Nicotine Cigarettes Not Available, Modified Risk Tobacco Product Tax - Normal Nicotine Cigarettes Available, Modified Risk Tobacco Product Tax - Normal Nicotine Cigarettes Not Available, Nicotine Content Tax - Normal Nicotine Cigarettes Available, Nicotine Content Tax - Normal Nicotine Cigarettes Not Available, Tobacco Parity Tax - Normal Nicotine Cigarettes Available, Tobacco Parity Tax - Normal Nicotine Cigarettes Not Available
- Behavioral
- Lead sponsor
- Virginia Polytechnic Institute and State University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 316 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Buffalo, New York • Roanoke, Virginia
- Conditions
- Smoking Cessation, Smoking Behaviors, Smoking Reduction, Smoking, Cigarette, Smoking, Nicotine Dependence
- Interventions
- Clickotine®
- Device
- Lead sponsor
- Click Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Tobacco Smoking, Psychiatric Disorders
- Interventions
- E-cigarette
- Other
- Lead sponsor
- Fordham University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Electronic Cigarette Use
- Interventions
- Health Assessments
- Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Smoking
- Interventions
- P3L, VUSE, CC
- Other
- Lead sponsor
- Philip Morris Products S.A.
- Industry
- Eligibility
- 19 Years to 65 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Raleigh, North Carolina
- Conditions
- Electronic Cigarette Use, Cigarette Use, Electronic, Tobacco Use, Tobacco Smoking
- Interventions
- JUUL ENDS 5% Virginia Tobacco, JUUL 3% Virginia Tobacco ENDS, JUUL 5% Mint ENDS, JUUL 3% Mint ENDS, JUUL 5% Menthol ENDS, JUUL 3% Menthol ENDS, JUUL 5% Mango ENDS, JUUL 3% Mango ENDS, US Cigarette, Non-menthol - Marlboro Gold King Size, US Cigarette, Menthol - Newport King Size
- Other
- Lead sponsor
- Juul Labs, Inc.
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 3
- States / cities
- Secaucus, New Jersey • Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
- Interventions
- Product A, Product B, Product C, Product D, Product E
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Knoxville, Tennessee
- Conditions
- Obesity, Smoking Cessation
- Interventions
- ENDS, CI, No ENDS, NI
- Other
- Lead sponsor
- Brown University
- Other
- Eligibility
- 21 Years to 99 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Tobacco Use
- Interventions
- Product A, Product B, Product C, Product D, Product E, Product F
- Other
- Lead sponsor
- Altria Client Services LLC
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 3
- States / cities
- Lexington, Kentucky • Springfield, Missouri • Knoxville, Tennessee
- Conditions
- Smoking, Tobacco
- Interventions
- P2613422, P2611222, P2615522, P2615122, P2615422
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 1,280 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 7
- States / cities
- Maitland, Florida • Atlanta, Georgia • St Louis, Missouri + 4 more
- Conditions
- Smoking Cessation, Vaping Cessation
- Interventions
- Cytisinicline
- Drug
- Lead sponsor
- Achieve Life Sciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 479 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 29
- States / cities
- Mobile, Alabama • Tempe, Arizona • Little Rock, Arkansas + 26 more
- Conditions
- Hiv, Lung Injury
- Interventions
- Not listed
- Lead sponsor
- Pennington Biomedical Research Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 2
- States / cities
- Baton Rouge, Louisiana • New Orleans, Louisiana
- Conditions
- Cannabis Use, Tobacco Use, Cigarette Smoking
- Interventions
- THC 30mg, THC 5mg, THC 0mg, Cigarette Full Nicotine, Cigarette Reduced Nicotine
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Smoking Cessation, Harm Reduction, E-Cig Use, Cigarette Smoking, Tobacco Dependence, Tobacco Use Cessation
- Interventions
- JUUL
- Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Healthy Volunteers
- Interventions
- Combustible Cigarette, blu Disposable A, blu Disposable B, blu Disposable C, blu Disposable D, blu Disposable E
- Other
- Lead sponsor
- Fontem US LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Burbank, California
- Conditions
- Tobacco Use
- Interventions
- Behavioral and pharmacological support to reduce combustible tobacco use.
- Behavioral
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Tobacco Use
- Interventions
- Brief behavioral counseling
- Behavioral
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois