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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Computerized Cognitive Remediation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode

NCT02267070
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
Interventions
Case management and supportive psychotherapy, Family psychoeducation, Cognitive training, Aerobic exercise
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode

NCT02823041
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
Interventions
Cognitive Training, Aerobic Exercise, Case management and supportive psychotherapy, Individual Placement and Support
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2023 · Synced Sep 2, 2026, 6:45 AM EDT
Not listed Not applicable Interventional

Computerized Cognitive Exercise Training Treatment for Adults With Multiple Sclerosis

NCT02141386
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
PACR (Plasticity-based, Adaptive, Computerized Cognitive Remediation)
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Phase 2 Interventional

Evaluation of a Cognitive Adaptive E-treatment in Schizophrenia-diagnosed Adults

NCT01422902
View directory record Official record
Conditions
Schizophrenia
Interventions
Plasticity-based Cognitive Training, Non-plasticity-based Training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Palo Alto, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Results available

Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention

NCT03373240
View directory record Official record
Conditions
Drug Use Disorders
Interventions
TAU plus Cognitive Remediation Program, TAU plus Control Tasks
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 7, 2021 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Treatment Response to Rehabilitation in Patients With Schizophrenia

NCT00063336
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive Remediation, Computer-skills training
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 7, 2013 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Results available

A Novel Neurorehabilitation Approach for Cognitive Aging With HIV

NCT02391311
View directory record Official record
Conditions
HIV, Aging
Interventions
transcranial direct current stimulation (tDCS)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Results available

Cognitive Behavior Therapy and Work Outcome

NCT00810355
View directory record Official record
Conditions
Schizophrenia
Interventions
Support Group, Cognitive Behavior Therapy, Cognitive Remediation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Phase 3 Interventional Results available

Efficacy of Cognitive Remediation in Patients With Schizophrenia or Schizoaffective Disorder Stabilized on Lurasidone

NCT01173874
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive Remediation
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
16
States / cities
Granada Hills, California • Orange, California • New Haven, Connecticut + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Performance-based Reinforcement to Enhance Cognitive Remediation Therapy

NCT01633138
View directory record Official record
Conditions
Substance-Related Disorders, Mental Disorders
Interventions
Cognitive Remediation Therapy - Standard, Cognitive Remediation Therapy plus Contingency Management
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Neuroplasticity-Based Cognitive Remediation for Chemotherapy-Related Cognitive Impairment

NCT04230863
View directory record Official record
Conditions
Cancer Survivors, Chemotherapy-related Cognitive Impairment
Interventions
Neuroplasticity-based Computerized Cognitive Remediation
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
35 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Sep 2, 2026, 6:45 AM EDT
Not listed Not applicable Interventional

Comparing Cognitive Remediation Approaches for Schizophrenia

NCT04123223
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Cognitive Remediation, Computer Games
Behavioral
Lead sponsor
Wesleyan University
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Hartford, Connecticut • Middletown, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia

NCT01773239
View directory record Official record
Conditions
Schizophrenia
Interventions
TARA computer-based exercises
Behavioral
Lead sponsor
Posit Science Corporation
Industry
Eligibility
18 Years to 35 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Remediation to Improve Mobility in Sedentary Seniors

NCT02567227
View directory record Official record
Conditions
Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
Interventions
Cognitive Remediation, Active Control
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
70 Years and older
Enrollment
383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Brain Activation Patterns in Schizophrenia After Computerized Cognitive Skills Training

NCT00431223
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive remediation therapy
Behavioral
Lead sponsor
Manhattan Psychiatric Center
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Brain-Training Treatment for Long COVID in Older Adults

NCT05705193
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome
Interventions
NeuroFlex (computerized gamified tasks)
Other
Lead sponsor
UConn Health
Other
Eligibility
60 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plasticity-based Adaptive Cognitive Remediation for Alzheimer Disease

NCT02331784
View directory record Official record
Conditions
Older Adults, Aging Brain
Interventions
Computerized Plasticity-based Software, Commercially available Video Game
Behavioral
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years to 79 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 2, 2026, 6:45 AM EDT
Recruiting Not applicable Interventional

Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.

NCT04349852
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
BrainHQ Cognitive Training Modules, BrainHQ People Skills Modules
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional Results available

Cognitive Training and tDCS for Children With FASD

NCT03361293
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders
Interventions
Active tDCS, Cognitive training, Sham tDCS
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 16 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Sep 2, 2026, 6:45 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

An Assessment of Cognitive Improvement Training Among Mid-life Individuals

NCT03501706
View directory record Official record
Conditions
Delay Discounting
Interventions
Sequenced Recall of Digits--Auditory, Sequenced Reverse Recall of Digits--Auditory, Sequenced Recall of Words--Visual, Verbal Memory--Visual
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
40 Years to 60 Years
Enrollment
680 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Sep 2, 2026, 6:45 AM EDT
Active, not recruiting Not applicable Interventional

nCCR for Chemotherapy Related Cognitive Impairment Randomized Study

NCT05283629
View directory record Official record
Conditions
Chemo-brain, Chemotherapy-Related Cognitive Impairment
Interventions
Neuroplasticity-based Computerized Cognitive Remediation, Active Control Condition
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
35 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Phase 2Phase 3 Interventional

The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder

NCT04318639
View directory record Official record
Conditions
Alcohol Use Disorder, Mild Cognitive Impairment
Interventions
Donepazil
Combination Product
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
21 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 2, 2026, 6:45 AM EDT
Completed Not applicable Interventional

Remediation of Visual Perceptual Impairments in People With Schizophrenia

NCT03314129
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
UltimEyes, Contour Integration Training, UltimEyes + Contour Integration Training, MyBrainSolutions
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 60 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Rochester, New York • White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 2, 2026, 6:45 AM EDT
Not yet recruiting Not applicable Interventional

Cognitive Enhancement in Recurrent Depression (The COG-D-R Study)

NCT07527273
View directory record Official record
Conditions
Aging, Depression, Cognitive Symptoms
Interventions
Depression Cognitive Training, Non-Specific Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation)
Behavioral · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 2, 2026, 6:45 AM EDT