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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:02 AM EDT

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Showing 241–263 of 263 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Computerized Cognitive Training Clear all
Terminated Not applicable Interventional

tDCS and Metacognitive Strategy Training in Stroke

NCT05248178
View directory record Official record
Conditions
Chronic Stroke
Interventions
CO-OP Procedures, tDCS, Computer Cognitive Training Procedures, sham tDCS group
Behavioral · Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Withdrawn Not applicable Interventional

Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Interictal Dysfunction in Epilepsy

NCT02950506
View directory record Official record
Conditions
Epilepsy
Interventions
transcranial direct current stimulation, Cognitive Remediation Therapy
Device · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Cognitive Flexibility Training in Persistent Pain

NCT03398408
View directory record Official record
Conditions
Chronic Pain
Interventions
Training
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2020 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Brain-Training Treatment for Long COVID in Older Adults

NCT05705193
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome
Interventions
NeuroFlex (computerized gamified tasks)
Other
Lead sponsor
UConn Health
Other
Eligibility
60 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

A Health Game Intervention for Cancer and Post-ICU Patients Suffering From Acute Cognitive Impairment

NCT07596940
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
VR cognitive training platform
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy

NCT07098169
View directory record Official record
Conditions
Schizophrenia Disorders, Schizoaffective Disorder, Psychotic Disorder
Interventions
iTEST, Active Control
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
San Diego, California • Miami, Florida • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HARP-Project 1 Cognitive Training

NCT03293823
View directory record Official record
Conditions
Aging, Social Isolation
Interventions
VSOP training, MLA control
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
4
States / cities
Fairport, New York • Pittsford, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 21, 2026, 7:02 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

A Novel Computer-Based Functional Skills Assessment and Training Program

NCT04679441
View directory record Official record
Conditions
Mild Cognitive Impairment, Healthy Aging
Interventions
The Computerized Functional Skills Assessment and Training Program, Brain HQ Double Decision
Device
Lead sponsor
i-Function, Inc.
Industry
Eligibility
60 Years to 100 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Miami, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Cognitive Training in Mild Cognitive Impairment

NCT04899089
View directory record Official record
Conditions
Insomnia, Mild Cognitive Impairment
Interventions
Cognitive Training, Trivia Training
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
60 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromodulation of Cognition in Older Adults

NCT02137122
View directory record Official record
Conditions
Healthy
Interventions
Sham Stimulation, Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 90 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Psychosocial Therapy and Risperidone Treatment in Work Performance in Recent-Onset Schizophrenia

NCT00333177
View directory record Official record
Conditions
Schizophrenia
Interventions
Cognitive remediation training (CT), Healthy behavior training (HBT), Risperidone, administered orally (Oral Ris), Risperidone, administered via injection (RLAI)
Behavioral · Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Oct 21, 2026, 7:02 AM EDT
Terminated Not applicable Interventional

Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease

NCT05978804
View directory record Official record
Conditions
Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
Interventions
Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC
Other · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Video Game-Brain Functioning Reversibility Study

NCT00700453
View directory record Official record
Conditions
Brain Functioning and Violent Video Game Play
Interventions
Control group with no video game play, control 2, VG1 group (2 weeks of violent video game play), Cognitive Training
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 3, 2012 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Remote Digital Health Intervention to Improve Balance and Reduce Fall Risk

NCT05022589
View directory record Official record
Conditions
Fall
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Not listed Phase 2 Interventional

Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease

NCT05122598
View directory record Official record
Conditions
Mild Cognitive Impairment, Early Alzheimer's Disease, Memory Impairment
Interventions
COT, Sham
Drug
Lead sponsor
Evon Medics LLC
Industry
Eligibility
55 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Phase 4 Interventional

Cognitive Skills Training Using Computer for Patients With Severe Mental Illness

NCT01036282
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Computerized Cognitive Skill Training, CRT and Social Cognition
Behavioral
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years and older
Enrollment
448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 21, 2026, 7:02 AM EDT
Terminated Not applicable Interventional Results available

Auditory Control Enhancement (ACE) in Schizophrenia

NCT06155695
View directory record Official record
Conditions
Auditory Hallucinations
Interventions
Transcranial Direct Current Stimulation (tDCS), Auditory Cognitive Control Training (ACCT)
Device · Behavioral
Lead sponsor
Brian A Coffman, PhD
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Preventing Alzheimer's With Cognitive Training

NCT03848312
View directory record Official record
Conditions
Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
Interventions
Cognitive Training, Computerized Cognitive Stimulation
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
65 Years and older
Enrollment
7,600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
7
States / cities
Gainesville, Florida • Jacksonville, Florida • Sarasota, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

NCT04171323
View directory record Official record
Conditions
Age-related Cognitive Decline, Mild Cognitive Impairment, Dementia
Interventions
Cognitive Training, Computerized Cognitive Stimulation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years to 89 Years
Enrollment
1,305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
6
States / cities
San Francisco, California • Gainesville, Florida • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Personalized Computerized Inhibitory Control Training for OCD

NCT02378896
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Personalized Computer Program, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 21, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode

NCT05890183
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
Interventions
Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST), Chorus Participatory Text Messaging Program, Healthy Living Group (HLG)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Understanding How Cognitive Remediation Works

NCT01683539
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Chronic Mental Disorder, Major Depression, Bipolar Disorder
Interventions
The Thinking Skills for Work Program, The Cognitive Skills for Work Program
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Chicago, Illinois • Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 21, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Treatment of Social Cognition in Schizophrenia Trial

NCT02246426
View directory record Official record
Conditions
Schizophrenia
Interventions
Computerized plasticity-based adaptive cognitive training, Commercially available computerized training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Oct 21, 2026, 7:02 AM EDT