- Conditions
- Chronic Low-back Pain
- Interventions
- Algorithmically informed randomization (taking into account phenotypes), Physical Therapy (PT) and Exercise, Cognitive-Behavioral Therapy for Pain (PRISM-CBT), mHealth Acupressure Self-Management:, Duloxetine
- Device · Behavioral · Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 25 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
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Showing 1–24
of 44
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Toothache, Temporomandibular Joint Disorders
- Interventions
- Pressure pain threshold
- Procedure
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 39 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Migraine
- Interventions
- Nerivio (REN device)
- Device
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 8 Years and older
- Enrollment
- 2,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Chronic Temporomandibular Disorders (TMD)
- Interventions
- Pain modulation testing
- Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Migraine
- Interventions
- Nerivio REN device
- Device
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 8 Years and older
- Enrollment
- 332 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Pain
- Interventions
- Thermal Sensory Analyzer, Pressure Stimuli, Mechanical Stimuli, Pain Ratings, Thermal pain thresholds, Pressure pain thresholds (PPT), Mechanical temporal summation, Conditioned pain modulation (CPM) efficiency, Offset analgesia efficiency, Cold pain tolerance
- Device · Behavioral
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 9 Years to 16 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Migraine, Pregnancy Related
- Interventions
- Nerivio, Migraine Relief
- Device · Drug
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 18 Years to 42 Years · Female only
- Enrollment
- 145 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 2
- States / cities
- San Diego, California • Montclair, New Jersey
- Conditions
- Neck Pain Musculoskeletal, Chronic
- Interventions
- Spinal mobilization (SM) of the neck
- Procedure
- Lead sponsor
- Azusa Pacific University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Azusa, California
- Conditions
- Migraine, Acute Treatment of Migraine
- Interventions
- Nerivio REN device
- Device
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 466 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Acute Migraine
- Interventions
- Nerivio
- Device
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 12 Years to 17 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 12
- States / cities
- Aurora, Colorado • Hialeah, Florida • Miami, Florida + 8 more
- Conditions
- Migraine, Endometriosis
- Interventions
- Thermal stimuli, Pressure stimuli, Pain ratings, Conditioned pain modulation (CPM) response, Hormonal assessment
- Device · Behavioral · Biological
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 12 Years to 45 Years · Female only
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Migraine, Acute Treatment of Migraine
- Interventions
- Nerivio
- Device
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 244 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Musculoskeletal Pain, Neck Pain
- Interventions
- Pain Inducing Massage, Light Touch Massage, Coldpressor
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Low Back Pain
- Interventions
- Physical therapy
- Other
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Fort Sam Houston, Texas
- Conditions
- Chronic Pain
- Interventions
- Opioid Taper Pain perception
- Other
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Migraine
- Interventions
- Nerivio
- Device
- Lead sponsor
- Theranica
- Industry
- Eligibility
- 12 Years to 18 Years
- Enrollment
- 83 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Bridgewater, New Jersey
- Conditions
- Migraine
- Interventions
- Thermal stimuli, Pressure stimuli, Pain ratings, Pressure pain thresholds (PPT), Conditioned pain modulation (CPM) response, PedMIDAS (Pediatric Migraine Disability Assessment), Hormonal assessment, Pubertal status
- Device · Behavioral · Diagnostic Test + 1 more
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 11 Years to 15 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Healthy, Musculoskeletal Pain
- Interventions
- Pain Inducing Massage, Pain Free Massage, Coldpressor
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Healthy People
- Interventions
- Conditioned Pain Modulation (CPM)
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Pelvic Pain, Endometriosis
- Interventions
- Psychophysical assessment, Psychophysical assessments of experimental pain, Blood, urine and saliva samples, Biopsy and surgery-related data.
- Other · Behavioral · Diagnostic Test + 1 more
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 12 Years to 45 Years · Female only
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Healthy Adult
- Interventions
- Conditioned Pain Modulation (CPM)
- Behavioral
- Lead sponsor
- Priyanka Rana, PT, MPT, PhD
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- Shoulder Pain
- Interventions
- Quantitative Sensory Testing, Pain-Related Psychological Factors
- Other
- Lead sponsor
- University of Central Florida
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Orlando, Florida
- Conditions
- Headache, Migraine, Migraine, Migraine Disorders, Headache
- Interventions
- Cognitive Behavioral Therapy (CBT), Placebo, Amitriptyline, Biofeedback-Assisted Relaxation Training (BART), Cognitive Reappraisal Training (CR)
- Behavioral · Drug
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Other
- Eligibility
- 10 Years to 17 Years
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2025
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Anesthesia, Pain
- Interventions
- Dexmedetomidine, Propofol, Fentanyl, Peripheral Nerve Stimulation, Placebo
- Drug · Device
- Lead sponsor
- Keith M Vogt
- Other
- Eligibility
- 18 Years to 39 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania