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ClinicalTrials.gov public records Last synced Oct 22, 2026, 12:57 AM EDT

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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Confocal imaging Clear all
Enrolling by invitation No phase listed Observational

Shortwave Infrared Surgical Imaging Device Study

NCT07744425
View directory record Official record
Conditions
Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism, Sigmoid Colon Diverticulitis, Multinodular Goiter, Thyroid and Parathyroid Surgery
Interventions
Observational study of SWIR imaging device in surgery
Device
Lead sponsor
Cision Vision, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
6
States / cities
Palo Alto, California • Evanston, Illinois • Glenview, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Confocal Endomicroscopy of Pancreatic InVivo

NCT01035008
View directory record Official record
Conditions
Pancreatic Cysts
Interventions
Endoscopic Ultrasound (EUS)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 23, 2012 · Synced Oct 22, 2026, 12:57 AM EDT
Completed No phase listed Observational

Registry Trial to Determine pCLE Image Interpretation Criteria and Preliminary Accuracy for PSC Biliary Strictures

NCT02736708
View directory record Official record
Conditions
Primary Sclerosing Cholangitis
Interventions
probe based confocal laser endomicroscopy
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2020 · Synced Oct 22, 2026, 12:57 AM EDT
Completed No phase listed Observational

Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract

NCT01770405
View directory record Official record
Conditions
Pancreatic Cyst, Pancreatic Neoplasms, Pancreatic Adenoma, Pancreatic Cancer, Pancreatic Islet Cell Tumors, Lymph Node Mass, Lymphadenopathy, GIST
Interventions
Endoscopic ultrasound fine needle aspiration
Device
Lead sponsor
Mauna Kea Technologies
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
4
States / cities
Atlanta, Georgia • Manhasset, New York • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Oct 22, 2026, 12:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Confocal Probe-based Endoscopic Imaging, Colorectal Cancer, Gastrointestinal (GI) Pathologies

NCT00874263
View directory record Official record
Conditions
Colonic Polyps, Esophageal Diseases
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2012 · Synced Oct 22, 2026, 12:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma

NCT03699995
View directory record Official record
Conditions
Cutaneous Melanoma, Melanocytic Nevus, Skin Carcinoma
Interventions
Confocal Microscopy, Dermoscopy, Imaging Procedure, Lidocaine, Punch Biopsy, Shave Biopsy
Other · Procedure · Drug
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional

SLIT ABS: Study on Patients With Autoimmune Podocytopathy

NCT07516964
View directory record Official record
Conditions
Nephrotic Syndrome With Edema (Diagnosis), Minimal Change Nephrotic Syndrome, Focal Segmental Glomerulosclerosis (FSGS), Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy
Interventions
Serum and renal tissue analysis
Other
Lead sponsor
Meyer Children's Hospital IRCCS
Other
Eligibility
0 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2036
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Recruiting No phase listed Observational

Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

NCT02507141
View directory record Official record
Conditions
Head and Neck Cancer, Squamous Cell Carcinoma (SCC) of the Oral Cavity
Interventions
Reflectance Confocal Microscopy
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
5
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Harrison, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Imaging Human Skin With High-Speed Spectrally Encoded Confocal Microscopy

NCT04566302
View directory record Official record
Conditions
Pigmented Lesions, Pigmented Skin Lesion, Pigmented Moles, Skin Lesion
Interventions
SECM Skin Imaging
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 22, 2026, 12:57 AM EDT
Completed Phase 4 Interventional Results available

The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED

NCT02120079
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Lotemax, Soothe Tired Eyes Lubricant Eye Drop (Artificial Tears), In Vivo Confocal Microscopy (IVCM)
Drug · Diagnostic Test
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 22, 2026, 12:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Using Spectrally Encoded Confocal Microscopy (SECM) to Image the Esophagus

NCT02202590
View directory record Official record
Conditions
Eosinophilic Esophagitis
Interventions
SECM Capsule
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Completed No phase listed Observational

Sensitivity/Specificity Study of Non-invasive Imaging for Melanoma Diagnosis

NCT01556503
View directory record Official record
Conditions
Melanoma
Interventions
VivaScope System
Device
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
12 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Oct 22, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen

NCT07141121
View directory record Official record
Conditions
Prostate Cancer
Interventions
Histolog Scan
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Male only
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Withdrawn Not applicable Interventional

Confocal Fluorescence Microscopy of the Human Airways in Diagnostics of Lung Transplantation

NCT02395393
View directory record Official record
Conditions
Disorder Related to Lung Transplantation
Interventions
Alveoflex Confocal MiniprobeTM
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 22 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2021 · Synced Oct 22, 2026, 12:57 AM EDT
Terminated Early Phase 1 Interventional

A Feasibility Study of Confocal Microendoscopy in the Evaluation of Gastrointestinal Neoplasia -Project 1

NCT01384695
View directory record Official record
Conditions
GERD, Barrett's Esophagus
Interventions
Fluorescein, Proflavine hemisulfate
Drug
Lead sponsor
Anandasabapathy, Sharmila, M.D.
Individual
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2016 · Synced Oct 22, 2026, 12:57 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy

NCT00771355
View directory record Official record
Conditions
Vitiligo, Melasma, Hyperpigmentation, Hypopigmentation
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2011 · Synced Oct 22, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Investigation of MAIA Microperimeter Device: Mesopic Normative Database Collection

NCT06991127
View directory record Official record
Conditions
Healthy Eyes
Interventions
MAIA
Device
Lead sponsor
Centervue SpA
Industry
Eligibility
18 Years and older
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 22, 2026, 12:57 AM EDT
Completed Not applicable Interventional Results available

Using Spectrally Encoded Confocal Microscopy (SECM) to Visualise the Esophagus Using an SECM Probe

NCT02210039
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
SECM Probe
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Oct 22, 2026, 12:57 AM EDT
Active, not recruiting No phase listed Observational

A Study of Observation and Follow-up in People With Basal Cell Carcinoma

NCT05473507
View directory record Official record
Conditions
Basal Cell Carcinoma
Interventions
Digital Dermoscopy, Reflectance confocal microscopy (RCM), Optical coherence tomography (OCT), Dermtech tape-stripping, Total Skin Examinations
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Active, not recruiting Phase 2 Interventional

A Study on Radiation Therapy Guided by the Reflectance Confocal Microscopy (RCM)/Optical Coherence Tomography (OCT) Device in People With Basal Cell Carcinoma

NCT05294120
View directory record Official record
Conditions
Basal Cell Carcinoma
Interventions
Reflectance ConfocaL Microscopy And Optical Coherence Tomography Guided, Radiation Therapy
Device · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 22, 2026, 12:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ocular Surface Immune Response in Dry Eye Disease

NCT02042820
View directory record Official record
Conditions
Dry Eye Disease
Interventions
In vivo confocal microscopy (IVCM)
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Oct 22, 2026, 12:57 AM EDT
Not listed Phase 4 Interventional

Dupilmuab for Atopic Dermatitis Monitored With Noninvasive Imaging.

NCT05265234
View directory record Official record
Conditions
Eczema, Atopic Dermatitis
Interventions
Dupilumab, Optical Coherence Tomography, Reflectance confocal microscopy
Drug · Device
Lead sponsor
OptiSkin Medical
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 22, 2026, 12:57 AM EDT
Terminated No phase listed Observational

In Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions

NCT01993654
View directory record Official record
Conditions
Nevus, Racial Melanosis, Primary Acquired Melanosis, Conjunctival Malignant Melanoma
Interventions
HRT III with Non-Contact Cornea Rostock Module
Procedure
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
3
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 15, 2016 · Synced Oct 22, 2026, 12:57 AM EDT
Not listed No phase listed Observational

nCLE For Diagnosis Of Peripheral Lung Nodules By Robotic Navigational Bronchoscopy

NCT04441749
View directory record Official record
Conditions
Diagnosis of Peripheral Lung Nodules
Interventions
Images acquired by needle-based Confocal Laser Endomicroscopy (nCLE)
Device
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 22, 2026, 12:57 AM EDT