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ClinicalTrials.gov public records Last synced Oct 25, 2026, 10:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 294 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Contact Lens Wear Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Progression After Ceasing Myopia Control Contact Lens Wear

NCT01829230
View directory record Official record
Conditions
Myopia
Interventions
1 Day Acuvue Moist
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
9 Years to 13 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)

NCT01476722
View directory record Official record
Conditions
Healthy
Interventions
OPTI-FREE PureMoist multipurpose disinfecting solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2012 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of Kalifilcon A Daily Disposable Contact Lens

NCT04158466
View directory record Official record
Conditions
Contact Lens Wear
Interventions
Kalifilcon A Daily Disposable Contact Lenses, Biotrue ONEday Daily Disposable Contact Lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 55 Years
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
16
States / cities
Los Angeles, California • San Francisco, California • Torrance, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wear Experience With Daily Toric Contact Lenses Over a Long Day

NCT04844281
View directory record Official record
Conditions
Contact Lens, Astigmatism of Both Eyes
Interventions
Precision1® Daily Disposable Toric Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Wear Experience With a Daily Disposable Contact Lens

NCT04296877
View directory record Official record
Conditions
Contact Lens
Interventions
Daily Disposable Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Comparison Between Comfilcon A and Senofilcon C Lenses

NCT02920957
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A, senofilcon C
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
5
States / cities
Whittier, California • Ocoee, Florida • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses

NCT04529109
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A investigational cosmetic lens 1, etafilcon A investigational cosmetic lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 29 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Jacksonville, Florida • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2021 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Conjunctival Rebound After Scleral Lens Wear

NCT04340518
View directory record Official record
Conditions
Conjunctival Diseases
Interventions
Scleral lens
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2021 · Synced Oct 25, 2026, 10:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Precision of OCT and OCTA-based Ocular Measurements

NCT03859310
View directory record Official record
Conditions
Normal Eyes and Ocular Pathology
Interventions
SD-OCT
Device
Lead sponsor
Optovue
Industry
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Marysville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2019 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population

NCT04534517
View directory record Official record
Conditions
Visual Acuity
Interventions
JJV Investigational Multifocal Contact Lens, ACUVUE OASYS® with HYDRACLEAR® PLUS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
11
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Total30 For Contact Lens Dropouts

NCT06967298
View directory record Official record
Conditions
Dry Eye, Contact Lens Complication, Contact Lenses
Interventions
T30 Contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Approved Contact Lenses

NCT02759692
View directory record Official record
Conditions
Visual Acuity
Interventions
TEST Contact Lens, CONTROL Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
13
States / cities
Montgomery, Alabama • Jacksonville, Florida • Sarasota, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear

NCT01735045
View directory record Official record
Conditions
Myopia
Interventions
Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Device
Lead sponsor
Szabocsik and Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
5
States / cities
Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Dispensing Study for the Phenacite Project

NCT02436005
View directory record Official record
Conditions
Ametropia
Interventions
Phenacite, comfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens

NCT04422990
View directory record Official record
Conditions
Refractive Errors
Interventions
Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
14
States / cities
Los Angeles, California • Novato, California • Oakland, California + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2022 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wear Experience With Daily Contact Lenses Over a Long Day

NCT04535310
View directory record Official record
Conditions
Contact Lens
Interventions
Precision1® Daily Disposable Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Dispensing Evaluation of Printed Etafilcon A With Polyvinylpyrrolidone (PVP)

NCT01180777
View directory record Official record
Conditions
Myopia
Interventions
etafilcon A (A), etafilcon A (B), etafilcon A (C)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
6
States / cities
Cupertino, California • Los Angeles, California • San Jose, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Effect of an Investigational Multi-Purpose Solution on Lens Moisture

NCT01341990
View directory record Official record
Conditions
Contact Lens Moisture
Interventions
FID 114675A Multi-Purpose Disinfecting Solution (MPDS), ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS), Silicone Hydrogel Contact Lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Phase 2 Interventional

Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel

NCT03994406
View directory record Official record
Conditions
Contact Lens Discomfort, Contact Lens-induced Corneal Disorder, Contact Lens Acute Red Eye, Contact Lens-induced Corneal Fluorescein Staining
Interventions
CLM2 topical gel, Placebo topical gel
Drug
Lead sponsor
Glia, LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Clinical Comparison of Two Daily Disposable Contact Lenses

NCT04865354
View directory record Official record
Conditions
Refractive Errors
Interventions
Verofilcon A contact lenses, Somofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
8
States / cities
San Francisco, California • Maitland, Florida • Tallahassee, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2022 · Synced Oct 25, 2026, 10:42 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses

NCT01058629
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
SynergEyes A2 Hybrid Contact Lens
Device
Lead sponsor
SynergEyes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
10
States / cities
Campbell, California • Carlsbad, California • Encino, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Delefilcon A Contact Lenses

NCT06884202
View directory record Official record
Conditions
Refractive Errors, Myopia
Interventions
Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
16
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 25, 2026, 10:42 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot Clinical Evaluation of Approved Contact Lenses

NCT02540122
View directory record Official record
Conditions
Vision Disorders
Interventions
Marketed Contact Lens 1, Marketed Contact Lens 2, Marketed Contact Lens 3, Marketed Contact Lens 4
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 25, 2026, 10:42 AM EDT