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ClinicalTrials.gov public records Last synced Sep 26, 2026, 11:01 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Astigmatism
Interventions
senofilcon A toric contact lens, balafilcon A toric contact lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin

NCT02347631
Conditions
Soft Contact Lenses, Myopia
Interventions
Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 38 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treating Contact Lens Discomfort With Orthokeratology

NCT03566680
Conditions
Dry Eye, Contact Lens Complication
Interventions
Orthokeratology
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot Clinical Evaluation of Approved Contact Lenses

NCT02540122
Conditions
Vision Disorders
Interventions
Marketed Contact Lens 1, Marketed Contact Lens 2, Marketed Contact Lens 3, Marketed Contact Lens 4
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Conditions
Presbyopia
Interventions
Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
8
States / cities
Los Angeles, California • Oakland, California • Maitland, Florida + 5 more
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Assessment of Corneal Endothelial Function Following Hypoxic Stress

NCT04175938
Conditions
Fuchs' Endothelial Corneal Dystrophy
Interventions
Wearing of contact lens
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Myopia
Interventions
Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
7 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Mission Viejo, California • Oakland, California • San Francisco, California + 6 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses

NCT01309867
Conditions
Myopia
Interventions
Investigational Toric Lens, PureVision Toric Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Not yet recruiting Not applicable Interventional

Contact Lenses to Slow Myopia Progression in Adults

NCT07747311
Conditions
Myopia, Myopia Progression
Interventions
Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 30 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Berkeley, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Approved Contact Lenses

NCT02759692
Conditions
Visual Acuity
Interventions
TEST Contact Lens, CONTROL Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
13
States / cities
Montgomery, Alabama • Jacksonville, Florida • Sarasota, Florida + 10 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wear Experience With Daily Contact Lenses Over a Long Day

NCT04535310
Conditions
Contact Lens
Interventions
Precision1® Daily Disposable Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Approved Contact Lenses

NCT02699593
Conditions
Visual Acuity
Interventions
Test Contact Lens, Control Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
7
States / cities
Birmingham, Alabama • Jacksonville, Florida • Sarasota, Florida + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Toric Eye Strain and Stability Study

NCT01857102
Conditions
Astigmatism
Interventions
etafilcon A, etafilcon A for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Houston, Texas
Conditions
Myopia
Interventions
B&L RD2135-01 lens C, B&L RD2135-01 lens D, PureVision2, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Handling Comparison Between Two Contact Lens Types

NCT02310126
Conditions
Presbyopia
Interventions
etafilcon A (multi-focal), etafilcon A (sphere)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
8
States / cities
Jacksonville, Florida • Sarasota, Florida • Winter Park, Florida + 3 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Wavelength Intervention for Nearsighted Kids

NCT06598423
Conditions
Myopia
Interventions
Specialized soft contact lens 1, Specialized soft contact lens 2
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
7 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Hyperopia, Myopia
Interventions
somofilcon A lens, stenfilcon A lens, fanfilcon A lens, comfilcon A lens, verofilcon A lens, serafilcon A lens, lehfilcon A lens, delefilcon A lens, senofilcon A daily disposable lens, senofilcon A with blue light technology lens, senofilcon A bi-weekly lens, samfilcon A lens, kalilfilcon A lens
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Prototype Lenses With Experimental UV/HEV Blocker

NCT04885296
Conditions
Visual Acuity
Interventions
TRP-200, JJVC Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
12
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 9 more
Completed Not applicable Interventional Results available

Clinical Evaluation of Invigor Toric 1-Day Contact Lenses

NCT04016623
Conditions
Astigmatism
Interventions
1-day toric test contact lens, 1-day toric control contact lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
Myopia, Hyperopia
Interventions
Lens A (fanfilcon A), Lens B (lotrafilcon B)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Ocoee, Florida • State College, Pennsylvania
Conditions
Ametropia
Interventions
Lens A (comfilcon A lens), Lens B (lehfilcon A lens)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Ocoee, Florida • State College, Pennsylvania
Completed Not applicable Interventional Results available

Clinical Evaluation of an Investigational Soft Contact Lens

NCT01254747
Conditions
Myopia
Interventions
Delefilcon A contact lens, Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX), Nelfilcon A contact lens (DAILIES AquaComfort Plus), Narafilcon A contact lens (1-DAY ACUVUE TRUEYE)
Device
Lead sponsor
CIBA VISION
Industry
Eligibility
Not listed
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Duluth, Georgia
Completed Not applicable Interventional Results available

Assessment of Daily Disposable Silicone Hydrogel Lens Wear

NCT01093625
Conditions
Myopia
Interventions
Narafilcon B Contact Lens, Spectacles
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
15 Years to 39 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Columbus, Ohio