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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Contingency Management (CM) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Smoking Cessation Incentives Study

NCT04682067
View directory record Official record
Conditions
Smoking Cessation, Diabetes Type 2
Interventions
Contingency Management, Usual Care smoking cessation
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 4 Interventional Results available

Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users

NCT02445339
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Use Disorder
Interventions
XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 10, 2022 · Synced Sep 23, 2026, 12:24 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

NCT05897788
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Dependence With Current Use (Disorder)
Interventions
Text Message Check-ins, Contingency Management
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,808 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 23, 2026, 12:24 AM EDT
Recruiting Not applicable Interventional

PrEP Readiness Interventions for Sustained Motivation (PRISM)

NCT06637436
View directory record Official record
Conditions
HIV, Methamphetamine Disorders
Interventions
Motivational Interviewing (MI), Contingency Management (CM)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 2 Interventional

Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth

NCT01511380
View directory record Official record
Conditions
Substance Use, Sexual Risk Behaviors
Interventions
Risk Reduction Therapy for Adolescents, Usual services
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2016 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional Results available

Contingency Management for Smoking in Substance Abusers

NCT00807742
View directory record Official record
Conditions
Substance Abuse
Interventions
Nicotine Replacement Treatment (NRT), Brief Advice, Contingency Management, Non-Contingent Reinforcement
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 2 Interventional Results available

Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men

NCT00856323
View directory record Official record
Conditions
Amphetamine-Related Disorders, HIV, HIV Infections
Interventions
Truvada, CM
Drug · Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Voucher-Based Incentives in a Prevention Setting

NCT00607269
View directory record Official record
Conditions
Substance-related Disorders
Interventions
Voucher-Based Reinforcement Therapy
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2013 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional Results available

SMART Effectiveness Trial

NCT04464421
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Dependence, Treatment Adherence
Interventions
Contingency Management (CM), Brief Motivational Intervention + Substance Free Activities Session + Mindfulness-Based Adherence Promotion (BSM)
Behavioral
Lead sponsor
Karen Derefinko, PhD
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 23, 2026, 12:24 AM EDT
Recruiting Not applicable Interventional

The Less is More Study

NCT05153811
View directory record Official record
Conditions
Alcohol Use
Interventions
Counseling, mHealth
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
35 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Coral Gables, Florida • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Pharmacotherapy & CM for Opioid and Cocaine Dependence

NCT00838981
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Modafinil, Sugar Pill, Contingency Management, Methadone, cognitive behavioral treatment, Voucher Control
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Sep 23, 2026, 12:24 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers Results available

Understanding Effects of Cannabis Use and Abstinence on Neural Glutamate Homeostasis

NCT05664763
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
[18F]FPEB with PET, Cannabis abstinence
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Improving Antihypertensive Medication Adherence

NCT01296594
View directory record Official record
Conditions
High Blood Pressure, Substance Abuse
Interventions
Usual Care, Contingency Management
Other · Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Contingency Management for the Treatment of Co-Occurring Alcohol and Drug Misuse

NCT02222389
View directory record Official record
Conditions
Co-Occurring Alcohol and Drug Misuse
Interventions
CM for Alcohol, CM for drugs, CM for both substances, Non-Contingent group
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 4 Interventional Results available

A Smoking Cessation Intervention for Yale Dining Employees

NCT02562521
View directory record Official record
Conditions
Smoking Cessation
Interventions
Contingency management, Nicotine replacement therapy, Varenicline, Additional behavioral support
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2018 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users

NCT01334736
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Usual care, Lung age, Contingency Management, Lung age + Contingency Management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Contingency Management, Quitting Smoking, and ADHD

NCT02266784
View directory record Official record
Conditions
Cigarette Smoking, Smoking Cessation
Interventions
Contingency Management (CM), Transdermal nicotine skin patches (i.e. Habitrol), Supportive Counseling
Behavioral · Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Contingency Management for Adolescent Alcohol Abuse

NCT00595478
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Motivational Enhancement Therapy (MET)/CBT+CM, Motivational Enhancement Therapy (MET)/CBT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PrEP Readiness Interventions for Supporting Motivation

NCT04205487
View directory record Official record
Conditions
HIV Infections, Pre-exposure Prophylaxis, Substance Use Disorders
Interventions
Motivational Interviewing (MI), Contingency Management (CM)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older · Male only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2025 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 2 Interventional

Behavioral Treatment for Cocaine Dependent Women

NCT00914381
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Behavioral therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2002
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Phase 2 Interventional Results available

Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

NCT02896712
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Acceptance and Commitment Therapy (ACT), Drug Counseling (DC), Contingency Management (CM), Placebo, Modafinil
Behavioral · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional

SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence

NCT04080180
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Contingency Management, Brief Motivational Interviewing + Substance Free Activities + Mindfulness
Behavioral
Lead sponsor
Karen Derefinko, PhD
Other
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 23, 2026, 12:24 AM EDT
Completed Not applicable Interventional

Organizational Skills Training for Children With Attention Deficit Hyperactivity Disorder

NCT00381407
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Organizational Skills Training, Contingency management (CM)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
8 Years to 11 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
New York, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2013 · Synced Sep 23, 2026, 12:24 AM EDT
Not yet recruiting Not applicable Interventional

Reentry Incentives and Support for Engagement With Contingency Management

NCT07322588
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Reentry Incentives and Support for Engagement with Contingency Management (RISE-CM) Intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Warrenton, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 23, 2026, 12:24 AM EDT