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ClinicalTrials.gov public records Last synced Nov 11, 2026, 7:49 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 148 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Contingency Management for abstinence Clear all

Conditions: Cannabis Use
Interventions: Cannabis use abstinence for 11 weeks; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: E-Cig Use
Interventions: Remote Contingency Management (CM) for nicotine abstinence, Control; Behavioral · Other
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 20 Years
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Amphetamine-Related Disorders, HIV, HIV Infections
Interventions: Truvada, CM; Drug · Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 18 Years and older · Male only
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Opioid-use Disorder
Interventions: Contingency Management for adherence, Contingency Management for abstinence; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 375 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Use, Drug Use, Risk Behavior, Sexual Behavior
Interventions: Contingency management, Employment Only; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Abuse, Alcohol Dependence, Heavy Drinking Days
Interventions: Kudzu extract, Placebo, Medical Management; Drug · Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: 21 Years to 60 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Alcohol Use Disorder
Interventions: Phosphatidylethanol-based Contingency Management, Non-Contingent Control; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Cocaine Use Disorder
Interventions: Prize-Based Contingency Management, Treatment As Usual Outpatient Substance Use Treatment; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Co-Occurring Alcohol and Drug Misuse
Interventions: CM for Alcohol, CM for drugs, CM for both substances, Non-Contingent group; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Cigarette Smoking
Interventions: Contingency Management, Brief smoking cessation counseling; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Efficacy of Financial Incentives
Interventions: Voucher-based incentives; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 166 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Substance-Related Disorders
Interventions: Functional Family Therapy, Motivational Enhancement Tx/Cognitive Behavioral Tx, Contingency Management; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 17 Years
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Opiate-Related Disorders, Cocaine-Related Disorders
Interventions: Methadone, Contingency Management, Methadone dose, Contingency Management/Noncontingent Incentives; Drug · Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Smoking Cessation, Alcohol Drinking
Interventions: Nicotine Replacement Therapy, Bupropion, Cognitive Behavioral Treatment, Mobile Contingency Management, Mobile Monitoring; Other · Drug · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tobacco Use Disorder
Interventions: Smartphone-based Financial Incentives, Best Practices; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Neonatal Opiate Withdrawal Syndrome
Interventions: Finnegan Neonatal Abstinence Scoring Tool, Eat, Sleep, Console (ESC) care tool; Other
Lead sponsor: Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program; Network
Eligibility: Up to 3 Days
Enrollment: 1,305 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 26
States / cities: Newark, Delaware • Tampa, Florida • Honolulu, Hawaii + 21 more

Conditions: Alcohol Drinking, Veterans
Interventions: Cognitive Behavioral Therapy (CBT), Mobile Contingency Management (mCM), Long-term incentive; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking, Stress Disorders, Post-Traumatic
Interventions: Smoking Cessation Cognitive Behavioral Therapy (CBT), Bupropion, Cognitive Processing Therapy, Smoking Abstinence Reinforcement Therapy, Yoked Contingency Management; Behavioral · Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Alcohol Use Disorder, Contingency Management
Interventions: Standard care, Contingency management; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Schizophrenia, Bipolar Disorder, Major Depressive Disorder, Alcohol Dependence
Interventions: Usual CM, High-Magnitude CM, Shaping CM; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 392 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Seattle, Washington • Spokane, Washington

Conditions: Alcohol Use
Interventions: contingency management for abstinence; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Tobacco Use Disorder
Interventions: Varenicline, Contingency Management, Counseling; Drug · Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 40 Years
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 3
States / cities: Charleston, South Carolina • Florence, South Carolina • Pickens, South Carolina

Conditions: Neonatal Abstinence Syndrome, Neonatal Withdrawal Syndrome
Interventions: Buprenorphine, Morphine Sulfate; Drug
Lead sponsor: Pediatrix; Other
Eligibility: Up to 1 Year
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Tobacco Use Cessation
Interventions: Nicotine patch, nicotine gum, nicotine nasal spray, nicotine inhaler, Varenicline or bupropion, Contingency Management; Drug · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 4
States / cities: Bridgeport, Connecticut • New Haven, Connecticut • Brooklyn, New York + 1 more

Search by objective public record fields.

Cannabis Use and Epigenetic Alterations in Human Male Sperm Cells

Quit Nicotine: E-Cig Cessation Intervention

Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men

Contingency Management to Enhance Office-Based Buprenorphine Treatment

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1

Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons

Phosphatidylethanol-Based Contingency Management for Housing

Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project

Contingency Management for the Treatment of Co-Occurring Alcohol and Drug Misuse

Contingency Management for Smoking in Substance Abusers

Voucher Based Incentives to Treat Pregnant Smokers

Family and Adolescent Motivational Incentives for Leveraging Youth

Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management

Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

Smartphone-based Financial Incentives

Eating, Sleeping, Consoling for Neonatal Withdrawal (ESC-NOW): a Function-Based Assessment and Management Approach

Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder

CPT-SMART for Treatment of PTSD and Cigarette Smoking

Dual Reinforcement Contingency Management for Alcohol Use Disorders

Individualizing Incentives for Alcohol in the Severely Mentally Ill

Remote Monitoring and Contingency Management Reinforcement for Alcohol Abstinence

Cannabis and Tobacco Co-use Study

Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS)

A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV