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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Continuous Epidural Analgesia Clear all
Completed No phase listed Observational

Chloroprocaine for Continuous Epidural Analgesia in Neonates and Infants

NCT02207855
View directory record Official record
Conditions
Anesthesia
Interventions
Chloroprocaine
Drug
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 2 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 28, 2016 · Synced Sep 20, 2026, 8:53 PM EDT
Recruiting Phase 2Phase 3 Interventional

IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

NCT06559969
View directory record Official record
Conditions
Laparotomy
Interventions
Intravenous administered opioid, Epidural administered opioid
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Comparison Between Epidural and Bilateral Paravertebral Blocks in Liver Resection

NCT01407666
View directory record Official record
Conditions
Liver Disease, Pain
Interventions
paravertebral blocks
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Sep 20, 2026, 8:53 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome

NCT02094352
View directory record Official record
Conditions
Complex Regional Pain Syndrome
Interventions
Ketamine Infusion + Epidural Infusion, Control Group + Epidural infusion, Ketamine Booster Infusion, Control Group Booster Infusion
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 30, 2018 · Synced Sep 20, 2026, 8:53 PM EDT
Not yet recruiting Phase 4 Interventional

A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device

NCT06729255
View directory record Official record
Conditions
Postdural Puncture Headache, Epidural Analgesia, Obstetric
Interventions
EpiZact-assisted epidural placement
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
15 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Phase 4 Interventional Results available

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

NCT01846221
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine, Fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Sep 20, 2026, 8:53 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Does Ultrasound Help Junior Anesthesia Residents With Placement of Labor Analgesia in Pregnant Patients

NCT02747238
View directory record Official record
Conditions
Pregnancy
Interventions
Ultrasound, No ultrasound, Epidural infusion
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 20, 2026, 8:53 PM EDT
Completed No phase listed Observational

Detection of Postoperative Respiratory Depression in High Risk Patients Utilizing Minute Ventilation Monitoring

NCT04017702
View directory record Official record
Conditions
Respiratory Depression
Interventions
Expiron respirator
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 80 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Sep 20, 2026, 8:53 PM EDT
Completed No phase listed Observational

Nuss Procedure: Clinical Options in Pediatric Pain Management?

NCT02009267
View directory record Official record
Conditions
Pectus Excavatum
Interventions
Patient controlled analgesia, Continuous thoracic epidural infusions, Continuous paravertebral blockade
Device · Procedure
Lead sponsor
Ralph Beltran
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Sep 20, 2026, 8:53 PM EDT
Recruiting Phase 2 Interventional

Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

NCT06411795
View directory record Official record
Conditions
Duodenal Neoplasm, Pancreatic Neoplasm
Interventions
Bupivacaine, Hydromorphone, Iopamidol, Liposomal Bupivacaine, Medical Chart Review, Questionnaire Administration, Thoracic Epidural Analgesia, Ultrasound Imaging, X-Ray Imaging
Drug · Other · Procedure
Lead sponsor
Masonic Cancer Center, University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Not applicable Interventional Results available

Pain Management for Pectus Excavatum Repair

NCT00413582
View directory record Official record
Conditions
Postoperative Pain
Interventions
Epidural Analgesia, Patient-Controlled IV Analgesia
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
8 Years to 18 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 15, 2012 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension

NCT05906368
View directory record Official record
Conditions
Anesthesia, Epidural, Hypotension
Interventions
ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
Diagnostic Test
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Not applicable Interventional

Pain Relief Effects on Length of Labor

NCT01750099
View directory record Official record
Conditions
Labor Pain
Interventions
Combined Spinal-epidural, Continuous Lumbar epidural
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years to 44 Years · Female only
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2014 · Synced Sep 20, 2026, 8:53 PM EDT
Terminated Phase 4 Interventional Results available

Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

NCT03115151
View directory record Official record
Conditions
Pain
Interventions
Bupivacaine, Hydromorphone, Fentanyl
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Not applicable Interventional Results available

Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery

NCT01552226
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer, Colonic Diverticulosis
Interventions
Continuous Preperitoneal Analgesia, Continuous Epidural Analgesia
Device
Lead sponsor
Trinity Health Michigan
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 20, 2026, 8:53 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Patient Controlled Epidural Analgesia Versus Continuous Epidural Infusion: Obstetrical and Neonatal Outcomes

NCT00810914
View directory record Official record
Conditions
Pain
Interventions
bupivicaine epidural, bupivicaine epidural infusion patient epidural, bupivicaine
Drug
Lead sponsor
MemorialCare
Other
Eligibility
18 Years and older · Female only
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2009 · Synced Sep 20, 2026, 8:53 PM EDT
Not yet recruiting Phase 3 Interventional

An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service

NCT07296770
View directory record Official record
Conditions
Postsurgical Pain Management, Postsurgical Pain, Chronic, Opioid Use After Surgery
Interventions
TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures, Psychological Management and Pain Education, Physical Therapy
Device · Drug · Procedure + 1 more
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 20, 2026, 8:53 PM EDT
Completed Not applicable Interventional Results available

Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters

NCT02678039
View directory record Official record
Conditions
Pain, Postoperative, Pain, Chronic
Interventions
Fluoroscopy, Traditional
Device · Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Sep 20, 2026, 8:53 PM EDT
Terminated Not applicable Interventional Results available

Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy

NCT02164929
View directory record Official record
Conditions
Laparoscopic Colorectal Resection
Interventions
TAP block, Epidural, Paravertebral block, Acetaminophen 1g IV, Dexamethasone 4mg, Midazolam up to 2mg, Propofol 1-2.5 mg/kg, Sevoflurane to keep a bispectral index of between 40-60, Local infiltration with 10 mL of plain ropivacaine 0.25%, Lidocaine, Epinephrine, Hydromorphone
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 20, 2026, 8:53 PM EDT
Active, not recruiting Phase 3 Interventional

Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection

NCT02523443
View directory record Official record
Conditions
Liver Cancer, Pain Management
Interventions
IV PCA, PCEA
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
3
States / cities
Basking Ridge, New Jersey • Commack, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 20, 2026, 8:53 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section

NCT01362998
View directory record Official record
Conditions
Pain
Interventions
Preservative free morphine, Fentanyl
Drug
Lead sponsor
Goodman, Evan, M.D.
Individual
Eligibility
18 Years to 50 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 20, 2026, 8:53 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Association Between Fluid Administration, Oxytocin Administration, and Fetal Heart Rate Changes

NCT02121184
View directory record Official record
Conditions
Pregnancy, Labor Pain
Interventions
Routine oxytocin, Half-dose oxytocin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 20, 2026, 8:53 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Loading: High Volume, Low Concentration

NCT02803450
View directory record Official record
Conditions
Labor and Delivery
Interventions
Epidural needle, Catheter Administration, Standard of Care Epidural Administration
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 89 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Sep 20, 2026, 8:53 PM EDT
Withdrawn Phase 4 Interventional

Epidural Fentanyl-bupivacaine Versus Clonidine-bupivacaine for Breakthrough Pain in Advanced Labor

NCT00691795
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine or fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Sep 20, 2026, 8:53 PM EDT