Independent directory Public ClinicalTrials.gov records United States
Clear filters
ClinicalTrials.gov public records Last synced Sep 11, 2026, 10:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 325 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Preterm Neonates
Interventions
Gradual weaning from Nasal CPAP in preterm neonates
Procedure
Lead sponsor
Maimonides Medical Center
Other
Eligibility
24 Weeks to 32 Weeks
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Conditions
Prediction of Extubation Readiness
Interventions
Cardiorespiratory signal acquisition
Other
Lead sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Other
Eligibility
Not listed
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Detroit, Michigan • Providence, Rhode Island
Conditions
Acute Respiratory Distress Syndrome
Interventions
Recruitment Maneuver with PEEP and Tidal Volume Optimization
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Gynecologic Cancer, Genitourinary Cancer
Interventions
Airway Pressure Release Ventilation, Conventional Mechanical Ventilation
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Results available

Mild Cognitive Impairment and Obstructive Sleep Apnea

NCT01482351
Conditions
Obstructive Sleep Apnea, Mild Cognitive Impairment
Interventions
CPAP adherence intervention, Attention control intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
55 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Abington, Pennsylvania • Philadelphia, Pennsylvania • Fairfax, Virginia
Conditions
Chronic Obstructive Airway Disease
Interventions
Bi-level positive airway pressure (BPAP), Oxygen, CPAP
Device · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Interstitial Lung Disease, Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure (CPAP) therapy, Nox A1 Recorder
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
2,021 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Conditions
Acute Lung Injury, Adult Respiratory Distress Syndrome
Interventions
Low-tidal-volume ventilation, Airway Pressure Release Ventilation (APRV)
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy

NCT02755831
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Pre-natal care
Device · Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older · Female only
Enrollment
193 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Conditions
Obstructive Sleep Apnea
Interventions
Drug-induced sleep endoscopy (DISE), High-resolution manometry (HRM):
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
5 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Study of Nasal Airflow Pressure Optimization to Resolve Excessive Snoring

NCT01949584
Conditions
Snoring
Interventions
nasal continuous positive airway pressure less than or equal to 6 cm H2O
Device
Lead sponsor
inSleep Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Atlanta, Georgia • Baltimore, Maryland • Lanham, Maryland
Withdrawn Not applicable Interventional Accepts healthy volunteers

Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy

NCT04013399
Conditions
Obstructive Sleep Apnea, Pregnancy Related, Insulin Sensitivity
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Barnes-Jewish Hospital
Other
Eligibility
20 Years to 39 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Transient Tachypnea of the Newborn
Interventions
High Flow Nasal Cannula, Bubble Nasal CPAP
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 24 Hours
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

CPAP vs ASV for Insomnia

NCT02365064
Conditions
Insomnia, Sleep-Disordered Breathing
Interventions
AirCurve 10 ASV
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Albuquerque, New Mexico
Completed Not applicable Interventional Results available

Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events

NCT03183063
Conditions
Pulmonary Thromboembolisms, Pulmonary Embolism
Interventions
4DCT and SPECT/CT, 4DCT with BiPAP and SPECT/CT, 4DCT with CTA in suspected PE
Device
Lead sponsor
Thomas Guerrero
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Royal Oak, Michigan
Conditions
COVID-19, Sleep Apnea
Interventions
Continuous positive airway pressure
Device
Lead sponsor
Venkatesh Krishnamurthy
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
COVID-19, Oscillation and Lung Expansion
Interventions
MetaNeb® System
Device
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia • Evanston, Illinois
Conditions
Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions
Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm
Drug · Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
16 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Severe Acute Respiratory Syndrome Coronavirus 2, Hypoxemic Respiratory Failure, Pneumonia, Viral, COVID
Interventions
Helmet Continuous Positive Airway Pressure (CPAP), High Flow Nasal Oxygen (HFNO)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Terminated Not applicable Interventional Results available

Early CPAP in COVID-19 Confirmed or Suspected Patients

NCT04390191
Conditions
COVID-19, COVID, Coronavirus
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Diabetes Mellitus Type 2
Interventions
Positive Airway Pressure therapy, Lifestyle counseling
Device · Behavioral
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
11
States / cities
Mission Viejo, California • Temecula, California • Coral Gables, Florida + 8 more
Completed No phase listed Observational Results available

Third International Study on Mechanical Ventilation

NCT01093482
Conditions
Acute Respiratory Failure
Interventions
Not listed
Lead sponsor
Hospital Universitario Getafe
Other
Eligibility
18 Years and older
Enrollment
8,151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
18
States / cities
Iowa City, Iowa • Louisville, Kentucky • Boston, Massachusetts + 12 more
Conditions
Hypoxemia
Interventions
SuperNO2VA Et Nasal Positive Pressure Mask, Supplemental Oxygen Face Mask
Device
Lead sponsor
Vyaire Medical
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome

NCT03985657
Conditions
Sleep-disordered Breathing, Snoring
Interventions
CPAP
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland