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ClinicalTrials.gov public records Last synced Oct 5, 2026, 6:26 AM EDT

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Showing 73–96 of 304 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Continuous Positive Airway Pressure (CPAP) Clear all
Completed Not applicable Interventional Results available

Effect of CPAP on Postoperative Delirium

NCT01816685
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Delirium
Interventions
CPAP
Device
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2015 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional

Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery

NCT01697878
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
CPAP followed by atmospheric pressure, Atmospheric pressure followed by CPAP
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex Steroids, Sleep, and Metabolic Dysfunction in Women

NCT00805207
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS), Obstructive Sleep Apnea, Obesity
Interventions
Progesterone, testosterone, glucocorticoid, continuous positive airway pressure, Estrogen, Control
Drug · Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea

NCT00607893
View directory record Official record
Conditions
Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
Interventions
Continuous Positive Airway Pressure (CPAP), Sham CPAP
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
20 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 5, 2026, 6:26 AM EDT
Terminated Not applicable Interventional Results available

Early CPAP in COVID-19 Confirmed or Suspected Patients

NCT04390191
View directory record Official record
Conditions
COVID-19, COVID, Coronavirus
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Results available

Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment

NCT00252629
View directory record Official record
Conditions
Apnea, Sleep, Chronic Fatigue Syndrome
Interventions
Nasal CPAP treatment during sleep
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
32 Years to 52 Years · Male only
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2014 · Synced Oct 5, 2026, 6:26 AM EDT
Recruiting Not applicable Interventional

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

NCT03422302
View directory record Official record
Conditions
Lung Carcinoma, Malignant Respiratory Tract Neoplasm, Metastatic Malignant Neoplasm in the Lung
Interventions
Biphasic Positive Airway Pressure, Computed Tomography, Continuous Positive Airway Pressure, Deep Inspiration Breath Hold, Radiation Therapy Treatment Planning and Simulation, Stereotactic Body Radiation Therapy
Device · Procedure · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 5, 2026, 6:26 AM EDT
Withdrawn No phase listed Observational

Using CPAP to Improve Menstruation in Women With Polycystic Ovarian Syndrome and Obstructive Sleep Apnea

NCT03155828
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Anovulation, Polycystic Ovarian Syndrome
Interventions
CPAP
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 35 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 5, 2026, 6:26 AM EDT
Not yet recruiting No phase listed Observational

Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

NCT06023927
View directory record Official record
Conditions
Normal Tension Glaucoma, Obstructive Sleep Apnea
Interventions
Clinical observation, diagnostic testing
Other
Lead sponsor
Northwell Health
Other
Eligibility
21 Years and older
Enrollment
100 participants
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Early Phase 1 Interventional

Promoting Continuous Positive Airway Pressure (CPAP) Adherence

NCT01335854
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Web-based Access to CPAP Data, Web-based Access to CPAP Data with Financial Incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Wynnewood, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Results available

Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea

NCT01196117
View directory record Official record
Conditions
Sleep Apnea, Sleep Disordered Breathing
Interventions
14 days of placebo therapy, 14 days of CPAP therapy
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Oct 5, 2026, 6:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness

NCT00393913
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2016 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Phase 2 Interventional

Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack

NCT00251290
View directory record Official record
Conditions
Transient Ischemic Attack, Sleep Apnea
Interventions
auto-titrating continuous positive airway pressure
Procedure
Lead sponsor
Yale University
Other
Eligibility
45 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 3, 2009 · Synced Oct 5, 2026, 6:26 AM EDT
Terminated Phase 3 Interventional

Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants

NCT00005774
View directory record Official record
Conditions
Infant, Newborn, Respiratory Distress Syndrome, Respiratory Insufficiency
Interventions
Early surfactant, Standard practice
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 12 Hours
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
13
States / cities
Birmingham, Alabama • Palo Alto, California • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy

NCT03369197
View directory record Official record
Conditions
Hypoxia, Endoscopy, Anesthesia Morbidity
Interventions
Nasal Mask, Control: Nasal Cannula
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Phase 2 Interventional

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

NCT05951023
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Eszopiclone 2 mg, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 5, 2026, 6:26 AM EDT
Terminated Not applicable Interventional

Study of Room Air Versus 60% Oxygen for Resuscitation of Premature Infants

NCT01773746
View directory record Official record
Conditions
Extreme Prematurity - Less Than 28 Weeks
Interventions
Neonatal Resuscitation
Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
6
States / cities
San Diego, California • Farmington, Connecticut • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 5, 2026, 6:26 AM EDT
Recruiting No phase listed Observational

Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea

NCT04712656
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
CPAP therapy
Device
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 75 Years
Enrollment
1,739 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 5, 2026, 6:26 AM EDT
Terminated Not applicable Interventional

Extubation Readiness Study in Very Low Birthweight Infants

NCT01471431
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
spontaneous breathing trial
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
48 Hours to 14 Weeks
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2016 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Results available

TPAP for Comfort in OSA

NCT06264128
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
TPAP, CPAP
Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B

NCT01738009
View directory record Official record
Conditions
Sleep Apnea
Interventions
Induction of flow limitation
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Utility of Continuous Positive Airway Pressure in the Treatment of High Altitude Pulmonary Edema

NCT04186598
View directory record Official record
Conditions
Continuous Positive Airway Pressure, High Altitude Pulmonary Edema
Interventions
CPAP mask system, Nifedipine 30 MG, CPAP mask system without PEEP
Device · Drug
Lead sponsor
CommonSpirit Health
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Breckenridge, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 5, 2026, 6:26 AM EDT
Recruiting Not applicable Interventional

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

NCT05156112
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
Interventions
Positive Airway Pressure Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 5, 2026, 6:26 AM EDT
Completed Phase 2 Interventional Results available

The Sleep, Liver Evaluation and Effective Pressure Study

NCT01482065
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Interventions
CPAP (ResMed S9 autoset CPAP)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Oct 5, 2026, 6:26 AM EDT