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ClinicalTrials.gov public records Last synced Oct 12, 2026, 11:49 AM EDT

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Showing 97–120 of 236 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Continuous Positive Airway Pressure (CPAP) Treatment Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Brain Sleep Clearance of Amyloid-Beta Peptides

NCT02474251
View directory record Official record
Conditions
Obstructive Sleep Apnea, Alzheimer's Disease
Interventions
Continuous positive airway pressure device
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
30 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2020 · Synced Oct 12, 2026, 11:49 AM EDT
Withdrawn Phase 3 Interventional

Safety Study of Positive Airway Pressure Via a Nasal Mask in Obese Patients

NCT01627925
View directory record Official record
Conditions
Upper Airway Obstruction
Interventions
nasal mask and continuous positive airway pressure
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Phase 2 Interventional

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

NCT05951023
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Eszopiclone 2 mg, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional Results available

Stroke and CPAP Outcome Study 3

NCT06029959
View directory record Official record
Conditions
Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, Motivation
Interventions
Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET), Mobile Health intervention
Device · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Impact of Continuous Positive Airway Pressure on Breathing Motion Amplitude

NCT02852473
View directory record Official record
Conditions
Cancer
Interventions
Continuous Positive Airway Pressure
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 14, 2016 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional Results available

NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy

NCT02107300
View directory record Official record
Conditions
Xerostomia
Interventions
NeutraSal, Placebo Comparator
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 84 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Oct 12, 2026, 11:49 AM EDT
Recruiting No phase listed Observational

Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics

NCT05429983
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2022 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional

Impact of Automated Education and Follow-up Mechanisms on Patient Engagement

NCT02279901
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Telemedicine Education, IVR
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,873 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Phase 2 Interventional

Do Endotypes Predict Response and Sequelae in OSA Patients

NCT04875364
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Sleep Apnea, Obstructive, Sleep, Sleep Disorder
Interventions
Eszopiclone, Supplemental Oxygen, Continuous Positive Airway Pressure (CPAP)
Drug · Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Phase 2 Interventional Results available

Dimethyl Fumarate for Obstructive Sleep Apnea

NCT02438137
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA, Sleep Apnea
Interventions
Dimethyl fumarate, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Early Phase 1 Interventional

3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea

NCT02261857
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Craniofacial Abnormalities, Pediatric Disorder
Interventions
Personalized continuous positive airway pressure (CPAP) mask
Device
Lead sponsor
Glenn Green
Other
Eligibility
1 Year to 18 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 12, 2026, 11:49 AM EDT
Withdrawn No phase listed Observational

Using CPAP to Improve Menstruation in Women With Polycystic Ovarian Syndrome and Obstructive Sleep Apnea

NCT03155828
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Anovulation, Polycystic Ovarian Syndrome
Interventions
CPAP
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 35 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 12, 2026, 11:49 AM EDT
Terminated Not applicable Interventional

Acute Lung Injury Ventilator Evaluation (ALIVE)

NCT01901354
View directory record Official record
Conditions
Acute Lung Injury, Adult Respiratory Distress Syndrome
Interventions
Low-tidal-volume ventilation, Airway Pressure Release Ventilation (APRV)
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 28, 2017 · Synced Oct 12, 2026, 11:49 AM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 12, 2026, 11:49 AM EDT
Terminated Not applicable Interventional Results available

Obstructive Sleep Apnea Treatment to Improve Cardiac Rehabilitation

NCT02005445
View directory record Official record
Conditions
Obstructive Sleep Apnea, Coronary Heart Disease
Interventions
CPAP, HLSE
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 12, 2026, 11:49 AM EDT
Terminated Not applicable Interventional

Neotech RAM Cannula Versus Conventional Binasal Prong Continuous Positive Airway Pressure (CPAP) to Treat Respiratory Distress in Low Birth Weight Neonates

NCT02168257
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn, Continuous Positive Airway Pressure, Low Birth Weight Infants
Interventions
RAM Cannula, Binasal Prong CPAP
Device
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 12, 2026, 11:49 AM EDT
Completed No phase listed Observational

The Effect of Nasal Continuous Positive Airway Pressure Treatment on PTSD Symptoms.

NCT01512771
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Anxiety, Nightmares, Unrefreshed Sleep
Interventions
CPAP
Other
Lead sponsor
Northport Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Northport, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Oct 12, 2026, 11:49 AM EDT
Recruiting Not applicable Interventional

OurSleepKit To Support CPAP Adherence

NCT06621511
View directory record Official record
Conditions
Obstructive Sleep Apnea, CPAP Treatment, Treatment Adherence
Interventions
OurSleepKit
Behavioral
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional Results available

Effective Treatment of Sleep Apnea in Prediabetes to Reduce Cardiometabolic Risk

NCT01156116
View directory record Official record
Conditions
Diabetes, Sleep Apnea
Interventions
CPAP mask, Placebo
Device · Drug
Lead sponsor
University of Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers

NCT05512585
View directory record Official record
Conditions
Healthy
Interventions
awake prone positioning with advanced respiratory support (high-flow nasal cannula or continuous positive airway pressure)
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 9, 2022 · Synced Oct 12, 2026, 11:49 AM EDT
Terminated Not applicable Interventional Results available

Diabetes-Obstructive Sleep Apnea Treatment Trial

NCT01901055
View directory record Official record
Conditions
Type 2 Diabetes, Obstructive Sleep Apnea
Interventions
CPAP, Sham-CPAP, Diabetes Education
Device · Behavioral
Lead sponsor
Eileen R. Chasens
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Detroit, Michigan • Pittsburgh, Pennsylvania • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Phase 1 Interventional Results available

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

NCT05094271
View directory record Official record
Conditions
OSA, Sleep Apnea, Obstructive Sleep Apnea, Alzheimer Disease
Interventions
Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air
Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years to 85 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea

NCT00607893
View directory record Official record
Conditions
Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
Interventions
Continuous Positive Airway Pressure (CPAP), Sham CPAP
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
20 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 12, 2026, 11:49 AM EDT
Completed Not applicable Interventional Results available

Long QT Syndrome and Sleep Apnea

NCT03678311
View directory record Official record
Conditions
Long QT Syndrome, Sleep Apnea
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 12, 2026, 11:49 AM EDT