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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Continuous Positive Airway Pressure Machine Clear all
Completed Phase 3 Interventional

Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure

NCT00665977
View directory record Official record
Conditions
Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions
Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm
Drug · Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
16 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 6, 2010 · Synced Sep 5, 2026, 11:40 AM EDT
Recruiting Phase 1 Interventional

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

NCT03860233
View directory record Official record
Conditions
Sleep Apnea, Sleep Apnea, Obstructive
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Vivek Jain
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

CPAP to Treat Cognitive Dysfunction in MS

NCT02544373
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
PAP therapy
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Sep 5, 2026, 11:40 AM EDT
Completed No phase listed Observational

Face of Sleepiness

NCT01060436
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP or BiPAP machines
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 5, 2016 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Phase 3 Interventional Results available

Apnea Positive Pressure Long-Term Efficacy Study

NCT00051363
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Sleep
Interventions
Active CPAP, Sham CPAP
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
5
States / cities
Tucson, Arizona • Palo Alto, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 27, 2018 · Synced Sep 5, 2026, 11:40 AM EDT
Withdrawn Not applicable Interventional

Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations

NCT01497691
View directory record Official record
Conditions
Asthma
Interventions
NIPPV (PALMtop PTV), Volumetric CO2 (NM3), USCOM
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
2 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 5, 2026, 11:40 AM EDT
Terminated Not applicable Interventional

BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial

NCT05848115
View directory record Official record
Conditions
Asthma in Children
Interventions
Bi-level Positive Airway Pressure, Sham Bi-level Positive Airway Pressure
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 17 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional

Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women

NCT04993651
View directory record Official record
Conditions
Morbid Obesity, Cesarean Delivery Affecting Fetus
Interventions
CPAP
Device
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Comparing Auto-adjustable Positive Airway Pressure to Continuous Positive Airway Pressure in Children With Sleep Apnea

NCT01846988
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
crossover treatment (REMstar Auto A-Flex)
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 20 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional

Effect of CPAP (Continuous Positive Airway Pressure) on Lung Function in Asthmatics With Sleep Apnea

NCT00238069
View directory record Official record
Conditions
Asthma, Sleep Apnea
Interventions
CPAP machine as a result of sleep study
Device
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Stroke and CPAP Outcome Study 2

NCT02809430
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Stroke, Patient Adherence
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Sep 5, 2026, 11:40 AM EDT
Withdrawn Not applicable Interventional

Effect of Treating Sleep Disorder Breathing in Patients With Resistant Hypertension

NCT00973531
View directory record Official record
Conditions
Sleep Apnea, Hypertension
Interventions
Autotitrating Positive Airway Pressure (APAP), Traditional Split Titration Polysomnogram
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)

NCT01797705
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
DeVilbiss AutoAdjust CPAP with revised algorithm
Device
Lead sponsor
DeVilbiss Healthcare LLC
Industry
Eligibility
21 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

NCT01808508
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea Syndrome
Interventions
Continuous positive airway pressure, Sham or placebo continuous positive airway pressure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 20 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Sep 5, 2026, 11:40 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Evaluating Changes in Middle Ear Pressure Caused by CPAP

NCT02882022
View directory record Official record
Conditions
Eustachian Tube Disorder
Interventions
Continuous positive airway pressure
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 5, 2026, 11:40 AM EDT
Terminated Not applicable Interventional

Determination of Upper Airway Collapsibility During Routine CPAP Titration

NCT02566278
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway collapsibility (Pcrit)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Modulation Of Airway Reactivity With Chronic Mechanical Strain

NCT02396849
View directory record Official record
Conditions
Asthma
Interventions
Continuous Positive Airway Pressure (CPAP), Continuous Positive Airway Pressure (CPAP) Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
8 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Sep 5, 2026, 11:40 AM EDT
Withdrawn Not applicable Interventional

NiPPV in the Treatment of Acute Asthma Exacerbations

NCT03219736
View directory record Official record
Conditions
Bronchial Asthma, Status Asthmaticus
Interventions
Standard of Care therapies, NiPPV Therapy, Routine Respiratory Care
Procedure · Device
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
2 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 5, 2026, 11:40 AM EDT
Withdrawn Not applicable Interventional

Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center

NCT05754255
View directory record Official record
Conditions
Colonoscopy, Positive-Pressure Respiration
Interventions
Nasal Cannula, Nasal Positive Airway Pressure System
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Results available

Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism

NCT01503164
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Sleep-disordered Breathing
Interventions
Positive Pressure Therapy (PAP), LifeStyle Counseling
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Phase 1 Interventional Results available

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

NCT05094271
View directory record Official record
Conditions
OSA, Sleep Apnea, Obstructive Sleep Apnea, Alzheimer Disease
Interventions
Supplemental Oxygen, Continuous Positive Airway Pressure Machine, Room Air
Other · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years to 85 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional

Telemedici ne Management of Veterans With Newly Diagnosed Obstructiv e Sleep Apnea (OSA)

NCT02159885
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Telemonitoring
Other
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
18 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Sleep Apnea on Risk of Atrial Fibrillation

NCT02576587
View directory record Official record
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Continuous Positive Airway Pressure
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 5, 2026, 11:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD

NCT02641496
View directory record Official record
Conditions
Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
Interventions
CBT-OSA, Sleep Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 5, 2026, 11:40 AM EDT