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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:31 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 328 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Continuous positive airway pressure Clear all

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Early NIPPV, Standard NIPPV; Device
Lead sponsor: Edward Kasaraskis; Other
Eligibility: 18 Years to 80 Years
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2012
U.S. locations: 12
States / cities: Denver, Colorado • Miami, Florida • Lexington, Kentucky + 8 more

Conditions: Pulmonary Ventilation, Capnography
Interventions: Linshom Respiratory Monitoring Device; Device
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Obstructive Sleep Apnea
Interventions: Acetazolamide, Placebo, Continuous Positive Airway Pressure; Drug · Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 50 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Obstructive Sleep Apnea
Interventions: Custom CPAP mask; Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Lungs; Developmental Disorder
Interventions: 129Xe; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Up to 6 Months
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Neuromuscular Diseases
Interventions: Oscillation and Lung Expansion (OLE) therapy; Device
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 5 Years to 80 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Obstructive Sleep Apnea, Insomnia
Interventions: CBT-I, CPAP; Behavioral · Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions: Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm; Drug · Device
Lead sponsor: Clayton Sleep Insititute; Industry
Eligibility: 16 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Sleep Apnea, Obstructive
Interventions: Heated breathing tube (CPAP with ThermoSmart), Non heated breathing tube (CPAP with conventional humidification); Device
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 2
States / cities: Tulsa, Oklahoma

Conditions: Infant Respiratory Distress Syndrome, Respiratory Insufficiency, Apnea of Prematurity
Interventions: Nasal high frequency ventilation; Other
Lead sponsor: Tarah T Colaizy; Other
Eligibility: 7 Days to 3 Months
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Acute Ischemic Stroke, Sleep Apnea
Interventions: continuous positive airway pressure; Procedure
Lead sponsor: Yale University; Other
Eligibility: 50 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
Interventions: MET, ED; Behavioral
Lead sponsor: National Jewish Health; Other
Eligibility: 30 Years to 80 Years
Enrollment: 306 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2015
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Apnea, Sleep, Chronic Fatigue Syndrome
Interventions: Nasal CPAP treatment during sleep; Other
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 32 Years to 52 Years · Male only
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Northport, New York

Conditions: Obstructive Sleep Apnea
Interventions: Auto-adjusting CPAP; Device
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Obstructive Sleep Apnea, Pregnancy Related, Insulin Sensitivity
Interventions: Continuous Positive Airway Pressure; Device
Lead sponsor: Barnes-Jewish Hospital; Other
Eligibility: 20 Years to 39 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Obstructive Sleep Apnea
Interventions: Continuous positive airway pressure apparatus; Device
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 90 Years
Enrollment: 296 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania

Conditions: COVID-19, Sleep Apnea
Interventions: Continuous positive airway pressure; Device
Lead sponsor: Venkatesh Krishnamurthy; Other
Eligibility: 18 Years to 75 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Atrial Fibrillation
Interventions: Liraglutide, RFM, Anti Arrhythmics, Afib Catheter Ablation; Drug · Other · Procedure
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions: Continuous Positive Airway Pressure; Device
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Fontana, California

Conditions: Sleep Apnea, Obstructive, Anovulation, Polycystic Ovarian Syndrome
Interventions: CPAP; Device
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years to 35 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Interventions: CPAP, CBT, sham CPAP, CC; Device · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obstructive Sleep Apnea
Interventions: Active CPAP, Sham CPAP; Device
Lead sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center; Other
Eligibility: 30 Years to 70 Years · Male only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Torrance, California

Conditions: Obstructive Sleep Apnea, Diabetes Mellitus
Interventions: PreDx Diabetes Risk Score; Behavioral
Lead sponsor: Mike O'Callaghan Military Hospital; Federal
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Headache Disorder, Sleep Disorder, Obstructive Sleep Apnea
Interventions: Continuous positive airway pressure (CPAP); Device
Lead sponsor: Walter Reed Army Medical Center; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

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Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

Non-invasive Tidal Volume Monitoring Using the Linshom Respiratory Monitoring Device

Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health

3D Printer Modified CPAP Mask for Obstructive Sleep Apnea

Use of Hyperpolarized 129Xe MR Lung Imaging in Infants

Oscillation and Lung Expansion (OLE) Therapy for Treatment of Neuromuscular Disease (NMD) Patients

Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep Apnea

Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure

Titration Pressures in Sleep Apnea Patients Using ThermoSmart® Versus Conventional Humidification

Nasal High Frequency Ventilation in Preterm Infants: A Pilot Study

Continuous Positive Airway Pressure for the Treatment of Stroke

Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)

Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment

Initiation of Auto-adjusting CPAP for Newly Diagnosed OSA in Hospitalized Patients

Obstructive Sleep Apnea Treatment and Insulin Sensitivity in Pregnancy

Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea

CPAP Efficacy in Post-COVID-19 Patients With Sleep Apnea

Liraglutide Effect in Atrial Fibrillation

Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients

Using CPAP to Improve Menstruation in Women With Polycystic Ovarian Syndrome and Obstructive Sleep Apnea

Understanding the Sleep Apnea/Insomnia Interaction

Reproductive Aging and Obstructive Sleep Apnea

Assessing the Risk of Developing Type II Diabetes Using Serum Biomarkers in Patients Diagnosed With Obstructive Sleep Apnea

Analysis of the Prevalence and Characteristics of Concomitant Sleep and Headache Disorders, and the Efficacy of CPAP Treatment for Headache Among Those Patients Diagnosed With Obstructive Sleep Apnea