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Showing 1–24 of 170 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Contrast - Enhanced Ultrasound Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Diagnostic Utility of MRI in Female Patients With Nipple Discharge: A Prospective Trial

NCT02818946
View directory record Official record
Conditions
Disorder of Nipple, Breast Neoplasms
Interventions
MRI
Device
Lead sponsor
Duke University
Other
Eligibility
22 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 10, 2026, 4:40 PM EDT
Not listed No phase listed Observational

Evaluation of Cirrhosis and Malignant Hepatic Lesions Using Novel MR Contrast Agents

NCT01341132
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
MRI Scan of the Liver enhanced with Eovist
Procedure
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2011 · Synced Sep 10, 2026, 4:40 PM EDT
Terminated Phase 4 Interventional Results available

Correlation of Renal Mass Pathologic Grade and Contrast Enhanced Ultrasound (CEUS)

NCT03821376
View directory record Official record
Conditions
Renal Malignant Tumor
Interventions
Contrast enhanced ultrasound with Lumason
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Phase 1 Interventional

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

NCT00655655
View directory record Official record
Conditions
Gastrinoma, Glucagonoma, Insulinoma, Metastatic Gastrointestinal Carcinoid Tumor, Metastatic Pheochromocytoma, Pancreatic Polypeptide Tumor, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell Carcinoma, Recurrent Melanoma, Recurrent Neuroendocrine Carcinoma of the Skin, Recurrent Non-small Cell Lung Cancer, Recurrent Pheochromocytoma, Recurrent Renal Cell Cancer, Somatostatinoma, Stage III Neuroendocrine Carcinoma of the Skin, Stage IV Melanoma, Stage IV Non-small Cell Lung Cancer, Stage IV Renal Cell Cancer, Thyroid Gland Medullary Carcinoma, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
everolimus, vatalanib, pharmacological study, laboratory biomarker analysis, dynamic contrast-enhanced magnetic resonance imaging, ultrasound imaging
Drug · Other · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Phase 2 Interventional Results available

The Role of Contrast Enhanced Ultrasound in Appendicitis

NCT03687502
View directory record Official record
Conditions
Acute Appendicitis
Interventions
Sulfur hexafluoride lipid-type A microspheres
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
8 Years to 17 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Early Phase 1 Interventional

Real-Time Contrast-Enhanced Ultrasonography and Shear Wave Elastography in Predicting Treatment Response in Patients With Soft Tissue Sarcoma

NCT02384473
View directory record Official record
Conditions
Adult Soft Tissue Sarcoma, Bone Sarcoma, Retroperitoneal Sarcoma
Interventions
Real-Time CEUS, SWE, Definity Suspension for Injection, Philips Shear Wave Elastography
Procedure · Drug · Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Withdrawn Not applicable Interventional

Contrast-Enhanced Ultrasound in Diagnosing Patients With Liver Cancer Undergoing Yttrium-90 Radioembolization

NCT03300401
View directory record Official record
Conditions
Hepatocellular Carcinoma
Interventions
Perflutren Lipid Microspheres, Sulfur Hexafluoride Lipid Microspheres, Dynamic Contrast-Enhanced Ultrasound Imaging, Positron Emission Tomography, Computed Tomography, Yttrium-90 (90Y)
Drug · Device · Biological
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 15, 2019 · Synced Sep 10, 2026, 4:40 PM EDT
Terminated Phase 2 Interventional Results available

BR55 in Characterization of Ovarian Lesions

NCT03493464
View directory record Official record
Conditions
Ovarian Cancer
Interventions
BR55
Drug
Lead sponsor
Bracco Diagnostics, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Imaging of Lymphatic Anomalies

NCT02744027
View directory record Official record
Conditions
Gorham Disease, Lymphatic Diseases, Lymphangiomatosis
Interventions
Dynamic Contrast Enhanced Magnetic Resonance Lymphangiography (DCMRL), Heavy Weighted T2 Imaging (T2W), Lymph Node Access
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Sep 10, 2026, 4:40 PM EDT
Recruiting Phase 2 Interventional

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

NCT06635980
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Breast Carcinoma, Triple-Negative Breast Carcinoma
Interventions
Biopsy of Breast, Biospecimen Collection, Breast Surgery, Chemotherapy, Computed Tomography, Contrast Enhanced Digital Mammography, Hypofractionated Radiation Therapy, Magnetic Resonance Imaging, Positron Emission Tomography, Survey Administration, Tissue Collection, Ultrasound Imaging
Procedure · Drug · Radiation + 1 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Recruiting Not applicable Interventional

CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules

NCT06184152
View directory record Official record
Conditions
HCC, Hepatocellular Carcinoma
Interventions
CEUS imaging, aMRI imaging
Diagnostic Test
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Recruiting Not applicable Interventional

Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma

NCT05281731
View directory record Official record
Conditions
Glioblastoma, Glioblastoma Multiforme
Interventions
Sonobiopsy, Research blood, Cancer Personalized Profiling, Definity®
Device · Procedure · Genetic
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 10, 2026, 4:40 PM EDT
Not listed Phase 4 Interventional

Risk Assessment of Carotid Plaques Using 3D Contrast-Enhanced Ultrasound

NCT04643431
View directory record Official record
Conditions
Carotid Atherosclerosis
Interventions
Perflutren
Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

CESM ABMR Breast Cancer Screening Trial

NCT03517813
View directory record Official record
Conditions
Breast Cancer Screening
Interventions
Contrast-enhanced Spectral Mammography (CESM)
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Phase 4 Interventional Results available

Academic-Industrial Partnership for Translation of Acoustic Angiography

NCT03544268
View directory record Official record
Conditions
Signs and Symptoms
Interventions
Acoustic Angiography, Definity
Device · Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Phase 2 Interventional Results available

Contrast-Enhanced Ultrasound for the Prediction of Bile Duct Cancer Response to Radioembolization Treatment

NCT05328167
View directory record Official record
Conditions
Intrahepatic Cholangiocarcinoma
Interventions
Perflutren Protein-Type A Microspheres, Contrast-Enhanced Ultrasound
Drug · Procedure
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Early Phase 1 Interventional

Pazopanib/DCE-MRIs in Renal Cell Carcinoma (RCC)

NCT01221506
View directory record Official record
Conditions
Carcinoma, Renal Cell
Interventions
Pazopanib, DCE-MRI and Quantitative Doppler Ultrasound
Drug · Device
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Sep 10, 2026, 4:40 PM EDT
Completed No phase listed Observational

Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery

NCT00033397
View directory record Official record
Conditions
Breast Cancer
Interventions
biopsy, magnetic resonance imaging, radiomammography, ultrasound imaging, gadopentetate dimeglumine, chemotherapy
Procedure · Radiation · Drug
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older · Female only
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
5
States / cities
San Francisco, California • Chicago, Illinois • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Early Phase 1 Interventional Results available

Contrast-Enhanced Subharmonic Ultrasound Imaging in Improving Characterization of Adnexal Masses in Patients Undergoing Surgery

NCT03297112
View directory record Official record
Conditions
Adnexal Mass
Interventions
Perflutren Lipid Microspheres, Contrast-Enhanced Subharmonic Ultrasound Imaging
Drug · Procedure
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
21 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Prospective, Multi-site Clinical Study to Collect User Feedback Using Affirm® Contrast Biopsy

NCT04671329
View directory record Official record
Conditions
Breast Cancer
Interventions
Affirm Contrast Biopsy procedure
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
40 Years and older · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Phoenix, Arizona • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Use of Contrast Enhanced Spectral Mammography (CESM) for Women With Palpable Breast Abnormalities

NCT02406274
View directory record Official record
Conditions
Breast Abnormalities
Interventions
Contrast Enhanced Spectral Mammography (CESM)
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
25 Years and older · Female only
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Sep 10, 2026, 4:40 PM EDT
Withdrawn Not applicable Interventional

Contrast Enhanced Endoscopic Ultrasound for Vascular Involvement in Pancreatic Lesions

NCT01526590
View directory record Official record
Conditions
Pancreatic Tumors
Interventions
Definity Contrast
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Sep 10, 2026, 4:40 PM EDT
Active, not recruiting Not applicable Interventional

Stellate Ganglion Block for PTSD

NCT05169190
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Stellate Ganglion Block, Sham Stellate Ganglion Block
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
6
States / cities
Long Beach, California • Tampa, Florida • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 10, 2026, 4:40 PM EDT
Completed Early Phase 1 Interventional

Open-label Pilot Evaluating Renal Lesions w/ Contrast-enhaced US in Patients w/ Renal Cancer

NCT01751529
View directory record Official record
Conditions
Kidney Cancer
Interventions
Contrast-enhanced Ultrasound, Perflutren lipid
Procedure · Drug
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Sep 10, 2026, 4:40 PM EDT