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Showing 1–24 of 31 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Control Daily Disposable Soft Contact Lenses Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process

NCT06967129
View directory record Official record
Conditions
Astigmatism
Interventions
Investigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology (4GT) lines with extended mini-stack hydration using propylene glycol (PG) as the hydration solvent., ACUVUE® Oasys 1-Day for Astigmatism (AO1DfA) soft contact lenses manufactured on 3rd Generation Technology (3GT) legacy lines using isopropyl alcohol (IPA) as the hydration solvent.
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
281 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
20
States / cities
Mission Viejo, California • San Diego, California • Jacksonville, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population

NCT04310566
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens (senofilcon A c3), Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Jacksonville, Florida • Maitland, Florida • Pittsburg, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Evaluation of Daily Disposable Toric Soft Contact Lenses Manufactured With an Alternative Hydration Process

NCT05427539
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Jacksonville, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2023 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Evaluating Two Multifocal Daily Disposable Contact Lenses

NCT05579886
View directory record Official record
Conditions
Presbyopia
Interventions
Control Lens, Test Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
42 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Ocoee, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Connecting Contact Lenses and Digital Technology

NCT02921087
View directory record Official record
Conditions
Asthenopia, Contact Lenses, Ocular Accommodation, Convergence, Excess
Interventions
Test Daily Disposable Soft Contact Lenses, Control Daily Disposable Soft Contact Lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

A 6-Hour Clinical Evaluation of New Daily-Wear Soft Contact Lenses

NCT03235089
View directory record Official record
Conditions
Myopia
Interventions
Test Lens, Control Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Approved Contact Lenses

NCT07174596
View directory record Official record
Conditions
Visual Acuity
Interventions
B+L Infuse spherical soft contact lenses, J&J ACUVUE OASYS 1-Day spherical soft contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
4
States / cities
Roswell, Georgia • New Bremen, Ohio • Salem, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Evaluation of Two Daily Disposable Toric Lens Designs in Habitual Soft Contact Lens Wearers

NCT04831515
View directory record Official record
Conditions
Astigmatism
Interventions
Lens A, Lens B
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
4
States / cities
Whittier, California • Sarasota, Florida • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 19, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Wavelength Intervention for Nearsighted Kids

NCT06598423
View directory record Official record
Conditions
Myopia
Interventions
Specialized soft contact lens 1, Specialized soft contact lens 2
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
7 Years to 12 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of a Daily Disposable Multifocal Contact Lens to a Marketed Product

NCT05101252
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A C3, Dailies Total 1 Multifocal Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Roswell, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT06749496
View directory record Official record
Conditions
Astigmatism
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 19, 2026, 4:54 AM EDT
Completed No phase listed Interventional Results available

Clinical Validation of the Apollo Daily Disposable Soft Contact Lenses

NCT05035017
View directory record Official record
Conditions
Myopia
Interventions
Test Lens, Control Lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin

NCT02347631
View directory record Official record
Conditions
Soft Contact Lenses, Myopia
Interventions
Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 38 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens

NCT05927753
View directory record Official record
Conditions
Refractive Error - Myopia Bilateral
Interventions
Deseyne Daily Disposable Contact Lens (Test Device)
Device
Lead sponsor
Bruno Vision Care
Industry
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Sep 19, 2026, 4:54 AM EDT
Recruiting Not applicable Interventional

Performance of Two Daily Disposable Multifocal Contact Lenses

NCT07444658
View directory record Official record
Conditions
Presbyopia
Interventions
Lens A (kalfilcon A), Lens B (stenfilcon A)
Device
Lead sponsor
CooperVision International Limited (CVIL)
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population; Part 2

NCT04615507
View directory record Official record
Conditions
Visual Acuity
Interventions
JJVC Investigational Multifocal Contact Lens, Dailies Total 1® Multifocal Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
6
States / cities
Jacksonville, Florida • Roswell, Georgia • Raytown, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Two Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05291936
View directory record Official record
Conditions
Ocular Physiology
Interventions
PRECISION1® for Astigmatism Contact Lenses, MyDay® Toric Soft Contact Lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
5
States / cities
Jacksonville, Florida • Longwood, Florida • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Hyperopic Population

NCT04567186
View directory record Official record
Conditions
Visual Acuity
Interventions
Investigational senofilcon A C3 Multifocal Lens, delefilcon A Multifocal Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
7
States / cities
Bakersfield, California • Mission Viejo, California • Jacksonville, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)

NCT01829191
View directory record Official record
Conditions
Myopia
Interventions
Soft Contact Test Lens A, Soft Contact Test Lens C
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
8 Years to 12 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Delefilcon A and Verofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT05502289
View directory record Official record
Conditions
Ocular Physiology
Interventions
TEST LENS, CONTROL LENS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Vestal, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses

NCT04529109
View directory record Official record
Conditions
Visual Acuity
Interventions
etafilcon A investigational cosmetic lens 1, etafilcon A investigational cosmetic lens 2
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 29 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Jacksonville, Florida • Tyler, Texas
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses

NCT04968925
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Precision 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
10
States / cities
Mission Viejo, California • Maitland, Florida • Orange Park, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

1 Week Crossover Study Between Two Soft Contact Lenses

NCT06611410
View directory record Official record
Conditions
Myopia
Interventions
Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 19, 2026, 4:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear

NCT06161012
View directory record Official record
Conditions
Ocular Physiology
Interventions
Senofilcon A contact lenses (TEST), Delefilcon A contact lenses (CONTROL)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Longwood, Florida • Maitland, Florida • Granville, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 19, 2026, 4:54 AM EDT