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Showing 1441–1464 of 17,751 matching trials from the live ClinicalTrials.gov search.
Enrolling by invitation Not applicable Interventional

Effect of PEEP on Cardiac Function

NCT07531602
Conditions
Cardiac Surgery Subjects
Interventions
EIT Guided PEEP Trial
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Generalized Tonic Clonic Seizures
Interventions
Pregabalin Dose Level 1, Pregabalin Dose Level 2, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
5 Years to 65 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
12
States / cities
Loxahatchee Groves, Florida • Orlando, Florida • Port Charlotte, Florida + 6 more
Conditions
Transient Tachypnea of the Newborn, TTN, Respiratory Distress Syndrome, RDS
Interventions
Respiratory Distress Group, Control Group
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
28 Weeks and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of the Family Room App on Caregivers

NCT06463158
Conditions
Well-Being, Psychological, Engagement, Satisfaction, Consumer
Interventions
Family Room Application
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Omaha, Nebraska
Conditions
Postherpetic Neuralgia
Interventions
ATx08-001, Placebo
Drug
Lead sponsor
Aestus Therapeutics
Industry
Eligibility
18 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
9
States / cities
Chandler, Arizona • Peoria, Arizona • Cutler Bay (Miami), Florida + 5 more
Conditions
Depression, Depressive Disorder, Depressive Symptoms, Depressive Disorder, Major, Depressive Episode, Depression Severe
Interventions
TNX-601 ER, Placebo
Drug
Lead sponsor
Tonix Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
27
States / cities
Little Rock, Arkansas • Bellflower, California • Glendale, California + 24 more
Conditions
Hypertension
Interventions
Remote patient monitoring for hypertension
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
65 Years to 85 Years
Enrollment
7,068 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Patent Ductus Arteriosus After Premature Birth
Interventions
Ibuprofen
Drug
Lead sponsor
IWK Health Centre
Other
Eligibility
Up to 72 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Orange, California • San Diego, California • Oklahoma City, Oklahoma
Conditions
Caregivers, Emotions, Emotion Regulation, Stress, Psychological, Psychophysiology
Interventions
Cognitive Emotion Regulation Training via Psychological Distancing, Cognitive Emotion Regulation Training via Reinterpretation
Behavioral
Lead sponsor
Bryan Denny
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Completed Phase 3 Interventional Accepts healthy volunteers

Exercise and Physical Fitness for Persons With Knee Osteoarthritis

NCT00265447
Conditions
Knee Osteoarthritis
Interventions
Strength training, Aerobic conditioning, Delayed exercise
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
50 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Suicide, Distress, Emotional
Interventions
Treatment as usual, Barrier Reduction Intervention
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Menopause, Postmenopausal Vaginal Atrophy
Interventions
estradiol, 10 mcg
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
45 Years and older · Female only
Enrollment
309 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
51
States / cities
Mobile, Alabama • Montgomery, Alabama • Phoenix, Arizona + 45 more
Completed Not applicable Interventional

Promoting Cholesterol Screening

NCT01930149
Conditions
Cardiovascular Diseases, Lipid Testing, Primary Prevention of Cardiovascular Disease
Interventions
Mailed patient outreach intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 75 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Flagstaff, Arizona • Chicago, Illinois
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
Dexamethasone postoperative, Standard of Care
Drug
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Childhood Obesity, Pediatric Obesity, Quality of Life, Cardiovascular Risk Factor
Interventions
Hearts & Parks
Behavioral
Lead sponsor
Duke University
Other
Eligibility
5 Years to 18 Years
Enrollment
327 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
3
States / cities
Durham, North Carolina
Conditions
Diabetic Foot Ulcer, Diabetes Mellitus, Type 2
Interventions
EnhanceFitness community exercise program
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Not listed Phase 4 Interventional Accepts healthy volunteers

Addition of Clonidine to Ropivacaine in Adductor Canal Block

NCT03057015
Conditions
Postoperative Pain
Interventions
Clonidine, Placebo, Ropivacaine, Dexamethasone, Epinephrine
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Completed Not applicable Interventional Results available

Eating Disorder Prevention Program for Women With T1D

NCT05264376
Conditions
Eating Disorders, Type 1 Diabetes
Interventions
Diabetes Body Project, Educational Control
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 30 Years · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Stanford, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Almonds, Gut Microbiome and Kids

NCT07636850
Conditions
Dysbiosis, Cardiometabolic Health Indicators
Interventions
Creamy Richards 100% Almonds! Creamy Natural Almond Butter, Cadbury Milk Chocolate Spread
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Infertility, Recurrent Pregnancy Loss
Interventions
PGD, PGD
Genetic · Procedure
Lead sponsor
Reprogenetics
Industry
Eligibility
32 Years to 42 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
4
States / cities
Beverly Hills, California • Highland Park, Illinois • Livingston, New Jersey + 1 more
Conditions
Upper Extremity Dysfunction, Lower Extremity Problem
Interventions
Decision aid
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
6
States / cities
Austin, Texas
Completed Phase 3 Interventional Results available

Add-on to Thiazolidinedione (TZD) Failures

NCT00683878
Conditions
Type 2 Diabetes
Interventions
Dapagliflozin, Placebo matching Dapagliflozin, Thiazolidinedione (Pioglitazone)
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years and older
Enrollment
972 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
57
States / cities
Anniston, Alabama • Ozark, Alabama • Phoenix, Arizona + 51 more
Conditions
Lung Carcinoma
Interventions
Best Practice, Health Promotion and Education, Questionnaire Administration
Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
4
States / cities
Hillsboro, Oregon • Portland, Oregon
Conditions
Influenza, Vaccine
Interventions
cH8/1N1 LAIV, AS03-adjuvanted cH5/1N1 IIV, cH5/1N1 IIV, AS03-adjuvanted cH8/1N1 IIV, Normal saline, Phosphate buffered saline (PBS)
Biological
Lead sponsor
PATH
Other
Eligibility
18 Years to 39 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Durham, North Carolina • Cincinnati, Ohio