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Conditions: Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits, Breast Feeding, Physical Activity, Childhood Obesity, Feeding Behavior
Interventions: Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC); Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 14 Years to 24 Years · Female only
Enrollment: 259 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2023
U.S. locations: 3
States / cities: Fort Defiance, Arizona • Whiteriver, Arizona • Shiprock, New Mexico

Conditions: Violence
Interventions: Fourth R; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 11 Years to 15 Years
Enrollment: 3,028 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 2
States / cities: Houston, Texas • Sugar Land, Texas

Conditions: Colorectal Cancer
Interventions: Risk Assessment; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 50 Years to 75 Years
Enrollment: 352 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hypertension
Interventions: Heart Health and Nutrition for Life (HHNL), Self-Measured Blood Pressure; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years to 84 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Adolescent Behavior, Emergency Department, Abuse Physical, Abuse Mental, Abuse Verbal, Abuse Domestic, HEART, Intimate Partner Violence
Interventions: ED-HEART; Behavioral
Lead sponsor: Children's Mercy Hospital Kansas City; Other
Eligibility: 14 Years to 19 Years
Enrollment: 175 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Kansas City, Missouri

Conditions: Obesity, Obesity, Childhood, Obesity; Familial
Interventions: Home visitation + HABITS program, Standard home visitation program; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 0 Years to 75 Years
Enrollment: 296 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Low Back Pain, Neck Pain
Interventions: Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT), Delivery of Patient Education Materials (System Intervention - Usual Care), Delivery of Patient Education Materials (System Intervention - STEPPT), Referral Specialist Training (System Intervention - Usual Care), Patient Health Navigator Training (System Intervention - STEPPT), Care Navigation (System Intervention - STEPPT), Care navigation audit and feedback (System Intervention - STEPPT), Primary Care Provider training (Provider Intervention - STEPPT), Nurse/Medical Assistant Training (Provider Intervention - STEPPT), Provider feedback on PT referral and adherence (Provider Intervention - STEPPT), Patient education on spine pain condition (Patient Intervention - Usual Care), Patient education on spine pain condition (Patient Intervention - STEPPT), Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care), Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT), Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT), Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care), Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT), Care Navigation (System Intervention - Usual Care), Monitoring of PT referral and adherence rates (System Intervention - STEPPT), Monitoring of PT referral and adherence rates (System intervention - Usual Care); Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older
Enrollment: 17,587 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Diego, California

Conditions: Gynecologic Neoplasm, Brachytherapy, Therapeutic Touch, Endometrial Cancer, Cervical Cancer, Vaginal Cancer, Vulvar Cancer
Interventions: Reiki therapy; Other
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older · Female only
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Skin Neoplasms
Interventions: Indoor tanning intervention, Standard of care control; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 20 Years to 30 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Type 2 Diabetes
Interventions: UMS Strategy, SMS Texting Reminders; Other
Lead sponsor: Northwestern University; Other
Eligibility: 30 Years and older
Enrollment: 452 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Diabetes
Interventions: Promotora-led Intervention, Metformin Therapy, Usual Care; Behavioral · Drug · Other
Lead sponsor: Temple University; Other
Eligibility: 20 Years to 75 Years · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression, Drug Use
Interventions: Families with Pride ("Familias con Orgullo"); Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 13 Years to 19 Years
Enrollment: 306 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: No Evidence of Disease, BRCA1 Syndrome, BRCA2 Syndrome, Hereditary Female Breast Carcinoma, Hereditary Ovarian Carcinoma
Interventions: questionnaire administration, survey administration, counseling intervention, educational intervention; Other
Lead sponsor: City of Hope Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 493 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2026
U.S. locations: 3
States / cities: Duarte, California • Los Angeles, California • Sylmar, California

Conditions: Post-Traumatic Stress Disorder
Interventions: Healing Touch & Guided Imagery; Other
Lead sponsor: Scripps Center for Integrative Medicine; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Cancer, Health Promotion
Interventions: HealthLinks; Other
Lead sponsor: University of Washington; Other
Eligibility: 21 Years and older
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive, Heart Failure，Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions: EHR-based Clinician Jumpstart; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 2,512 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Posttraumatic Stress Disorder, Burns, Traumatic Injury, Acute Stress Disorder, Trauma and Stressor Related Disorders, Trauma and Stress Related Disorders, Stress Disorder, Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Stress Disorders, Traumatic, Acute, Relationship, Social
Interventions: Promotion of Emotional Disclosure for Burns (PoED-B), minimally Enhanced Usual Care control (mEUC); Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Weight Gain Trajectory, BMI, Responsive Parenting, Diet Quality, Implementation
Interventions: Data integration around responsive parenting, Standard Care (in control arm); Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 380 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: University Park, Pennsylvania

Conditions: HIV Infections, Substance Use
Interventions: Safer Sex Skills Building (SSB); Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 380 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Richmond, Virginia

Conditions: Type 1 Diabetes, Family Relations
Interventions: The 3Ms 2.0 Intervention, Educational Attention Control (EAC); Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 10 Years to 14 Years
Enrollment: 216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 4
States / cities: Washington D.C., District of Columbia • Detroit, Michigan • Memphis, Tennessee

Conditions: BRCA1 Mutation, POLD1 Gene Mutation, CDKN2A Mutation, BRCA2 Mutation, POLE Gene Mutation, APC Gene Mutation, ATM Gene Mutation, MLH1 Gene Mutation, BARD1 Gene Mutation, MSH2 Gene Mutation, BRIP1 Gene Mutation, MSH6 Gene Mutation, CHEK2 Gene Mutation, PMS2 Gene Mutation, PALB2 Gene Mutation, EPCAM Gene Mutation, RAD51C Gene Mutation, BMPR1A Gene Mutation, RAD51D Gene Mutation, SMAD4, PTEN Gene Mutation, GREM1
Interventions: Intervention Arm At-risk Relative/ARR Contacts, MyGene Portal, Standard of Care; Behavioral
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 25 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 8
States / cities: Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more

Conditions: Cancer
Interventions: Capacity Enhancement, Standard Dissemination; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 21 Years and older
Enrollment: 348 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 3
States / cities: Boston, Massachusetts • Medford, Massachusetts

Conditions: Lifestyle
Interventions: Yoga, Cognitive Behavioral Therapy, Music; Behavioral
Lead sponsor: Imad Najm MD; Other
Eligibility: 18 Years to 75 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Blood Pressure
Interventions: Multidimensional Sleep Health Promotion Intervention; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 30 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: New York, New York

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Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months

School Based Program to Prevent Teen Dating Violence

Risk Stratification to Promote Effective Shared Decision-Making for Colorectal Cancer Screening

WEAVE NM: Heart Health and Nutrition for Life

Emergency Department Healthcare Education Assessment and Response for Teen Relationships: A Pilot Feasibility Study

Healthy Homes, Healthy Habits

Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)

Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies

Skin Health in Young Adults - Preventing Indoor Tanning and Promoting Sun Protection

Promoting the Universal Medication Schedule Via Mobile and EHR Technologies

Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

Families With Pride ("Familias Con Orgullo").

Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer

Healing Touch & Guided Imagery for Posttraumatic Stress Disorder Symptoms

Increasing Implementation of Evidence-based Interventions at Low-wage Worksites

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

Early Intervention to Prevent Development of PTSD in Burn Survivors and Their Caregivers

Evaluating Care Integration Between Pediatric Primary Care Providers and WIC Nutritionists

Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women

Family Intervention for Black Teens With Type 1 Diabetes

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Promoting Organizational Capacity to Implement Cancer Control Programs Among Latino Churches

Creating a Healthy L.I.F.E: Lifestyle Interventions For Epilepsy

The DREAM Study: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health